BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
- CAS No.
- 300586-90-7
- Chemical Name:
- BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
- Synonyms
- OAC1;CS-2147;OAC1, >98%;OAC1;OAC-1;BAS 00287861;OAC1;OAC-1;OAC 1;OAC1 (BAS 00287861);OAC1;OAC-1;OAC 1;BAS 00287861;iPSC Induction Enhancer II, OAC1;N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
- CBNumber:
- CB22608044
- Molecular Formula:
- C14H11N3O
- Molecular Weight:
- 237.26
- MDL Number:
- MFCD00572806
- MOL File:
- 300586-90-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H317 |
Precautionary statements | P280-P305+P351+P338 |
WGK Germany | 3 |
HS Code | 2933.99.8290 |
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- price More Price(42)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0651 | OAC1 ≥98% (HPLC) | 300586-90-7 | 5mg | $98.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 5.00501 | iPSC Induction Enhancer II, OAC1 - CAS 300586-90-7 - Calbiochem | 300586-90-7 | 25MG | $246 | 2023-01-07 | Buy |
Sigma-Aldrich | SML0651 | OAC1 ≥98% (HPLC) | 300586-90-7 | 25mg | $428 | 2022-05-15 | Buy |
TCI Chemical | O0490 | OAC1 >98.0%(GC) | 300586-90-7 | 10mg | $149 | 2024-03-01 | Buy |
TCI Chemical | O0490 | OAC1 >98.0%(GC) | 300586-90-7 | 50mg | $447 | 2024-03-01 | Buy |
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Chemical Properties,Uses,Production
Uses
OAC1 enhances iPSC reprogramming efficiency.
General Description
A cell-permeable pyrrolopyridinyl-benzamide compound that is reported to enhance the efficiency of 4F/4TF-induced iPSC generation from MEFs cultured in either feeder cell-containing ESC media or in feeder-/serum-free iSF1 media (1 μM OAC1 treatment starts 48 h after viral transduction). OCA1 is shown to increase cellular Oct4, Nanog, Sox2, and Tet1 mRNA levels via a yet unidentified mechanism, although OAC1 is reported not affect Oct4 promoter methylation, cellular Wnt signaling, or p53 and p21 mRNA levels. Six other iPSC reprogramming improving reagents, AM580, AzaC, BIX-01294 (Cat. No. 382190), Tranylcypromine (Cat. No. 616431), VPA (Cat. No. 676380), and Vitamin C (Cat. No. 1813), in comparison, do not exhibit Oct4 and Nanog promoters enhancing activity, while BIO (Cat. No. 361550) is demonstrated to be 3.8- and 6-fold less potent than OAC1, respectively, in inducing Oct4 and Nanog transcription.
Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
Biochem/physiol Actions
Cell permeable: yes
storage
+4°C
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-09-06 | BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
300586-90-7
|
US $1.00 / KG | 1KG | 95%~99% | per week 100kg | Career Henan Chemical Co |
- BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
300586-90-7
- US $1.00 / KG
- 95%~99%
- Career Henan Chemical Co