PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming

CAS No.
37288-19-0
Chemical Name:
PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming
Synonyms
PC-PLC;phosphatidylinositol diacylglycerol-lyase;PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming;Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilized powder, >=1,000 units/mg protein (Lowry)
CBNumber:
CB22131094
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00131896
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Properties

storage temp. -20°C
form lyophilized powder

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  SZ6116000

PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P8804 Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus buffered aqueous glycerol solution, ≥1,000?units/mg protein (Lowry) 37288-19-0 5UNITS $487 2024-03-01 Buy
Sigma-Aldrich P8804 Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus bufferedaqueousglycerolsolution,≥1,000?units/mgprotein(Lowry) 37288-19-0 25units $1940 2024-03-01 Buy
Sigma-Aldrich P5542 Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilizedpowder,≥1,000?units/mgprotein(Lowry) 37288-19-0 5units $276 2024-03-01 Buy
Sigma-Aldrich P5542 Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilizedpowder,≥1,000?units/mgprotein(Lowry) 37288-19-0 25units $942 2024-03-01 Buy
American Custom Chemicals Corporation ENZ0000745 PHOSPHOLIPASE C, PHOSPHATIDYLINOSITOL-SPECIFIC 95.00% 37288-19-0 5MG $497.71 2021-12-16 Buy
Product number Packaging Price Buy
P8804 5UNITS $487 Buy
P8804 25units $1940 Buy
P5542 5units $276 Buy
P5542 25units $942 Buy
ENZ0000745 5MG $497.71 Buy

PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Chemical Properties,Uses,Production

Uses

Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus has been used:

  • in the hydrolysis of substrates p-nitrophenylphosphorylcholine (p-NPPC) and p-nitrophenylphosphorylphosphate (p-NPP)
  • to cleave glycosylphosphatidylinositol (GPI) anchor of lynx1 protein and its detachment from plasma membrane
  • to cleave immunolabeled HeLa cells

Uses

Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus has been used to cleave GPI-anchored protein from green fluorescent protein- glycosylphosphatidylinositol (GFP-GPI) from the cell membrane. It has also been used in invasion assay to test the involvement of PLAP in T. cruzi invasion to human epithelial type 2 (HEp-2) cells.

General Description

Phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus cereus is a 298 residual protein. It belongs to the class of ubiquitous enzymes. PI-PLC is characterized with a single globular domain and it folds into eight (βα) barrel sheets, out of which only six βα units are found in barrel, lacking helices between strands IV and V and V and VI.

Biochem/physiol Actions

Used for the release of GPI anchored proteins from the membrane.

PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Preparation Products And Raw materials

Raw materials

Preparation Products

PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Beijing OKA biological technology co., LTD 010-62971590 18548936886 3462612863@qq.com China 6912 58
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969 sales@tomums.cn China 4698 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29803 58
Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836 1986399151@qq.com China 9849 58
PC-PLC PI-PLC, 1-Phosphatidyl-D-myo-inositol inositol phosphohydrolase, cyclic-phosphate forming phosphatidylinositol diacylglycerol-lyase Phospholipase C, Phosphatidylinositol-specific from Bacillus cereus lyophilized powder, >=1,000 units/mg protein (Lowry) 37288-19-0