ChemicalBook >> CAS DataBase List >>4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
![4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Structure](CAS/20180713/GIF/1577222-14-0.gif)
- CAS No.
- 1577222-14-0
- Chemical Name:
- 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
- Synonyms
- ALKS-8700;diroximel fumarate;Diroximel Fumarete;Diroximel Fumarete(ALKS-8700);Diroximel Fumarate DR Pellets;5-dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774);2-(2,5-dioxopyrrolidin-1-yl)ethyl (E)-4-chloro-4-oxobut-2-enoate;4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
- CBNumber:
- CB23070732
- Molecular Formula:
- C11H13NO6
- Molecular Weight:
- 255.22
- MDL Number:
- MFCD28502263
- MOL File:
- 1577222-14-0.mol
Last updated:2023-05-18 11:31:12
| Melting point | 96 - 99°C |
|---|---|
| Boiling point | 441.0±25.0 °C(Predicted) |
| Density | 1.319±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | -1.60±0.20(Predicted) |
| color | White to Off-White |
| FDA UNII | K0N0Z40J3W |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29111 | Diroximel Fumarate | 1577222-14-0 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 1577222-14-0 | 50mg | $553 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 1577222-14-0 | 10mg | $143 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 1577222-14-0 | 25mg | $336 | 2024-03-01 | Buy |
| AK Scientific | 6016DW | Diroximelfumarate | 1577222-14-0 | 50mg | $714 | 2021-12-16 | Buy |
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Chemical Properties,Uses,Production
Description
Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.
Uses
Diroximel Fumarate is a novel oral fumarate in development for the treatment of patients with relapsing forms of multiple sclerosis.
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 87)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 7838 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate pictures](https://img.chemicalbook.com/ProductImageEN/2020-10/Small/592b448a-abae-4688-9744-3dd819d91270.png) |
2021-01-06 | 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
1577222-14-0
|
US $1.00 / KG | 1KG | MIn98%HPLC/LC | 100KGS | Career Henan Chemica Co |
-
- 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
1577222-14-0
- US $1.00 / KG
- MIn98%HPLC/LC
- Career Henan Chemica Co
1577222-14-0(4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate)Related Search:
(2E)-2-Butenedioic acid 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester
2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate
4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
ALKS-8700
diroximel fumarate
DiroximelFumarete,ALKS-8700,4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester
5-dioxopyrrolidin-1-yl)ethyl methyl fumarate
DIROXIMEL FUMARATE; ALKS8700; ALKS 8700; ALKS-8700;2-(2;5-DIOXOPYRROLIDIN-1-YL)ETHYL METHYL FUMARATE
Diroximel Fumarete(ALKS-8700)
(E)-but-2-enedioic acid 2-(2,5-dioxo-pyrrolidin-1-yl)ethyl ester methyl ester
2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774)
Diroximel Fumarete
Diroximel Fumarate DR Pellets
Inhibitor,Diroximel,ALKS-8700,ALKS 8700,ALKS8700,BIIB 098,Diroximel fumarate,inhibit,BIIB098,BIIB-098
2-(2,5-dioxopyrrolidin-1-yl)ethyl
(E)-4-chloro-4-oxobut-2-enoate
1577222-14-0
API