ChemicalBook >> CAS DataBase List >>1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
- CAS No.
- 203866-14-2
- Chemical Name:
- 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
- Synonyms
- N-BOC-TRANS-4-FLUORO-L-PROLINE;N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID;Boc-trans-4-F-Pro-OH;Boc-trans-4-fluoro-Pro-OH;BOC-TRANS-4-FLUORO-L-PROLINE;N-Boc-Tran-4-Fluoro-L-proline;1-BOC-Trans-4-fluoro-L-proline;(2R,4S)-N-BOC-4-FLUORO-D-PROLINE;N-T-BOC-TRANS-4-FLUORO-L-PROLINE;(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
- CBNumber:
- CB2312240
- Molecular Formula:
- C10H16FNO4
- Molecular Weight:
- 233.24
- MDL Number:
- MFCD06796085
- MOL File:
- 203866-14-2.mol
Last updated:2023-04-27 16:27:43
| Melting point | 115-119°C |
|---|---|
| Boiling point | 346.0±42.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| refractive index | -69 ° (C=1, MeOH) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.53±0.40(Predicted) |
| color | White to Almost white |
| optical activity | [α]22/D -65.0±5°, c = 1 in chloroform |
| InChIKey | YGWZXQOYEBWUTH-RQJHMYQMSA-N |
| CAS DataBase Reference | 203866-14-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 687332 | N-Boc-trans-4-fluoro-L-proline 97% | 203866-14-2 | 500mg | $84 | 2024-03-01 | Buy |
| TCI Chemical | B3177 | (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid >96.0%(GC)(T) | 203866-14-2 | 1g | $198 | 2024-03-01 | Buy |
| TCI Chemical | B3177 | (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid >96.0%(GC)(T) | 203866-14-2 | 200mg | $59 | 2024-03-01 | Buy |
| Alfa Aesar | H27721 | N-Boc-trans-4-fluoro-L-proline, 98% | 203866-14-2 | 250mg | $71.8 | 2021-12-16 | Buy |
| Alfa Aesar | H27721 | N-Boc-trans-4-fluoro-L-proline, 98% | 203866-14-2 | 1g | $180 | 2021-12-16 | Buy |
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.
Synthesis of 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate from BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 203)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PRISUN PHARMATECH CO.,LTD | +86-021-54326183-8001 +8618917565227 | prisun@prisunpharma.com | China | 215 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +8618068193575 | sales4@btcpharm.com | China | 254 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-26 | BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
|
US $0.00-0.00 / kg | 1kg | 98% | Kgs | BTC Nantong Pharmaceuticals Technology Co.,Ltd | |
 |
2023-03-17 | BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
|
US $43.00 / kg | 1kg | 99% | 5000 tons | Hebei Duling International Trade Co. LTD | |
 |
2021-07-13 | BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
- US $0.00-0.00 / kg
- 98%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
-
- BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
- US $43.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
-
- BOC-TRANS-4-FLUORO-L-PROLINE
203866-14-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
203866-14-2(1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate)Related Search:
Nr
(2R,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid
(2R,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid
N-BOC-cis-4-fluoro-L-proline
Cbz-D-Valine
1of3
N-T-BOC-TRANS-4-FLUORO-L-PROLINE
N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE
BOC-TRANS-4-FLUORO-L-PROLINE
(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected
trans-4-Fluoro-L-proline, N-BOC protected
(2S,4R)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid
(2R,4S)-N-BOC-4-FLUORO-D-PROLINE
(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected
(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid
N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline
(2S,4R)-4-FLUORO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
(2R,4S)-N-Boc-trans-4-Fluoro-D-proline methyl ester
(2R,4S)-N-Boc-trans-4-Fluoro-D-proline
N-Boc-Tran-4-Fluoro-L-proline
Boc-trans-4-fluoro-Pro-OH
(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid
N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline
N-Boc-trans-4-fluoro-L-proline
1-BOC-Trans-4-fluoro-L-proline
(2S,4R)-1-Boc-4-fluoropyrrolidine-2-carboxylic acid
(2S,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboyxlic acid
(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
(2S,4R)-4-Fluoro-1,2-pyrrolidinedicarboxylic Acid tert-B
utyl Ester
trans-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylicacid
1,2-Pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
(2S,4R)-N-Boc-4-fluoropyrrolidine-2-carboxy lic acid
(2S,4R)-1-(tert-Dutoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid
(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid >
(2S,4R)-4-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylicaci
BOC-TRANS-4-FLUORO-L-PROLINE USP/EP/BP
TIANFU CHEM --BOC-TRANS-4-FLUORO-L-PROLINE
N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID
N-BOC-TRANS-4-FLUORO-L-PROLINE
Boc-trans-4-F-Pro-OH
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
1-(tert-Butyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
203866-14-2
Carboxylic Acids (Chiral)
Chiral Building Blocks
Synthetic Organic Chemistry
Chiral Building Blocks
Heterocyclic Building Blocks
Pyrrolidines