ChemicalBook >> CAS DataBase List >>4'-Hydroxyphenyl Carvedilol
4'-Hydroxyphenyl Carvedilol
- CAS No.
- 142227-49-4
- Chemical Name:
- 4'-Hydroxyphenyl Carvedilol
- Synonyms
- (R)-BM 14686;(S)-BM 14686;(S)-BM 140686;(R)-BM 140686;4-Hydroxycarvedilol;Carvedilol Impurity 12;(R)-4-Hydroxycarvedilol;(S)-4-Hydroxycarvedilol;4'-HYDROXYPHENYL CARVEDILOL;Carvedilol 4-Hydroxy Metabolite
- CBNumber:
- CB2214210
- Molecular Formula:
- C24H26N2O5
- Molecular Weight:
- 422.47
- MDL Number:
- MFCD04039561
- MOL File:
- 142227-49-4.mol
Last updated:2023-05-18 11:31:03
| Melting point | 163-165°C |
|---|---|
| Boiling point | 702.0±60.0 °C(Predicted) |
| Density | 1.305±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.94±0.20(Predicted) |
| color | White to Light Brown |
| FDA UNII | I02L7A715Z |
4'-Hydroxyphenyl Carvedilol price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00928 | 4′-Hydroxy carvedilol | 142227-49-4 | 1MG | $70.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | SMB00928 | 4′-Hydroxy carvedilol | 142227-49-4 | 5MG | $282 | 2024-03-01 | Buy |
| Cayman Chemical | 27172 | 4''-hydroxyphenyl Carvedilol | 142227-49-4 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 27172 | 4''-hydroxyphenyl Carvedilol | 142227-49-4 | 5mg | $356 | 2024-03-01 | Buy |
| TRC | H949120 | 4’-HydroxyphenylCarvedilol | 142227-49-4 | 2mg | $135 | 2021-12-16 | Buy |
4'-Hydroxyphenyl Carvedilol Chemical Properties,Uses,Production
Description
4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.
Chemical Properties
Off-White Solid
Uses
A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.
Uses
4'-Hydroxyphenyl Carvedilol is an optically active metabolite of Carvedilol which is a multiple-action, neurohormonal antagonist that is used in the treatment of hypertension.
Uses
An optically active metabolite of Carvedilol (C184625), a nonselective ?-adrenergic blocker with α1-blocking activity.
Definition
ChEBI: 4'-Hydroxyphenyl Carvedilol is a member of carbazoles.
4'-Hydroxyphenyl Carvedilol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 50)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
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| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Artis Chemistry (Shanghai) Co. Ltd. | 86-21-60936353 | China | 336 | 58 | |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4505 | 50 |
142227-49-4(4'-Hydroxyphenyl Carvedilol)Related Search:
8-Hydroxy Carvedilol
Carvedilol Bisalkylpyrocatechol IMpurity
4'-HYDROXYPHENYL CARVEDILOL
5'-HYDROXYPHENYL CARVEDILOL
(S)-(-)-5'-HYDROXYPHENYL-CARVEDILOL
1of4
(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL
(S)-(-)-4'-HYDROXYPHENYL-CARVEDILOL
(R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
(R)-4-Hydroxycarvedilol
(R)-BM 140686
(R)-BM 14686
(S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
(S)-4-Hydroxycarvedilol
(S)-BM 140686
(S)-BM 14686
4-[2-[[3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]aMino]ethoxy]-3-Methoxyphenol
Carvedilol 4-Hydroxy Metabolite
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
4'-HYDROXYPHENYL CARVEDILOL
4-Hydroxyphenyl CarvedilolQ: What is
4-Hydroxyphenyl Carvedilol Q: What is the CAS Number of
4-Hydroxyphenyl Carvedilol Q: What is the storage condition of
4-Hydroxyphenyl Carvedilol Q: What are the applications of
4-Hydroxyphenyl Carvedilol
4’-Hydroxyphenyl Carvedilol (10mM in DMSO)
Phenol, 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-
4-Hydroxycarvedilol
Carvedilol Impurity 12
4-(2-((3-((9H-Carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-3-methoxyphenol (Carvedilol Impurity)
142227-49-4
C24H26N2O5
Metabolite
Aromatics
Heterocycles
Chiral Reagents
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals