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Methyl 4-chloropicolinate

Methyl 4-chloropicolinate structure

CAS No.: 24484-93-3

Chemical Name:: Methyl 4-chloropicolinate

Synonyms: 4-CHLORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;METHYL 4-CHLOROPYRIDINE-2-CARBOXYLATE;4-chloropicolinate;EOS-62380;IFLAB-BB F2108-0101;oro-2-pyridinecarboxyL;Methyl 4-chloropicolite;METHYL 4-CHLOROPICOLINATE;4-chloropyridine-2-formate;Methyl 4-Chloro-2-picolinate

CBNumber:: CB2224066

Molecular Formula:: C7H6ClNO2

Molecular Weight:: 171.58

MDL Number:: MFCD04116183

MOL File:: 24484-93-3.mol

MSDS File:: SDS

Last updated:2024-04-01 10:12:56

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Methyl 4-chloropicolinate Properties

Melting point	50-52
Boiling point	105-111 °C(Press: 2-3 Torr)
Density	1.294±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	-0.25±0.10(Predicted)
color	Off-White to Beige
InChI	InChI=1S/C7H6ClNO2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3
InChIKey	VTENWIPSWAMPKI-UHFFFAOYSA-N
SMILES	C1(C(OC)=O)=NC=CC(Cl)=C1
CAS DataBase Reference	24484-93-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

Safety Statements

HazardClass

IRRITANT

HS Code

2933399990

NFPA 704

	1
0		0

Methyl 4-chloropicolinate price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000348	4-Chloro-pyridine-2-carboxylic acid methyl ester Aldrich	24484-93-3	1g	$209	2024-03-01	Buy
TCI Chemical	M1832	Methyl 4-Chloro-2-pyridinecarboxylate >98.0%(GC)(T)	24484-93-3	1g	$20	2024-03-01	Buy
TCI Chemical	M1832	Methyl 4-Chloro-2-pyridinecarboxylate >98.0%(GC)(T)	24484-93-3	5g	$38	2024-03-01	Buy
TRC	M294455	Methyl4-Chloropicolinate	24484-93-3	1g	$60	2021-12-16	Buy
Usbiological	M3396-85	Methyl 4-Chloropicolinate	24484-93-3	1g	$333	2021-12-16	Buy

Product number	Packaging	Price	Buy
ADE000348	1g	$209	Buy
M1832	1g	$20	Buy
M1832	5g	$38	Buy
M294455	1g	$60	Buy
M3396-85	1g	$333	Buy

Methyl 4-chloropicolinate Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

Methyl 4-Chloropicolinate (cas# 24484-93-3) is a compound useful in organic synthesis.

Production Methods

The starting material 2-picolinic acid was treated with SOCl2 to generate 4-chloropicolinoyl chloride, and then esterification with MeOH resulted in the formation of methyl 4-chloropicolinate.

Synthesis Reference(s)

Synthetic Communications, 26, p. 2017, 1996 DOI: 10.1080/00397919608003557

Synthesis

To a suspension of 4-chloropyridine-2-carboxylic acid (4.5 g, 29.0 mmol) in methylene chloride (120 mL) was added oxalyl chloride (3.0 mL, 1.2 eq) under Ar2. The reaction was cooled to 0° C., and 500 uL of DMF was added. A large amount of gas was generated in situ. The reaction was stirred at room temperature for 1.5 h and then concentrated. Dry MeOH (50 mL) was added to the crude acyl chloride residue. The reaction was stirred at room temperature for 0.5 h, then quenched with NaHCO3 (5%) to neutral, extracted with EtOAc, and washed with brine. The combined organics were dried over MgSO4, filtered, and concentrated in vacuo to give 5.0 g of a crude solid, which was triturated with 5% EtOAc/hexane to give Methyl 4-chloropicolinate as a light yellow solid (4.5 g, 90%).

Methyl 4-chloropicolinate synthesis

Synthesis of Methyl 4-chloropicolinate from 2-Picolinic acid and Methanol

Methyl 4-chloropicolinate Preparation Products And Raw materials

Raw materials

4-Chloropyridine-2-carboxylic acid 4-Chloro-pyridine-2-carbonyl chloride 2-PYRIDINECARBOXYLICACID CHLORIDE 2-Picolinic acid Methyl picolinate

Methyl 4,6-dichloropyridine-2-carboxylate Methanol

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Preparation Products

4-CHLORO-PYRIDINE-2-CARBONITRILE 4-METHOXYPICOLINALDEHYDE N-Cyclopropyl 4-chloropicolinaMide 4-Chloro-N-methylpicolinamide

Methyl 4-chloropicolinate Suppliers

Global( 468)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3091	58
Wuhan BJM Pharm Inc	+86-027-5234-1919 +8613545198479	sales03@benjaminpharmchem.com	China	671	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7377	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58

Supplier	Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd	58
Wuhan BJM Pharm Inc	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58

View Lastest Price from Methyl 4-chloropicolinate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	Methyl 4-chloropicolinate 24484-93-3	US $170.00-150.00 / kg	100kg	99.99%	100Tons	Hebei Dangtong Import and export Co LTD
2024-01-02	Methyl 4-chloropicolinate 24484-93-3	US $200.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-09-14	Methyl 4-chloropicolinate 24484-93-3	US $100.00 / bag	1bag	99	5000	Hebei Fengqiang Trading Co., LTD

Methyl 4-chloropicolinate
24484-93-3
US $170.00-150.00 / kg
99.99%
Hebei Dangtong Import and export Co LTD

Methyl 4-chloropicolinate
24484-93-3
US $200.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

Methyl 4-chloropicolinate
24484-93-3
US $100.00 / bag
99
Hebei Fengqiang Trading Co., LTD

Methyl 4-chloropicolinate Spectrum

Methyl 4-chloropicolinate(24484-93-3)¹HNMR

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