ChemicalBook >> CAS DataBase List >>6-Methoxynicotinamide
6-Methoxynicotinamide
- CAS No.
- 7150-23-4
- Chemical Name:
- 6-Methoxynicotinamide
- Synonyms
- JBSNF-000088;BUTTPARK 182\12-94;6-Methoxynicotinamide;Benzopyrene Impurity 5;JBSNF-000088 (JBSNF000088;6-methoxy-3-pyridinecarboxamide;6-METHOXYPYRIDINE-3-CARBOXAMIDE;3-PYRIDINECARBOXAMIDE, 6-METHOXY-;Inhibitor,JBSNF 000088,inhibit,6-Methoxynicotinamide,JBSNF-000088
- CBNumber:
- CB22463564
- Molecular Formula:
- C7H8N2O2
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD00229166
- MOL File:
- 7150-23-4.mol
Last updated:2023-12-22 14:15:20
| Melting point | 178-180°C |
|---|---|
| Boiling point | 301.6±22.0 °C(Predicted) |
| Density | 1.213±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.17±0.50(Predicted) |
| color | Off-White to Pale Beige |
| InChI | InChI=1S/C7H8N2O2/c1-11-6-3-2-5(4-9-6)7(8)10/h2-4H,1H3,(H2,8,10) |
| InChIKey | KXDSMFBEVSJYRF-UHFFFAOYSA-N |
| SMILES | C1=NC(OC)=CC=C1C(N)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
6-Methoxynicotinamide price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29920 | JBSNF-000088 | 7150-23-4 | 250mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 29920 | JBSNF-000088 | 7150-23-4 | 500mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 29920 | JBSNF-000088 | 7150-23-4 | 1g | $180 | 2024-03-01 | Buy |
| AK Scientific | V7449 | 6-Methoxynicotinamide | 7150-23-4 | 1g | $161 | 2021-12-16 | Buy |
| AK Scientific | J54609 | 6-Methoxynicotinamide | 7150-23-4 | 5g | $360 | 2021-12-16 | Buy |
6-Methoxynicotinamide Chemical Properties,Uses,Production
Description
JBSNF-000088 is a cell penetrant, potent and selective inhibitor of Nicotinamide N-methyltransferase (NNMT) that reduces 1-methyl-nicotinamide (MNA) and improved glucose control in mice models of metabolic disease. JBSNF-000088 potently inhibits growth of PFA ependymoma cells.
Biological Activity
JBSNF-000088 (6-Methoxynicotinamide) is a nicotinamide (NA) analog, a potent inhibitor of Nicotinamide N-methyltransferase (NNMT), against human NNMT (hNNMT), monkey NNMT (mkNNMT) and mouse NNMT (mNNMT) ) with IC50 values of 1.8 μM, 2.8 μM and 5.0 μM.
in vitro
JBSNF-000088 (6-Methoxynicotinamide) has IC 50 values are 1.6 and 6.3 μM for U2OS or differentiated 3T3L1 cells.
target
| Target | Value |
|
hNNMT (Cell-free assay) |
1.8 μM |
|
mkNNM (Cell-free assay) |
2.8 μM |
|
mNNMT (Cell-free assay) |
5.0 μM |
6-Methoxynicotinamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 65)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5657 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 874 | 58 |
View Lastest Price from 6-Methoxynicotinamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | 6-Methoxynicotinamide
7150-23-4
|
US $0.00-0.00 / kg | 20kg | 99% | 200000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2023-12-22 | JBSNF-000088
7150-23-4
|
US $110.00-90.00 / kilogram | 1kilogram | 99% | 10 tons/per week | Henan Tengmao Chemical Technology Co. LTD | |
 |
2023-12-18 | JBSNF-000088
7150-23-4
|
US $110.00-90.00 / kilogram | 1kilogram | 99% | 10 tons/per week | Henan Tengmao Chemical Technology Co. LTD |
-
- 6-Methoxynicotinamide
7150-23-4
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- JBSNF-000088
7150-23-4
- US $110.00-90.00 / kilogram
- 99%
- Henan Tengmao Chemical Technology Co. LTD
-
- JBSNF-000088
7150-23-4
- US $110.00-90.00 / kilogram
- 99%
- Henan Tengmao Chemical Technology Co. LTD
7150-23-4(6-Methoxynicotinamide)Related Search:
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1of4
6-Methoxynicotinamide
3-PYRIDINECARBOXAMIDE, 6-METHOXY-
6-METHOXYPYRIDINE-3-CARBOXAMIDE
BUTTPARK 182\12-94
JBSNF-000088
JBSNF-000088
(JBSNF000088
6-methoxy-3-pyridinecarboxamide
Inhibitor,JBSNF 000088,inhibit,6-Methoxynicotinamide,JBSNF-000088
Benzopyrene Impurity 5
7150-23-4