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15(R)-PROSTAGLANDIN E1

15(R)-PROSTAGLANDIN E1 structure

CAS No.: 19313-28-1

Chemical Name:: 15(R)-PROSTAGLANDIN E1

Synonyms: PGE0;13,14-dihydro PGE1;Prostaglandin E0 >AlprostadilImpurity5;13,14-Dihydroprostaglandinee1;13,14-DIHYDROPROSTAGLANDIN E1;Prostaglandin E1 Impurity 5 (PGE0);90% (20% solution in ethyl acetate);13,14-Dihydro-prostaglandin E1 (PGE0);9-oxo-11α,15S-dihydroxy-prostan-1-oic acid

CBNumber:: CB2233138

Molecular Formula:: C20H36O5

Molecular Weight:: 356.5

MDL Number:: MFCD00135208

MOL File:: 19313-28-1.mol

Last updated:2023-06-08 09:03:09

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15(R)-PROSTAGLANDIN E1 Properties

Boiling point	541.4±35.0 °C(Predicted)
Density	1.075±0.06 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	Ethyl Acetate, Methanol, Tetrahydrofuran
form	Colorless to pale yellow oil
pka	4.77±0.10(Predicted)
Stability	Volatile
FDA UNII	C1R6440YGW

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H319-H336

Precautionary statements

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

NFPA 704

	3
2		0

15(R)-PROSTAGLANDIN E1 price More Price(9)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	13610	13,14-dihydro Prostaglandin E1 ≥98%	19313-28-1	500μg	$47	2024-03-01	Buy
Cayman Chemical	13610	13,14-dihydro Prostaglandin E1 ≥98%	19313-28-1	1mg	$87	2024-03-01	Buy
Cayman Chemical	13610	13,14-dihydro Prostaglandin E1 ≥98%	19313-28-1	5mg	$360	2024-03-01	Buy
Cayman Chemical	13610	13,14-dihydro Prostaglandin E1 ≥98%	19313-28-1	10mg	$629	2024-03-01	Buy
American Custom Chemicals Corporation	BIO0000263	13,14-DIHYDRO-PGE1 95.00%	19313-28-1	5MG	$907.14	2021-12-16	Buy

Product number	Packaging	Price	Buy
13610	500μg	$47	Buy
13610	1mg	$87	Buy
13610	5mg	$360	Buy
13610	10mg	$629	Buy
BIO0000263	5MG	$907.14	Buy

15(R)-PROSTAGLANDIN E1 Chemical Properties,Uses,Production

Description

13,14-dihydro Prostaglandin E₁ (13,14-dihydro PGE₁) is a biologically active metabolite of PGE₁ with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC₅₀ values of 31 and 21 nM, respectively. 13,14-dihydro PGE₁ is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE₁ which has an IC₅₀ value of 40 nM. Also, 13,14-dihydro PGE₁ was shown to activate adenylate cyclase in NCB-20 hybrid cells with a K_act value of 668 nM.

Uses

Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.

Definition

ChEBI: 13,14-Dihydro PGE1 is a prostanoid.

15(R)-PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

15(R)-PROSTAGLANDIN E1 Suppliers

Global( 39)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai Synchem Pharma Co., ltd	021-61984905-1 18016477331	synchempharma@aliyun.com	China	6454	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1991	58
Jinan blalong chemical co. LTD	2710913286@.com	1513643261@qq.com	China	14253	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58

Supplier	Advantage
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
ChemStrong Scientific Co.,Ltd	56
Shanghai Synchem Pharma Co., ltd	55
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	58
Jinan blalong chemical co. LTD	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58

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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID 13,14-DIHYDROPROSTAGLANDIN E1 PGE0 13,14-Dihydroprostaglandinee1 13,14-dihydro PGE1 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid (11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid 13,14-Dihydro-prostaglandin E1 (PGE0) Prostan-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,15S)- 9-oxo-11α,15S-dihydroxy-prostan-1-oic acid Prostaglandin E0 > 90% (20% solution in ethyl acetate) Prostan-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,15S)- Prostaglandin E1 Impurity 5 (PGE0) Prostaglandin E0 >90% (20% solution in ethyl acetate) AlprostadilImpurity5 Alprostadil (Prostaglandin E1) Impurity 5 (PGE0) 19313-28-1