ChemicalBook >> CAS DataBase List >>(1R,2S,3S)-Aprepitant
(1R,2S,3S)-Aprepitant
- CAS No.
- 172822-28-5
- Chemical Name:
- (1R,2S,3S)-Aprepitant
- Synonyms
- SM001F;(2S,3S,1’R)-Aprepitant;Aretetan Impurity-(RSS);Aprepitant (R,S,S)-Isomer;Aprepitant Impurity - (RSS);(R,S,S)-Enantiomer Aprepitant;Aprepitant Impurity 6(R,S,S-Isomer);Aprepitant Intermediate Impurity -(RSS);Aprepitant impurity 7/(1R,2S,3S)-Aprepitant;5-([(2S,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
- CBNumber:
- CB23146512
- Molecular Formula:
- C23H21F7N4O3
- Molecular Weight:
- 534.43
- MDL Number:
- MOL File:
- 172822-28-5.mol
Last updated:2024-06-11 18:14:38
(1R,2S,3S)-Aprepitant Chemical Properties,Uses,Production
Uses
(2S,3S,1’R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1’R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs.
(1R,2S,3S)-Aprepitant Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 39)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | sale@hdimpurity.com | China | 3389 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 5056 | 50 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
View Lastest Price from (1R,2S,3S)-Aprepitant manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-20 | Aprepitant Impurity 22
172822-28-5
|
US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD |
- Aprepitant Impurity 22
172822-28-5
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
172822-28-5((1R,2S,3S)-Aprepitant)Related Search:
Aprepitant
5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
Benzyl dihydrogen phosphate
(2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
Aprepitant Impurity 19
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
Fosaprepitant Impurity 6
Aprepitant
ent-Aprepitant
1of4
Aretetan Impurity-(RSS)
5-([(2S,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
3H-1,2,4-Triazol-3-one, 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-, [2S-[2α(S*),3β]]- (9CI)
SM001F
(2S,3S,1’R)-Aprepitant
Aprepitant Impurity - (RSS)
Aprepitant Intermediate Impurity -(RSS)
Aprepitant impurity 7/(1R,2S,3S)-Aprepitant
Aprepitant Impurity 6(R,S,S-Isomer)
(R,S,S)-Enantiomer Aprepitant
Aprepitant (R,S,S)-Isomer
3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
172822-28-5