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GGTI 298 trifluoroacetate salt hydrate

CAS No.
1217457-86-7
Chemical Name:
GGTI 298 trifluoroacetate salt hydrate
Synonyms
GGTI-298 TFA;GGTI 298 TFA salt;GGTI298 Trifluoroacetate;WALKWJPZELDSKT-UFABNHQSSA-N;GGTI 298 trifluoroacetate salt hydrate;GGTI 298 TFA SALT;GGTI 298 (TRIFLUOROACETATE SALT);N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate
CBNumber:
CB22676894
Molecular Formula:
C29H34F3N3O5S
Molecular Weight:
593.66
MDL Number:
MFCD06409252
MOL File:
1217457-86-7.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

GGTI 298 trifluoroacetate salt hydrate Properties

Melting point 99.5-100°C
storage temp. -20°C
solubility DMSO: >20mg/mL
form film &_& lyophilized
color colorless

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

GGTI 298 trifluoroacetate salt hydrate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G5169 GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film 1217457-86-7 250μg $118 2024-03-01 Buy
Sigma-Aldrich G5169 GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film 1217457-86-7 1mg $440 2024-03-01 Buy
Cayman Chemical 16176 GGTI 298 (trifluoroacetate salt) ≥95% 1217457-86-7 500μg $106 2024-03-01 Buy
Cayman Chemical 16176 GGTI 298 (trifluoroacetate salt) ≥95% 1217457-86-7 1mg $184 2024-03-01 Buy
Cayman Chemical 16176 GGTI 298 (trifluoroacetate salt) ≥95% 1217457-86-7 5mg $816 2024-03-01 Buy
Product number Packaging Price Buy
G5169 250μg $118 Buy
G5169 1mg $440 Buy
16176 500μg $106 Buy
16176 1mg $184 Buy
16176 5mg $816 Buy

GGTI 298 trifluoroacetate salt hydrate Chemical Properties,Uses,Production

Uses

GGTI 298 trifluoroacetate salt hydrate has been used as a geranylgeranyltransferase I (GGTase I) inhibitor:

  • to study the anticancer effects of statins along with GGTI 298
  • to study its combinatorial effects with FTI-277 on statin-mediated activation of extracellular signal-regulated kinase 5 (ERK5) in the human endothelium
  • to evaluate the effect of protein geranylgeranylation (GG) inhibition on the breast cancer stem cell (CSC) population

Biochem/physiol Actions

GGTI 298 is a cell-permeable, prodrug form of the geranylgeranyltransferase I (GGTase I) inhibitor GGTI-297. It inhibits the processing of Rap 1A without effecting the processing of H-Ras.

storage

Store at -20°C

GGTI 298 trifluoroacetate salt hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Shenzhen Shengda Pharma Limited
755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33349 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4647 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55

1217457-86-7(GGTI 298 trifluoroacetate salt hydrate)Related Search:

GGTI 298 trifluoroacetate salt hydrate N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate GGTI-298 TFA GGTI298 Trifluoroacetate WALKWJPZELDSKT-UFABNHQSSA-N GGTI 298 TFA salt GGTI 298 TFA SALT;GGTI 298 (TRIFLUOROACETATE SALT) 1217457-86-7