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3-Methyl-2-butanone structure
Chemical Name:
MIPK;iso-C3H7COCH3;3-Methyl-2-but;Methylbutanone;2-Acetopropane;2-Acetylpropane;3-Methylbutanone;3-Ketoisopentane;Methyl-2-butanone;Methyl butanone-2
Molecular Formula:
Formula Weight:
MOL File:

3-Methyl-2-butanone Properties

Melting point:
−92 °C(lit.)
Boiling point:
94-95 °C(lit.)
0.805 g/mL at 25 °C(lit.)
vapor pressure 
53.33 hPa (19.9 °C)
refractive index 
n20/D 1.388(lit.)
Flash point:
6 °C
storage temp. 
Flammables area
water: soluble8.21g/L at 20°C
Clear colorless
explosive limit
Water Solubility 
6 g/L (20 ºC)
Exposure limits
TLV-TWA 700 mg/m3 (200 ppm); STEL 875 mg/m3 (250 ppm) (ACGIH).
CAS DataBase Reference
563-80-4(CAS DataBase Reference)
NIST Chemistry Reference
2-Butanone, 3-methyl-(563-80-4)
EPA Substance Registry System
2-Butanone, 3-methyl-(563-80-4)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F
Risk Statements  11-67
Safety Statements  9-16-33
RIDADR  UN 2397 3/PG 2
WGK Germany  1
RTECS  EL9100000
Autoignition Temperature 475 °C
Hazard Note  Highly Flammable
HazardClass  3
PackingGroup  II
HS Code  29141990
Toxicity LD50 orally in male mice: 29.86 mmol/kg (Tanii)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

3-Methyl-2-butanone price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 537721 3-Methyl-2-butanone 99% 563-80-4 250ml $55.3 2018-11-13 Buy
Sigma-Aldrich 537721 3-Methyl-2-butanone 99% 563-80-4 1l $148 2018-11-13 Buy
TCI Chemical M0173 3-Methyl-2-butanone >99.0%(GC) 563-80-4 25mL $15 2018-11-22 Buy
TCI Chemical M0173 3-Methyl-2-butanone >99.0%(GC) 563-80-4 500mL $47 2018-11-22 Buy
Alfa Aesar B24527 3-Methyl-2-butanone, 98% 563-80-4 250ml $37.5 2018-11-13 Buy

3-Methyl-2-butanone Chemical Properties,Uses,Production

Chemical Properties


Chemical Properties

MIPK is a colorless liquid with an acetonelike odor.


Methyl isopropyl ketone (MIPK) is used asa solvent for lacquers.


Solvent for nitrocellulose lacquers.

General Description

A colorless liquid with a pleasant odor. Flash point below 70°F. Less dense than water. May be toxic by inhalation and skin absorption. Used as a solvent.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Ketones, such as 3-Methyl-2-butanone, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.


Toxic material. Embryo/fetal damage andneonatal toxicity.

Health Hazard

Irritating to the eyes, nose, throat, upper respiratory tract, and skin.

Health Hazard

The acute toxic effects from exposure to thevapors of MIPK are narcosis and irritationof the eyes, skin, and respiratory passages.In rabbits the irritation effect of 100 mg fora 24-hour exposure was mild in the eyes,while 500 mg was moderate on the skin. Thetoxicity data on this compound are too scant.In general, its toxicity is low and narcosissymptoms in humans may be felt only at veryhigh concentrations. In guinea pigs exposureto 5000 ppm caused coma.

Fire Hazard

Special Hazards of Combustion Products: Acrid smoke and fumes

Safety Profile

Poison by ingestion. Mildly toxic by inhalation and skin contact. Mutation data reported. A skin and eye irritant. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes.

Potential Exposure

This ketone is used as a solvent for nitrocellulose lacquers.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit


UN23973-Methylbutan-2-one, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Reflux the ketone with a little KMnO4. Fractionate it through a spinning-band column, dry with CaSO4 and distil it. [Beilstein 1 IV 3287.]


Vapors may form explosive mixture with air. Ketones are incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, nitrated amines, azo, diazo, azido compounds, carbamates, organic cyanates

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

3-Methyl-2-butanone Preparation Products And Raw materials

Raw materials

Preparation Products

3-Methyl-2-butanone Suppliers

Global( 190)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
career henan chemical co
+86-371-86658258 CHINA 20516 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20094 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4660 58
(323) 306-3136
(626) 453-0409 United States 8409 58
Jinan Jason Pharmaceutical Co., Ltd. 0531-82956131 15069164249
0531-82956625 China 1526 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40277 62
INTATRADE GmbH +49 3493/605464
+49 3493/605470 Germany 3580 66

View Lastest Price from 3-Methyl-2-butanone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 3-Methyl-2-butanone
US $1.00 / kg 1kg 95%-99% as request career henan chemical co

3-Methyl-2-butanone Spectrum

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