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OSI-420

OSI-420 structure

CAS No.: 183320-51-6

Chemical Name:: OSI-420

Synonyms: CP-473420;OSI420 HCl;7-(2’OSI-420 USP/EP/BP;DesMethyl Erlotinib;OSI-420 hydrochloride;6-O-Desmethyl Erlotinib 2;OSI-420 (DesMethyl Erlotinib);Desmethyl Erlotinib (OSI-420);Desmethyl Erlotinib hydrochloride

CBNumber:: CB22561488

Molecular Formula:: C21H22ClN3O4

Molecular Weight:: 415.87

MDL Number:: MFCD22420811

MOL File:: 183320-51-6.mol

MSDS File:: SDS

Last updated:2023-09-04 16:42:00

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OSI-420 Properties

storage temp.	Store at -20°C
solubility	DMSO : 50 mg/mL (120.23 mM; Need ultrasonic)
form	Powder

OSI-420 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	O701030	OSI420	183320-51-6	10mg	$435	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001381	DESMETHYL ERLOTINIB 95.00%	183320-51-6	5MG	$499.47	2021-12-16	Buy
ChemScene	CS-0467	DesmethylErlotinib(hydrochloride) 98.69%	183320-51-6	50mg	$642	2021-12-16	Buy
ChemScene	CS-0467	DesmethylErlotinib(hydrochloride) 98.69%	183320-51-6	5mg	$144	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0001381	DESMETHYL ERLOTINIB 95.00%	183320-51-6	2MG	$234	2021-12-16	Buy

Product number	Packaging	Price	Buy
O701030	10mg	$435	Buy
KIN0001381	5MG	$499.47	Buy
CS-0467	50mg	$642	Buy
CS-0467	5mg	$144	Buy
KIN0001381	2MG	$234	Buy

OSI-420 Chemical Properties,Uses,Production

Uses

OSI 420 can be used in biological study of effects of cytochrome P 450 3A on pharmacokinetic interaction between erlotinib and docetaxel in rats.

Uses

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.

target

EGFR

OSI-420 Preparation Products And Raw materials

Raw materials

Preparation Products

OSI-420 Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58

View Lastest Price from OSI-420 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	OSI-420 183320-51-6	US $1.00 / g	1g	99%	1ton	Career Henan Chemical Co

OSI-420
183320-51-6
US $1.00 / g
99%
Career Henan Chemical Co

OSI-420 Spectrum

OSI-420(183320-51-6)¹HNMR

183320-51-6(OSI-420)Related Search:

Erlotinib D6 HCl 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Erlotinib Impurity 35 Erlotinib Impurity 67 Erlotinib Imp.9

3,5-Dimethyl-1-adamantanol Erlotinib iMpurity 2 OSI 413 Erlotinib Impurity 20 4-Quinazolinamine,N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride(1:1)

Ethyl 3,4-dihydroxybenzoate Erlotinib Erlotinib Impurity 1 Erlotinib IMpurity C H-89 DIHYDROCHLORIDE HYDRATE

Imatinib mesylate ABT 737 Neratinib

1of4

Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride OSI-420 (DesMethyl Erlotinib,CP-473420) CP-473420 DesMethyl Erlotinib OSI-420 hydrochloride OSI-420 (DesMethyl Erlotinib) Erlotinib O-DesMethyl Metabolite IsoMer (M14) HCl 6-O-Desmethyl Erlotinib 2 OSI420/OSI-420/Desmethyl erlotinib /O-Desmethylerlotinib hydrochloride 2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride DesMethyl Erlotinib (CP-473420) HCl 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanolhydrochloride 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride Desmethyl Erlotinib (OSI-420) OSI420 HCl Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1) 7-(2&rsquo 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol 6-O-Desmethyl Erlotinib Hydrochloride DESMETHYL ERLOTINIB; CP-473420; OSI420; OSI 420; CP473420; CP 473420 2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-o Erlotinib O-Desmethyl Metabolite Isomer HCl Erlotinib O-Desmethyl Metabolite Isomer (M14) Hydrochloride O-Desmethylerlotinib hydrochloride Desmethyl Erlotinib hydrochloride OSI-420 USP/EP/BP O-Desmethylerlotinib hydrochloride salt OSI-420 (Desmethyl Erlotinib) HCl OSI-420 CP-473420 O-Desmethylerlotinib hydrochloride salt OSI420 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol hydrochloride (1:1) 183320-51-6 C21H21N3O4HCl Inhibitors