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VER-49009

CAS No.
558640-51-0
Chemical Name:
VER-49009
Synonyms
CS-2575;CCT 129397;VER-49009(b;VER-49009;VER 49009;VER49009;5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-;VER-49009,Inhibitor,CCT-129397,CCT129397,HSP,inhibit,VER 49009,Heat shock proteins,VER49009
CBNumber:
CB22705097
Molecular Formula:
C19H18ClN3O4
Molecular Weight:
387.82
MDL Number:
MOL File:
558640-51-0.mol
Last updated:2023-05-21 10:59:17

VER-49009 Properties

Boiling point 620.2±55.0 °C(Predicted)
Density 1.379±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (257.85 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka 7.86±0.25(Predicted)

VER-49009 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13131 VER-49009 ≥98% 558640-51-0 500μg $101 2024-03-01 Buy
Cayman Chemical 13131 VER-49009 ≥98% 558640-51-0 1mg $190 2024-03-01 Buy
Cayman Chemical 13131 VER-49009 ≥98% 558640-51-0 5mg $796 2024-03-01 Buy
Cayman Chemical 13131 VER-49009 ≥98% 558640-51-0 10mg $1394 2024-03-01 Buy
TRC V756800 VER49009 558640-51-0 10mg $1485 2021-12-16 Buy
Product number Packaging Price Buy
13131 500μg $101 Buy
13131 1mg $190 Buy
13131 5mg $796 Buy
13131 10mg $1394 Buy
V756800 10mg $1485 Buy

VER-49009 Chemical Properties,Uses,Production

Uses

VER 49009 is a heat shock protein 90 (HSP90) inhibitor. VER 49009 causes induction of HSP72 and HSP27 alongside depletion of client proteins, including C-RAF, B-RAF, and survivin, and the protein arginine methyltransferase PRMT5.

Definition

ChEBI: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine. It has a role as a Hsp90 inhibitor. It is a member of pyrazoles, a member of resorcinols, a member of monochlorobenzenes, a monomethoxybenzene and an aromatic amide.

VER-49009 Preparation Products And Raw materials

Raw materials

Preparation Products

VER-49009 Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Henan Alfa Chemical Co., Ltd
+8618339805032 alfa4@alfachem.cn China 12755 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4121 55
5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide CCT 129397 VER-49009;VER 49009;VER49009 CS-2575 1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)- VER-49009,Inhibitor,CCT-129397,CCT129397,HSP,inhibit,VER 49009,Heat shock proteins,VER49009 VER-49009(b 558640-51-0