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ACV 1
- CAS No.
- 740980-24-9
- Chemical Name:
- ACV 1
- Synonyms
- ACV 1;GLY-CYS-CYS-SER-ASP-PRO-ARG-CYS-ASN-TYR-ASP-HIS-PRO-GLU-ILE-CYS-NH2
- CBNumber:
- CB22456360
- Molecular Formula:
- C71H103N23O25S4
- Molecular Weight:
- 1806.99
- MDL Number:
- MFCD11112203
- MOL File:
- 740980-24-9.mol
Last updated:2023-05-21 10:59:17
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H310-H300-H330 |
| Precautionary statements | P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501 |
ACV 1 Chemical Properties,Uses,Production
Enzyme inhibitor
This neuronal nicotinic acetylcholine receptor antagonist (FW = 1806.98 g/mol; CAS 740980-24-9), also known as Conotoxin Vc1.1, is produced from mRNA in venom duct of Conus victoriae. ACV 1 selectively targets the α9α10 nAChR subtype (IC50 = 19 nM), with weaker action against α6/α3β2β3 (IC50 = 140 nM), α6/α3β4 (IC50 = 980 nM), α3β4 (IC50 = 4200 nM), and α3β2 (IC50 = 7300 nM) nAChR subtypes. ACV-1 suppresses vascular responses to unmyelinated sensory nerve C-fiber activation in rats, as related to pain transmission. ACV-1 and its posttranslationally modified analogues vc1a, [P6O]Vc1.1, and [E14g]Vc1.1 are equally potent at inhibiting ACh-evoked currents mediated by α9α10 nAChRs.
ACV 1 Preparation Products And Raw materials
Raw materials
Preparation Products
ACV 1 Suppliers
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Creative Peptides | info@creative-peptides.com | United States | 6084 | 56 | |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| Creative Peptides | 56 |
| BOC Sciences | 65 |
| MedBioPharmaceutical Technology Inc | 58 |
| ApexBio Technology | 58 |
740980-24-9(ACV 1)Related Search:
ACV 1
GLY-CYS-CYS-SER-ASP-PRO-ARG-CYS-ASN-TYR-ASP-HIS-PRO-GLU-ILE-CYS-NH2
740980-24-9
C71H103N23O25S4