IMiquiMod (Maleate)
- CAS No.
- 896106-16-4
- Chemical Name:
- IMiquiMod (Maleate)
- Synonyms
- IMiquiMod (Maleate)
- CBNumber:
- CB22682006
- Molecular Formula:
- C18H20N4O4
- Molecular Weight:
- 356.3758
- MDL Number:
- MFCD28168083
- MOL File:
- 896106-16-4.mol
IMiquiMod (Maleate) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B1187 | Imiquimodmaleate | 896106-16-4 | 100mg | $50 | 2021-12-16 | Buy |
| CSNpharm | CSN18539 | ImiquimodMaleate | 896106-16-4 | 250mg | $66 | 2021-12-16 | Buy |
| Crysdot | CD31000378 | Imiquimodmaleate 98+% | 896106-16-4 | 100mg | $49 | 2021-12-16 | Buy |
IMiquiMod (Maleate) Chemical Properties,Uses,Production
Uses
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19[1][2].
in vivo
In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
IC 50
TLR7; HSV-1
References
[1] Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858. DOI:10.1016/j.envres.2020.109858
[2] Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60. DOI:10.1007/s10227-001-0134-6
[3] Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46. DOI:10.1128/JVI.01196-12
[4] Michael P Sch?n, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47. DOI:10.1038/sj.jid.5700286
IMiquiMod (Maleate) Preparation Products And Raw materials
Raw materials
Preparation Products
IMiquiMod (Maleate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32281 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29772 | 58 |
View Lastest Price from IMiquiMod (Maleate) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-15 | Imiquimod maleate
896106-16-4
|
US $29.00-39.00 / mg | 99.98% | 10g | TargetMol Chemicals Inc. |
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- Imiquimod maleate
896106-16-4
- US $29.00-39.00 / mg
- 99.98%
- TargetMol Chemicals Inc.