ChemicalBook >> CAS DataBase List >>Diethyl pyrocarbonate
Diethyl pyrocarbonate
- CAS No.
- 1609-47-8
- Chemical Name:
- Diethyl pyrocarbonate
- Synonyms
- DEPC;DIETHYL DICARBONATE;Ethyl pyrocarbonate;DKD;Piref;Baycovin;DEP／DEPC;ethylpyrocarbonate;Diethylpyrokarbonat;iethylpyrocarbonate
- CBNumber:
- CB2300384
- Molecular Formula:
- C6H10O5
- Molecular Weight:
- 162.14
- MDL Number:
- MFCD00009106
- MOL File:
- 1609-47-8.mol
- MSDS File:
- SDS
Last updated:2024-03-26 14:13:49
| Melting point | 69℃ |
|---|---|
| Boiling point | 93-94 °C18 mm Hg(lit.) |
| Density | 1.12 g/mL at 20 °C |
| refractive index |
n |
| Flash point | 157 °F |
| storage temp. | 2-8°C |
| solubility | 95% ethanol: soluble4.5g/10 mL, clear, colorless |
| form | Liquid |
| color | APHA: ≤20 |
| Water Solubility | slow decomposition |
| Sensitive | Moisture Sensitive |
| Merck | 14,7998 |
| BRN | 637031 |
| Stability | Combustible. Unstable - readily decomposes. Incompatible with strong oxidizing agents, strong acids, strong reducing agents, strong bases, ammonia. |
| InChIKey | FFYPMLJYZAEMQB-UHFFFAOYSA-N |
| LogP | 1.101 (est) |
| CAS DataBase Reference | 1609-47-8(CAS DataBase Reference) |
| FDA 21 CFR | 189.140 |
| Substances Added to Food (formerly EAFUS) | DIETHYL PYROCARBONATE-- PROHIBITED |
| EWG's Food Scores | 1 |
| FDA UNII | LMR3LZG146 |
| NIST Chemistry Reference | Diethyl pyrocarbonate(1609-47-8) |
| EPA Substance Registry System | Dicarbonic acid, diethyl ester (1609-47-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LQ9350000 | |||||||||
| F | 4.4-9-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29209085 | |||||||||
| Toxicity | LD50 orally in Rabbit: 850 mg/kg | |||||||||
| NFPA 704 |
|
Diethyl pyrocarbonate price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.41751 | Diethyl dicarbonate for synthesis | 1609-47-8 | 5ml | $35.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.41751 | Diethyl dicarbonate for synthesis | 1609-47-8 | 25mL | $130 | 2024-03-01 | Buy |
| Sigma-Aldrich | 298711 | Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. | 1609-47-8 | 25g | $159 | 2024-03-01 | Buy |
| Sigma-Aldrich | 3660-OP | OmniPur DEPC - CAS 1609-47-8 - Calbiochem | 1609-47-8 | 25g | $269 | 2024-03-01 | Buy |
| Sigma-Aldrich | 298711 | Diethyl Pyrocarbonate - CAS 1609-47-8 - Calbiochem Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. | 1609-47-8 | 100g | $547 | 2024-03-01 | Buy |
Diethyl pyrocarbonate Chemical Properties,Uses,Production
Chemical Properties
liquid
Uses
Modification reagent for His and Tyr residues in proteins. Robust probe for structural disruptions in dsDNA, reacting with fully or partially unstacked bases.1
Uses
Diethyl pyrocarbonate may be used in the following studies:
- For the modification of histidyl residues in proteins.
- As a nuclease inhibitor, for the extraction of undegraded nucleic acids from etiolated and green plant tissues.
- For the modification of linear and supercoiled plasmid DNAs.
- As a chemical probe to investigate the secondary structure in negatively supercoiled DNA.
- For cabethoxylation of histidine residues of actin.
Uses
Gentle esterifying agent. Preservative for wines, soft drinks, fruit juices.
Definition
ChEBI: The diethyl ester of dicarbonic acid.
General Description
Diethyl pyrocarbonate (DEP) is a bactericidal agent and decomposes in water to CO2 and ethanol. DEP inhibits enzymes such as DNase and RNase without affecting nucleic acids. It is useful for the preparation of mRNA from tissues.
Biochem/physiol Actions
Inactivates RNase in solution at about 0.1% (v/v), thus protecting RNA against degradation.
Safety Profile
Poison by ingestion, inhalation, and intraperitoneal routes. Concentrated DEPC is irritating to eyes, mucous membranes, and sh. When heated to decomposition it emits acrid smoke and fumes. See also ESTERS.
Purification Methods
Dissolve the ester in Et2O, wash it with dilute HCl, H2O, dry over Na2SO4, filter, evaporate and distil the residue first in vacuo then at atmospheric pressure. It is soluble in alcohols, esters, ketones and hydrocarbon solvents. A 50% w/w solution is usually prepared for general use. Treat with great CAUTION as DEP irritates the eyes, mucous membranes and skin. [Boehm & Mehta Chem Ber 71 1797 1938, Thoma & Rinke Justus Liebigs Ann Chem 624 30 1959, Beilstein 3 IV 18.]
Diethyl pyrocarbonate Preparation Products And Raw materials
Global( 375)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Hebei Yibangte Import and Export Co. , Ltd. | +86-0311-85030958 +8615532196582 | lisa@yibangte.com | China | 2988 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from Diethyl pyrocarbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-26 | Diethyl pyrocarbonate
1609-47-8
|
US $0.00-0.00 / KG | 1KG | 99% | 50000KG | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2024-03-26 | Diethyl pyrocarbonate
1609-47-8
|
US $0.00-0.00 / kg | 1kg | 99% | 50000kg | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2023-08-30 | Diethyl pyrocarbonate
1609-47-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Diethyl pyrocarbonate
1609-47-8
- US $0.00-0.00 / KG
- 99%
- Hebei Yibangte Import and Export Co. , Ltd.
-
- Diethyl pyrocarbonate
1609-47-8
- US $0.00-0.00 / kg
- 99%
- Hebei Yibangte Import and Export Co. , Ltd.
-
- Diethyl pyrocarbonate
1609-47-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
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Factory supply high quality Diethyl pyrocarbonate CAS 1609-47-8 with good price
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