(2-MERCAPTOETHYL)TRIMETHYLSILANE
- CAS No.
- 18143-30-1
- Chemical Name:
- (2-MERCAPTOETHYL)TRIMETHYLSILANE
- Synonyms
- BEST;ETHYLTHIOTRIMETHYLSILANE 97%;2-(trimethylsilyl)-ethanethio;2-(TRIMETHYLSILYL)ETHANETHIOL;2-TRIMETHYLSILANYL-ETHANETHIOL;(2-MERCAPTOETHYL)TRIMETHYLSILANE;2-(trimethylsilyl)ethane-1-thiol;Ethanethiol, 2-(trimethylsilyl)-;(2-Mercaptoethyl)trimethylsilane, BEST;trimethyl(2-sulfanylethyl)silane - [AC78010]
- CBNumber:
- CB2218814
- Molecular Formula:
- C5H14SSi
- Molecular Weight:
- 134.32
- MDL Number:
- MFCD00077888
- MOL File:
- 18143-30-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(Trimethylsilyl)ethanethiol 95% | 364681 | 1g | $271.7 |
| 2-Trimethylsilanyl-ethanethiol | T898635 | 50mg | $130 |
| (2-MERCAPTOETHYL)TRIMETHYLSILANE 95.00% | ORS0000088 | 0.25G | $326 |
| (2-MERCAPTOETHYL)TRIMETHYLSILANE 95.00% | ORS0000088 | 1G | $716.49 |
| Boiling point | 144-146 °C(lit.) |
|---|---|
| Density | 0.839 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 85 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in MeOH, CH2Cl2, THF, and most organic solvents. |
| pka | 10.80±0.10(Predicted) |
| form | liquid |
| Appearance | Colorless to light yellow Liquid |
| BRN | 1732126 |
| InChI | 1S/C5H14SSi/c1-7(2,3)5-4-6/h6H,4-5H2,1-3H3 |
| InChIKey | BCOLNMGFOWHFNI-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)CCS |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226-H315-H319-H335 |
| Precautionary statements | P210-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 10-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | KJ2621000 |
| F | 13 |
| HazardClass | 3.2 |
| PackingGroup | III |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
| Toxicity | mouse,LD50,intraperitoneal,2500mg/kg (2500mg/kg),Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. Vol. 229, Pg. 1011, 1976. |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
(2-MERCAPTOETHYL)TRIMETHYLSILANE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 364681 | 2-(Trimethylsilyl)ethanethiol 95% | 18143-30-1 | 1g | $271.7 | 2025-07-31 | Buy |
| TRC | T898635 | 2-Trimethylsilanyl-ethanethiol | 18143-30-1 | 50mg | $130 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0000088 | (2-MERCAPTOETHYL)TRIMETHYLSILANE 95.00% | 18143-30-1 | 0.25G | $326 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0000088 | (2-MERCAPTOETHYL)TRIMETHYLSILANE 95.00% | 18143-30-1 | 1G | $716.49 | 2021-12-16 | Buy |
(2-MERCAPTOETHYL)TRIMETHYLSILANE Chemical Properties,Uses,Production
Physical properties
bp 144–146 °C [52–54 °C (25 Torr)]; d 0.850.
Uses
2-(Trimethylsilyl)ethanethiol is a reagent used as a monoprotected sulfide dianion equivalent for the two-step installation of a divalent sulfur atom into organic molecules. It participates in the reactions of Thiol Substitution Reactions, Source of Sulfur Acid Derivatives, etc.
Preparation
The high commercial cost of 2-(trimethylsilyl)ethanethiol necessitates methods for its lab scale synthesis. The radical addition of thiolacetic acid to vinyltrimethylsilane occurs thermally to afford a 9:1 ratio of regioisomers, the 1- and 2-(trimethylsilyl)ethyl thiolesters of acetic acid (eq 1). Photochemical initiation may improve the ratio of regioisomers obtained. Purification of the thiolacetate by careful fractional distillation should be performed prior to conversion to the thiol in order to ensure high purity. The conversion to thiol is best performed with LAH3 or methanolic K2CO3, but ammonolysis may also be suitable. Saponification with KOH in water/ethanol is slightly less efficient. Direct radical addition of liquid H2S to vinyl trimethylsilane has been demonstrated, but the procedure is low-yielding and inconvenient.
(2-MERCAPTOETHYL)TRIMETHYLSILANE Preparation Products And Raw materials
Raw materials
Preparation Products
(2-MERCAPTOETHYL)TRIMETHYLSILANE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49958 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
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| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44801 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42934 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12984 | 57 |
