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NG-25

NG-25 structure

CAS No.: 1315355-93-1

Chemical Name:: NG-25

Synonyms: NG25;3-((1H-Pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide;NG-25;NG 25; NG-25;HG-7-92-01 (NG 25);NG-25 ISO 9001：2015 REACH;NG25,MAP kinase kinase kinase, MEKK, MAPKKK,NG 25,NG-25,MAP4K,inhibit,Inhibitor,MAP3K,MAPK Kinase Kinase Kinase;N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide;N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide;Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-

CBNumber:: CB22645146

Molecular Formula:: C29H30F3N5O2

Molecular Weight:: 537.58

MDL Number:: MFCD19443255

MOL File:: 1315355-93-1.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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NG-25 Properties

Density	1.313±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMSO
form	powder
pka	12.91±0.70(Predicted)
color	white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301-H413
Precautionary statements	P273-P301+P310+P330
RIDADR	UN 2811 6.1 / PGIII

NG-25 price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1332	NG25 trihydrochloride ≥98% (HPLC)	1315355-93-1	5MG	$169	2023-06-20	Buy
Sigma-Aldrich	SML1332	NG25 trihydrochloride ≥98% (HPLC)	1315355-93-1	25MG	$676	2023-06-20	Buy
Tocris	5429	NG25 ≥98%(HPLC)	1315355-93-1	5	$325	2021-12-16	Buy
TRC	N393510	NG25	1315355-93-1	1mg	$85	2021-12-16	Buy
ChemScene	CS-0875	NG25 99.35%	1315355-93-1	1mg	$96	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML1332	5MG	$169	Buy
SML1332	25MG	$676	Buy
5429	5	$325	Buy
N393510	1mg	$85	Buy
CS-0875	1mg	$96	Buy

NG-25 Chemical Properties,Uses,Production

Uses

NG 25 inhibits TGF-beta-activated kinase 1 (TAK1). It also inhibits LYN, mitogen-activated protein kinase (MAP4K2) and Abl kinase activity.

Biochem/physiol Actions

NG25 is potent multiple kinase inhibitor belonging to type II kinase inhibitors class that binds to kinase ATP binding pocket at not ready to catalyze conformation. NG25 is used as a potent dual inhibitor of TAK1 (TGFβ-Activated Kinase 1, MAP3K7) and MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2; GCK) kinases. NG25 inhibits the activation of IKKa/IKKb and prevents the secretion of type 1 IFNs by TLR2 and TLR9 agonist.

storage

Store at -20°C

NG-25 Preparation Products And Raw materials

Raw materials

Preparation Products

NG-25 Suppliers

Global( 71)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3632	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	chaolaichem@foxmail.com	China	6870	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Shaanxi Dideu Medichem Co. Ltd	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Dideu Industries Group Limited	58
InvivoChem	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Shanghai SuperLan Chemcial Technique Centre	58

View Lastest Price from NG-25 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-20	NG-25 1315355-93-1	US $0.00-0.00 / KG	1mg	99% HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd

NG-25
1315355-93-1
US $0.00-0.00 / KG
99% HPLC
Shaanxi Dideu Medichem Co. Ltd

NG-25 Spectrum

NG-25(1315355-93-1)¹HNMR

1315355-93-1(NG-25)Related Search:

Hydroxyethyl piperazine N-Ethylacetamide 2-Aminoethyl(ethyl)amine N-Ethyl-3-methylaniline N-ethyl-pyrrolidone

N-(2-Hydroxyethyl)-2-pyrrolidone

1of2

N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide 3-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3v-(trifluoromethyl)phenyl)-4-methylbenzamide NG-25 HG-7-92-01 (NG 25) N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide NG 25; NG-25 Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)- NG-25 ISO 9001：2015 REACH NG25 3-((1H-Pyrrolo[2,3-b]pyridin-4-yl)oxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide NG25,MAP kinase kinase kinase, MEKK, MAPKKK,NG 25,NG-25,MAP4K,inhibit,Inhibitor,MAP3K,MAPK Kinase Kinase Kinase 1315355-93-1 C29H30F3N5O2 Smad TGF-beta TGF-beta/Smad