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DIPHENYLCYCLOPROPENONE

DIPHENYLCYCLOPROPENONE
DIPHENYLCYCLOPROPENONE structure
CAS No.
886-38-4
Chemical Name:
DIPHENYLCYCLOPROPENONE
Synonyms
886-38-4;opropenone;Diphencyprone;RARECHEM AQ C3 0050;Diphencyclopropenone;α,β-Carbonylstilbene;iphenylcyclopropenone;DIPHENYLCYCLOPROPENONE;Cyclopropenone, diphenyl-;2,3-Diphenylcyclopropenone
CBNumber:
CB2289953
Molecular Formula:
C15H10O
Formula Weight:
206.24
MOL File:
886-38-4.mol

DIPHENYLCYCLOPROPENONE Properties

Melting point:
118-122 °C (lit.)
Boiling point:
305.09°C (rough estimate)
Density 
1.232
refractive index 
1.6324 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
color 
Slightly pinkish-orange to beige
Merck 
14,3308
BRN 
608049
InChIKey
HCIBTBXNLVOFER-UHFFFAOYSA-N
CAS DataBase Reference
886-38-4(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
I7G14NW5EC
NCI Drug Dictionary
diphencyprone
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280-P261-P280g-P302+P352a-P321-P333+P313-P501a
Hazard Codes  Xi
Risk Statements  38-43
Safety Statements  36/37
WGK Germany  3
HS Code  29142990

DIPHENYLCYCLOPROPENONE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 500 mg $30.71 2021-12-16 Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 1 g $49.58 2021-12-16 Buy
Sigma-Aldrich 177377 Diphenylcyclopropenone 98% 886-38-4 1g $51.1 2021-12-16 Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 5 g $168.35 2021-12-16 Buy
Sigma-Aldrich 177377 Diphenylcyclopropenone 98% 886-38-4 5g $193 2021-12-16 Buy

DIPHENYLCYCLOPROPENONE Chemical Properties,Uses,Production

Description

Diphencyprone is a potent contact allergen responsible for occupational contact dermatitis in chemists and dermatological staff.

Description

Diphencyprone (DCP) is a contact sensitizing agent. Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10). It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v. Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta. Formulations containing DCP have been used in the treatment of alopecia areta.

Chemical Properties

slightly pinkish-orange to beige crystalline

Definition

ChEBI: A cyclopropenone compound having phenyl substituents at the 2- and 3-positions.

Contact allergens

Diphencyprone is a potent contact allergen used in topical immunotherapy to treat some severe alopecia areata. It is responsible for occupational contact dermatitis in chemists and dermatology department staff

Purification Methods

Crystallise it from cyclohexane. UV (MeCN): max 226, 282, 297nm. [Beilstein 17 IV 1736.]

DIPHENYLCYCLOPROPENONE Preparation Products And Raw materials

Raw materials

Preparation Products


DIPHENYLCYCLOPROPENONE Suppliers

Global( 137)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Anhui Royal Chemical Co., Ltd.
+86-025-86655873
marketing@royal-chem.com CHINA 536 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
TopScience Biochemical
00852-68527855
00852-26406298 info@itopbiochem.com China Hong Kong 904 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37441 58

View Lastest Price from DIPHENYLCYCLOPROPENONE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-06 DIPHENYLCYCLOPROPENONE
886-38-4
US $1.00 / kg 1kg 95%-99% 100kg Career Henan Chemical Co

DIPHENYLCYCLOPROPENONE Spectrum


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