ChemicalBook >> CAS DataBase List >>CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) structure

CAS No.: 247068-81-1

Chemical Name:: CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)

Synonyms: EOS-60550;PR171 Intermediate;Kyprolis Impurity 29;Carfilzomib Impurity 33;Methanesulfonamide,N-(5-aminophenyl)-;(S)-tert-butyl 2,6-dimethyl-3-oxohept-1-en-4-ylcarbamate;tert-butyl(S)-(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate;(S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one;tert-Butyl N-[(4S)-2,6-dimethyl-3-oxohept-1-en-4-yl]carbamate;tert-butyl-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxobut-3-en-1-yl]carbamate

CBNumber:: CB22668198

Molecular Formula:: C14H25NO3

Molecular Weight:: 255.35

MDL Number:: MFCD26227261

MOL File:: 247068-81-1.mol

Last updated:2023-04-27 16:27:43

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CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Properties

Boiling point	350.4±25.0 °C(Predicted)
Density	0.964±0.06 g/cm3(Predicted)
storage temp.	2-8°C
form	Solid
pka	11.05±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P261-P305+P351+P338

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B809468	tert-Butyl((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate	247068-81-1	5g	$275	2021-12-16	Buy
AK Scientific	2987AH	(S)-tert-Butyl(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate	247068-81-1	100mg	$157	2021-12-16	Buy
ChemScene	CS-M2381	(S)-tert-Butyl(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate 97.09%	247068-81-1	10g	$203	2021-12-16	Buy
Ark Pharm	AK174320	(S)-tert-Butyl(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate 96%	247068-81-1	1g	$31	2021-12-16	Buy
ChemScene	CS-M2381	(S)-tert-Butyl(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate 97.09%	247068-81-1	5g	$136	2021-12-16	Buy

Product number	Packaging	Price	Buy
B809468	5g	$275	Buy
2987AH	100mg	$157	Buy
CS-M2381	10g	$203	Buy
AK174320	1g	$31	Buy
CS-M2381	5g	$136	Buy

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Chemical Properties,Uses,Production

Uses

tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate is an intermediate in the synthesis of (S)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt which is an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) synthesis

Synthesis of CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) from isopropenyllithium and BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

isopropenyllithium BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE 2-BROMOPROPENE

Preparation Products

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Yushan Wanfang Biotechnology Co., Ltd.	+86-025-84918180 +86-18014482516	3552541679@qq.com	China	1001	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu Feibo Pharm Technology Co., Ltd	15982321820	abby@arkpharm.com	CHINA	3279	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21149	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58

Supplier	Advantage
Nanjing Yushan Wanfang Biotechnology Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Chengdu Feibo Pharm Technology Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58

View Lastest Price from CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-01-02	(S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one 247068-81-1	US $200.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
	2019-07-06	CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) 247068-81-1	US $1.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

(S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one
247068-81-1
US $200.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)
247068-81-1
US $1.00 / KG
99%
Career Henan Chemical Co

(S)-tert-butyl 2,6-dimethyl-3-oxohept-1-en-4-ylcarbamate Carbamic acid, N-[(1S,2R)-2-hydroxy-3-methyl-1-(2-methylpropyl)-3-buten-1-yl]-, 1,1-dimethylethyl ester tert-butyl(S)-(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate Carbamic acid, [(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-butenyl]-, 1,1-dimethylethyl ester tert-butyl-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxobut-3-en-1-yl]carbamate PR171 Intermediate CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) (S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one tert-Butyl N-[(4S)-2,6-dimethyl-3-oxohept-1-en-4-yl]carbamate EOS-60550 Carfilzomib Impurity 33 Carbamic acid, N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-, 1,1-dimethylethyl ester Kyprolis Impurity 29 (1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) (1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-1,1-diMethylethyl ester Methanesulfonamide,N-(5-aminophenyl)- 247068-81-1