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Propargyl-PEG6-acid

CAS No.
1951438-84-8
Chemical Name:
Propargyl-PEG6-acid
Synonyms
CAS_1951438-84-8;Propargyl-PEG6-acid;Propargyl-PEG5-C2-COOH;Propyne-PEG5-CH2CH2COOH;Propargyl-PEG5-CH2CH2COOH;Propargyl-PEG6-Propionic Acid;4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid;Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid
CBNumber:
CB23134212
Molecular Formula:
C16H28O8
Molecular Weight:
348.39
MDL Number:
MFCD28950778
MOL File:
1951438-84-8.mol
Last updated:2024-04-07 18:44:46

Propargyl-PEG6-acid Properties

Boiling point 462.8±45.0 °C(Predicted)
Density 1.126±0.06 g/cm3(Predicted)
refractive index n/D 1.469
storage temp. -20°C
solubility Soluble in Water
form liquid
pka 4.28±0.10(Predicted)

SAFETY

Risk and Safety Statements

Propargyl-PEG6-acid price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 902667 Propargyl-PEG6-acid 1951438-84-8 250mg $482 2024-03-01 Buy
Sigma-Aldrich 902667 Propargyl-PEG6-acid 1951438-84-8 1g $1240 2023-06-20 Buy
Activate Scientific AS104184 Propargyl-PEG5-CH2CH2COOH 95+% 1951438-84-8 5G $1478 2021-12-16 Buy
Apolloscientific BIPG1707 Propargyl-PEG6-acid 1951438-84-8 100mg $507 2021-12-16 Buy
Activate Scientific AS104184 Propargyl-PEG5-CH2CH2COOH 95+% 1951438-84-8 1g $583 2021-12-16 Buy
Product number Packaging Price Buy
902667 250mg $482 Buy
902667 1g $1240 Buy
AS104184 5G $1478 Buy
BIPG1707 100mg $507 Buy
AS104184 1g $583 Buy

Propargyl-PEG6-acid Chemical Properties,Uses,Production

Description

Propargyl-PEG6-acid comprises propargyl and carboxylic acid functional groups. The acid group reacts with primary amines in the presence of activators (e.g. EDC, or HATU).The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The molecule has good solubility in aqueous environment.

Uses

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Propargyl-PEG6-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
airuikechemical co., ltd.
+undefined86-15315557071 sales02@airuikechemical.com China 994 58
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from Propargyl-PEG6-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propargyl-peg6-acid pictures 2024-04-07 Propargyl-peg6-acid
1951438-84-8
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
Propargyl-PEG6-acid pictures 2024-03-26 Propargyl-PEG6-acid
1951438-84-8
US $0.00 / g 1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
  • Propargyl-PEG6-acid pictures
  • Propargyl-PEG6-acid
    1951438-84-8
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
Propargyl-PEG6-acid Propyne-PEG5-CH2CH2COOH Propargyl-PEG5-CH2CH2COOH CAS_1951438-84-8 4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid Propargyl-PEG6-Propionic Acid Propargyl-PEG5-CH2CH2COOH/4,7,10,13,16,19-Hexaoxadocos-21-ynoic acid Propargyl-PEG5-C2-COOH 1951438-84-8 peg