ChemicalBook >> CAS DataBase List >>2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
- CAS No.
- 1256584-73-2
- Chemical Name:
- 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
- Synonyms
- Alectinib Impurity 14;Alecensa intermediate;Alectinib intermediate A;4-Ethyl-3-iodo-α,α-dimethylbenzeneacetic acid;2-(3-Iodo-4-ethylphenyl)-2-methylpropionic acid;2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid;Benzeneacetic acid, 4-ethyl-3-iodo-α,α-dimethyl-;2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid-7;4-?Ethyl-?3-?iodo-?α,?α-?dimethylbenzeneaceti?c acid;4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
- CBNumber:
- CB22623823
- Molecular Formula:
- C12H15IO2
- Molecular Weight:
- 318.15
- MDL Number:
- MFCD22571222
- MOL File:
- 1256584-73-2.mol
- MSDS File:
- SDS
Last updated:2024-04-24 17:21:39
| Boiling point | 369.6±27.0 °C(Predicted) |
|---|---|
| Density | 1.547±0.06 g/cm3(Predicted) |
| pka | 4.32±0.11(Predicted) |
| InChI | InChI=1S/C12H15IO2/c1-4-8-5-6-9(7-10(8)13)12(2,3)11(14)15/h5-7H,4H2,1-3H3,(H,14,15) |
| InChIKey | RUVGXZCQYVEAKQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(C1=CC=C(CC)C(I)=C1)(C)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | E920550 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoicAcid | 1256584-73-2 | 10mg | $45 | 2021-12-16 | Buy |
| ChemScene | CS-M1475 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoicacid 99.25% | 1256584-73-2 | 1g | $18 | 2021-12-16 | Buy |
| ChemScene | CS-M1475 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoicacid 99.25% | 1256584-73-2 | 25g | $130 | 2021-12-16 | Buy |
| AK Scientific | 5962AQ | 2-(4-ethyl-3-iodophenyl)-2-methylpropanoicacid | 1256584-73-2 | 5g | $216.8 | 2021-12-16 | Buy |
| ChemScene | CS-M1475 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoicacid 99.25% | 1256584-73-2 | 100g | $299 | 2021-12-16 | Buy |
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Chemical Properties,Uses,Production
Uses
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
Synthesis
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid is prepared by reacting 4-Ethyl-α,α-dimethylbenzeneacetic acid with N-Iodosuccinimide in Acetic acid for 2h.
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 140)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Famo Biotech Co Ltd | +86-36680037 +86-18550473860 | mayan@famobiotech.com;sales@famobiotech.com | China | 503 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 951 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shandonghaohong biotechnology Co.,ltd. | 0635-6175299 13961496334 | sale@inyelchem.com | CHINA | 44 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
|
US $5.00 / kg | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-26 | 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
|
US $30.00 / kg | 1kg | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2023-12-29 | 2-(4-Ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd |
-
- 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
- US $30.00 / kg
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- 2-(4-Ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid-7
4-Ethyl-3-iodo-α,α-dimethylbenzeneacetic acid
4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
2-(3-Iodo-4-ethylphenyl)-2-methylpropionic acid
Alecensa intermediate
Alectinib Impurity 14
Benzeneacetic acid, 4-ethyl-3-iodo-α,α-dimethyl-
2-(4-ethyl-3-iodophenyl)-2-methylpropanoic acid
(alectinib intermediate)
4-?Ethyl-?3-?iodo-?α,?α-?dimethylbenzeneaceti?c acid
Alectinib intermediate A
1256584-73-2
1256584-73-2