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Chemical properties Uses The standard of allowable maximum amount and residue Production methods
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

3-Methylindole Properties

Melting point:
92-97 °C(lit.)
Boiling point:
265-266 °C(lit.)
1.0111 (estimate)
refractive index 
1.6070 (estimate)
3019 | SKATOLE
Flash point:
132 °C
storage temp. 
Store below +30°C.
Crystalline Powder or Flakes
Almost white to pale brown
Water Solubility 
Soluble in water, Ether, Alcohols, Benzene, Acetone, Chloroform.
Light Sensitive
Stable, but light-sensistive. Stench! Incompatible with strong oxidizing agents, strong acids, acid ahydrides, acid chlorides. Combustible.
CAS DataBase Reference
83-34-1(CAS DataBase Reference)
NIST Chemistry Reference
1H-Indole, 3-methyl-(83-34-1)
EPA Substance Registry System
1H-Indole, 3-methyl-(83-34-1)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,N
Risk Statements  36/37/38-51/53
Safety Statements  26-36-61
RIDADR  UN3077 - class 9 - PG 3 - DOT/IATA UN3335 - Environmentally hazardous substances, solid, n.o.s., HI: all (not BR)
WGK Germany  2
RTECS  NM0350000
HS Code  29339920
Hazardous Substances Data 83-34-1(Hazardous Substances Data)
Toxicity MLD in frogs (mg/kg): 1000 s.c. (Bin-Ichi)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

3-Methylindole price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M51458 3-Methylindole 98% 83-34-1 5g $23.1 2018-11-13 Buy
Sigma-Aldrich 90961 3-Methylindole analytical standard 83-34-1 100mg $50.5 2018-11-13 Buy
TCI Chemical M0347 3-Methylindole >98.0%(GC) 83-34-1 1g $14 2018-11-22 Buy
TCI Chemical M0347 3-Methylindole >98.0%(GC) 83-34-1 5g $33 2018-11-22 Buy
Alfa Aesar L03890 3-Methylindole, 99% 83-34-1 5g $21.4 2018-11-13 Buy

3-Methylindole Chemical Properties,Uses,Production

Chemical properties

It is a kind of white crystal. The boiling point is 265-266 ° C; melting point is 93-96 ° C; soluble in 95% ethanol and oil spices three times of its volume. It has the indole-like incense of animals with a salty and strong flavor. The flavor is very strong, with a solid proliferating ability and a long lasting long time. High concentration of it makes people disgusting; only a very low concentration bears a large civet-like and animals-like incense. Moreover, It has a warm ripe fruit-like taste.


1. 3-Methylindole has perfect fragrant value, often used as a fixative, but only used for the trace analysis of floral fragrance in comparison to large civet. It is also used to prepare large civet incense. A combination use with phenylacetic acid, cynomolone or giant ring ketone can get a fine natural animal fragrance. The ultimate trace analysis is used for grape, cheese, fruit, nuts and other fragrant flavor.
2. 3-methylindole has an unpleasant odor, while there is a pleasant fragrance after an enough dilution, especially the smell of civet-based incense. It will be effective in the cheese, nuts, grapes and other products by adding only a small amount. It can acquire a fish flavor when adding to seafood essence.
3. Used for organic synthesis reagents.
4. Used as a biochemical reagent with an inhibiting effect on trypsin. There is a floral fragrance after macrodilution. It is used in cigarettes, perfume in the fragrance, fragrance agent and food spices.
5. pharmaceutical intermediates; perfume fixative.

The standard of allowable maximum amount and residue

Name of additives: β-methyl indole
Name of food allowable for the additive: food
Function of the additive:Spices used in food
Maximum allowable amount (g/kg):The amount of spices to compound essence should be lower than the allowable maximum amount and residue listed in GB 2760.
Maximum allowable residue (g/kg):

Production methods

3-Methylindole present in civet, human, cheese, milk and tea. Propionaldehyde and phenylhydrazine can be heated to remove water molecules to obtain propanal phenylhydrazone in industrial production, and then the intermediates heated with zinc chloride or sulfuric acid, through the removal of ammonia molecules can obtain 3-Methylindole.

Chemical Properties

slightly brown platelets


insect attractant


A naturally abundant pneumotoxin, found primarily in mammalian feces providing its strong fecal odor. In lower concentrations however, the compound has a pleasent aroma, giving orange blossoms and ja smine their pleasing scent. It is often a component of commercial fragrances and perfumes.


A highly fluorescent guanosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3?5?phosphodiester linkage using an automated DNA synthesizer


ChEBI: A methylindole carrying a methyl substituent at position 3. It is produced during the anoxic metabolism of L-tryptophan in the mammalian digestive tract.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.

Metabolic pathway

Three major metabolites of 14C-skatole are found in the plasma/urine of pigs given skatole and are identified as 6-sulfatoxyskatole, 3-hydroxy-3- methyloxindole, and the mercapturate adduct of skatole, 3-[(N-acetylcysteine-S-yl)methyl]indole. For other pathways, see the references in the text.

Purification Methods

Crystallise skatole from *benzene or pet ether (m 96.5o). It has also been purified by zone melting. The picrate has m 182o (from Et2O or Et2O/MeOH). [Beilstein 20 III/IV 3206, 20/7 V 69.]

3-Methylindole Preparation Products And Raw materials

Raw materials

Preparation Products

3-Methylindole Suppliers

Global( 313)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3217 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Hubei Jusheng Technology Co.,Ltd.
86-155-27864001 CHINA 18004 58
0086-13720134139 CHINA 955 58
career henan chemical co
+86-371-86658258 CHINA 19990 58
Wuhan Fortuna Chemical Co., Ltd +86-27-59207852 85767163
+86-27-59524646 China 3089 58
Ningbo Taikang Chemical Co., Ltd. +86 (574) 8736-5517
+86 (574) 87367735 China 300 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 400 025 5188
86-025-86918232 China 6449 55
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40395 62

View Lastest Price from 3-Methylindole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-17 3-Methylindole
US $1.00 / kg 1 g 99% 100KG career henan chemical co

3-Methylindole Spectrum

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