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Phoxim

Phoxim
Phoxim structure
CAS No.
14816-18-3
Chemical Name:
Phoxim
Synonyms
Foxim;b77488;PHOXIM;Phoxin;B 77488;bay5621;Valaxon;VOLATON;oms1170;Phoxime
CBNumber:
CB2255860
Molecular Formula:
C12H15N2O3PS
Formula Weight:
298.3
MOL File:
14816-18-3.mol

Phoxim Properties

Melting point:
5.55°C
Boiling point:
bp0.01 102°
Density 
d420 1.176
vapor pressure 
2.1×10-3 Pa (20 °C)
refractive index 
nD20 1.5405
storage temp. 
0-6°C
Water Solubility 
1.5 mg l-1 (20 °C)
form 
liquid
InChIKey
ATROHALUCMTWTB-WYMLVPIESA-N
CAS DataBase Reference
14816-18-3(CAS DataBase Reference)
NIST Chemistry Reference
Phoxim(14816-18-3)
EPA Substance Registry System
Phoxim (14816-18-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H311-H317-H330-H361f-H410
Precautionary statements  P201-P260-P273-P280-P304+P340+P310-P403+P233
Hazard Codes  Xn;N,N,Xn
Risk Statements  22-50/53-62-43
Safety Statements  36-60-61-46-36/37
RIDADR  UN 2810
WGK Germany  3
RTECS  MD4740000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29269090
Toxicity LD50 orally in mice: >2000 mg/kg (Vinopal, Fukuto)

Phoxim price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 36197 Phoxim PESTANAL 14816-18-3 100mg $49.8 2019-12-02 Buy

Phoxim Chemical Properties,Uses,Production

Chemical Properties

yellowish oily liquid, Specific gravity: 1.176 (20°C)

Uses

Insecticide.

Uses

Phoxim is used to control stored product insect pests in silos and barns. It is also used to control household insects such as ants and other public health pests. Agricultural targets include caterpillars and soil insects in maize, vegetables, cotton and potatoes.

Safety Profile

Poison by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of CN-, NO,, PO,, and SO,. See also NITRILES.

Metabolic pathway

The primary metabolic step in the metabolism of phoxim in most biological systems is hydrolysis to the oxime, which may occur either oxidatively or via oxidative desulfuration followed by hydrolysis of the oxon which is much more hydrolytically labile. Stage II metabolism in plants involves the oxime group of the oxaminophenylacetonitrile moiety being reduced to an amine followed by its conjugation with malonic acid. Phoxim is one of a quite large group of insecticidal organophosphates which generates tetraethyl pyrophosphate and its thio analogues under the influence of light. These are compounds which are very active as acetylcholinesterase inhibitors and highly toxic to mammals.

Degradation

Phoxim is relatively slowly hydrolysed in water. The half-lives at pH 4,7 and 9 were 26.7, 7.2 and 3.1 days, respectively (PM). Drager (1977) reported a half-life of 145 min in pH 11.5 50% aqueous propanol at 37 °C. It is gradually decomposed under UV irradiation (PM).
The photodecomposition of [32P]phoximon cotton leaves and glass plates was investigated by Drager (1971) who characterised the more hydrophobic organic-soluble components by TLC, GLC and 1H NMR and MS of the purified products. The cotton plants were irradiated with natural sunlight and mercury-vapour lamps at an average light intensity of 3500-4000 lux. On both glass plates and irradiated cotton leaves, phoxim was degraded relatively quickly to one major hydrophobic component, the concentration of which reached a maximum after about one day. This material was identified as the thiono-thiolo rearranged compound O,O-diethyl a-cyanobenzylideneamino-thiophosphorothioate (2). This transformation is an activation step as 2 is a highly active acetylcholinesterase inhibitor. No metabolite 2 was formed on cotton leaves placed in the dark so it can be considered to be a photochemical product rather than a plant metabolite. Additional minor metabolites were tetraethyl pyrophosphate (3) and O,O,O',O'-tetraethyl thiophosphorothioate (4) which formed to a greater extent on the glass plates rather than the cotton leaves.

Phoxim Preparation Products And Raw materials

Raw materials

Preparation Products


Phoxim Suppliers

Global( 125)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1878 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29995 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58
Henan tianfu chemical co. LTD
0371-55170695
info@hnbon.com CHINA 20538 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58

View Lastest Price from Phoxim manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-20 Phoxim
14816-18-3
US $1.00 / kg 1kg 99% Customized career henan chemical co

Phoxim Spectrum


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