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ChemicalBook >> CAS DataBase List >>4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Structure
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide structure
CAS No.
1032229-33-6
Chemical Name:
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
Synonyms
A939572;SCD inhibitor;A939572;A-939572;A 939572;SCD1 Inhibitor (DMSO solution);stearoyl-CoA desaturase (SCD) inhibitor;4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide;4-(2-Chlorophenoxy)-N-(3-(methylcarbamoyl)-phenyl)piperidine-1-carboxamide (A939572)
CBNumber:
CB22473855
Molecular Formula:
C20H22ClN3O3
Molecular Weight:
387.86
MDL Number:
MOL File:
1032229-33-6.mol
Last updated:2023-06-30 15:45:59
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4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Properties

Boiling point 633.5±55.0 °C(Predicted)
Density 1.302±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; ≥17.15 mg/mL in DMSO; ≥2.5 mg/mL in EtOH with ultrasonic
form solid
pka 13.65±0.70(Predicted)

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19123 A-939572 ≥98% 1032229-33-6 5mg $55 2024-03-01 Buy
Cayman Chemical 19123 A-939572 ≥98% 1032229-33-6 10mg $105 2024-03-01 Buy
Cayman Chemical 19123 A-939572 ≥98% 1032229-33-6 50mg $495 2024-03-01 Buy
Tocris 4845 A939572 ≥99%(HPLC) 1032229-33-6 10 $173 2021-12-16 Buy
Tocris 4845 A939572 ≥99%(HPLC) 1032229-33-6 50 $742 2021-12-16 Buy
Product number Packaging Price Buy
19123 5mg $55 Buy
19123 10mg $105 Buy
19123 50mg $495 Buy
4845 10 $173 Buy
4845 50 $742 Buy

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Chemical Properties,Uses,Production

Uses

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide is a stearoyl-CoA desaturase 1 (SCD1) inhibitor.

Biological Activity

A 939572 is a potent stearoyl-CoA desaturase 1 (SCD1) inhibitor (IC50 = 0.4 nM). Selective for SCD1 over a range of kinases and hERG channels. Inhibits proliferation of squamous cell carcinoma FaDu cells in vitro. Also induces cell death of undifferentiated human embryonic stem cells (ESCs). Orally bioavailable.

storage

Store at +4°C

References

[1] xin z, zhao h, serby m d, et al. discovery of piperidine-aryl urea-based stearoyl-coa desaturase 1 inhibitors. bioorganic & medicinal chemistry letters, 2008, 18(15): 4298-4302.
[2] Low glycaemic diets alter lipid metabolism to influence tumour growth Authors: Lien Et al. Nature  2021;599:302.

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Suppliers

Global( 90)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Laing Biotechnology Co.,Ltd
+86-13004516015 +86-18149392822 christina@laingbiotec.com China 778 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Suzhou Victorypharm Co.,Ltd. 		+86-13916956214 sales@victory-pharm.com China 1301 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Supplier Advantage
Suzhou Laing Biotechnology Co.,Ltd
58
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
Suzhou Victorypharm Co.,Ltd. 		58
Nantong HI-FUTURE Biology Co., Ltd. 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide pictures 2023-09-24 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
1032229-33-6
 US $0.00-0.00 / g 1g 98% 10kg Suzhou Laing Biotechnology Co.,Ltd
4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide pictures 2020-01-09 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide
1032229-33-6
 US $2.00 / KG 1g 98%min ask Career Henan Chemical Co

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide Spectrum

4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide(1032229-33-6)1HNMR
SCD inhibitor stearoyl-CoA desaturase (SCD) inhibitor A939572 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-Piperidinecarboxamide A939572;A-939572;A 939572 4-(2-Chlorophenoxy)-N-(3-(methylcarbamoyl)-phenyl)piperidine-1-carboxamide (A939572) SCD1 Inhibitor (DMSO solution) 1032229-33-6