ChemicalBook >> CAS DataBase List >>N-De[2-(Methylsulfonyl)ethyl] Lapatinib

N-De[2-(Methylsulfonyl)ethyl] Lapatinib

CAS No.
697299-82-4
Chemical Name:
N-De[2-(Methylsulfonyl)ethyl] Lapatinib
Synonyms
Lapatinib impurity O;Lapatinib Desmesylethyl Imp;Lapatinib Desmesylethyl Impurity;N-De[2-(methylsulfonyl)ethyl] Lapatinib;[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine;6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine;6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine;6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine;4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-
CBNumber:
CB22557856
Molecular Formula:
C26H20ClFN4O2
Molecular Weight:
474.91
MDL Number:
MFCD30720442
MOL File:
697299-82-4.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Properties

Melting point >141oC (dec.)
Boiling point 626.4±55.0 °C(Predicted)
Density 1.376±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 8.83±0.29(Predicted)
form Solid
color Pale Yellow to Light Beige
FDA UNII 6MG3HT6C36

N-De[2-(Methylsulfonyl)ethyl] Lapatinib price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D231270 N-De[2-(methylsulfonyl)ethyl]Lapatinib 697299-82-4 5mg $215 2021-12-16 Buy
Biosynth Carbosynth ID20812 N-De[2-(methylsulfonyl)ethyl] lapatinib 697299-82-4 2mg $324 2021-12-16 Buy
Biosynth Carbosynth ID20812 N-De[2-(methylsulfonyl)ethyl] lapatinib 697299-82-4 5mg $650 2021-12-16 Buy
Biosynth Carbosynth ID20812 N-De[2-(methylsulfonyl)ethyl] lapatinib 697299-82-4 10mg $1050 2021-12-16 Buy
Product number Packaging Price Buy
D231270 5mg $215 Buy
ID20812 2mg $324 Buy
ID20812 5mg $650 Buy
ID20812 10mg $1050 Buy

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Chemical Properties,Uses,Production

Uses

A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Preparation Products And Raw materials

Raw materials

Preparation Products

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
CR Corporation Lomited
fred.wen@crcorporation.cn CHINA 12069 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai CR Corporation Limited 4006653949 fred.wen@crcorporation.cn China 10108 58
[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine 6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine Lapatinib Desmesylethyl Imp Lapatinib impurity O 4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]- Lapatinib Desmesylethyl Impurity 6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine 6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine N-De[2-(methylsulfonyl)ethyl] Lapatinib 697299-82-4 C26H20ClFN4O2 Aromatics Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Sulfur & Selenium Compounds