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Cefmetazole sodium

Cefmetazole sodium structure

CAS No.: 56796-39-5

Chemical Name:: Cefmetazole sodium

Synonyms: C08104;Metafar;Cefmetazone;Cefmetazole-Na;Sodium cefmetazole;Cefmetazole sodium;CS-1170 sodium salt;Cefotetan Impurity 2;Cefmetazole Sodium Salt >Cefmetazole sodium USP/EP/BP

CBNumber:: CB2231321

Molecular Formula:: C15H18N7NaO5S3

Molecular Weight:: 495.52

MDL Number:: MFCD00214260

MOL File:: 56796-39-5.mol

Last updated:2024-04-12 23:00:59

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Cefmetazole sodium Properties

Melting point	>130°C (dec.)
storage temp.	Inert atmosphere,2-8°C
solubility	H2O: soluble50mg/mL
form	powder
color	White to Off-White
Water Solubility	Soluble in water
Sensitive	Hygroscopic
Merck	14,1926
Stability	Hygroscopic
InChIKey	BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference	56796-39-5(CAS DataBase Reference)
FDA UNII	37Y9VR4W7A
NCI Drug Dictionary	cefmetazole sodium

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H315-H317-H319-H334-H335
Precautionary statements	P280-P302+P352-P305+P351+P338
Hazard Codes	Xn,Xi
Risk Statements	36/37/38-42/43
Safety Statements	26-36
WGK Germany	2
RTECS	XI0372200
HS Code	2941.90.3000
Toxicity	LD50 i.v. in rats: >5000 mg/kg (Masuda)

Cefmetazole sodium price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C6048	Cefmetazole sodium salt	56796-39-5	1g	$128	2024-03-01	Buy
Sigma-Aldrich	C6048	Cefmetazole sodium salt	56796-39-5	250mg	$43	2023-06-20	Buy
TCI Chemical	C3029	Cefmetazole Sodium Salt >97.0%(T)	56796-39-5	250mg	$67	2024-03-01	Buy
TCI Chemical	C3029	Cefmetazole Sodium Salt >97.0%(T)	56796-39-5	1g	$237	2024-03-01	Buy
Alfa Aesar	J66348	Cefmetazole sodium, 921 μg/mg	56796-39-5	1g	$87.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
C6048	1g	$128	Buy
C6048	250mg	$43	Buy
C3029	250mg	$67	Buy
C3029	1g	$237	Buy
J66348	1g	$87.65	Buy

Cefmetazole sodium Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial

Uses

Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.

brand name

Zefazone (Pharmacia & Upjohn）.

Clinical Use

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

Cefmetazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Cefmetazole sodium Suppliers

Global( 224)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	893	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Shanghai Longyu Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58

View Lastest Price from Cefmetazole sodium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-12	Cefmetazole sodium 56796-39-5	US $0.00 / kg	1kg	99%	10000kg	Shaanxi TNJONE Pharmaceutical Co., Ltd
2024-04-09	Cefmetazole sodium 56796-39-5	US $0.00 / Kg	1Kg	99%	10kg	Shaanxi TNJONE Pharmaceutical Co., Ltd
2022-02-25	Cefmetazole Sodium 56796-39-5	US $1.60 / KG	200g	99%	30tons	Hong Kong Tiansheng New Material Trading Co., Ltd

Cefmetazole sodium
56796-39-5
US $0.00 / kg
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Cefmetazole sodium
56796-39-5
US $0.00 / Kg
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Cefmetazole Sodium
56796-39-5
US $1.60 / KG
99%
Hong Kong Tiansheng New Material Trading Co., Ltd

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1of4

Cefmetazone 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)- Cefmetazole-Na CS-1170 sodium salt Metafar Sodium cefmetazole (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt Cefmetazole sodium Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt C08104 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[(cyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)- Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt) sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Cefotetan Impurity 2 Cefmetazole Sodium Salt > Cefmetazole sodium USP/EP/BP Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 56796-39-5 59796-39-5 C15H16N7NaO5S3 C15H17N7O5S3 C15H16N7O5S3Na Sulfur & Selenium Compounds A - KAntibiotics Antibacterial Antibiotics A to Antibiotics A-FAntibiotics Chemical Structure Class Interferes with Cell Wall SynthesisAntibiotics Mechanism of Action Penicillins and Cephalosporins (beta-Lactams) Spectrum of Activity Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals