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METHACHOLINE CHLORIDE

METHACHOLINE CHLORIDE
METHACHOLINE CHLORIDE structure
CAS No.
62-51-1
Chemical Name:
METHACHOLINE CHLORIDE
Synonyms
amechol;mecholyl;Methacloline;MECHOLYL CHLORIDE;Mecholine chloride;methylacetylcholine;Methacoline chloride;METHACHOLINE CHLORIDE;methacholiniumchloride;MethacholineChloride>
CBNumber:
CB2316248
Molecular Formula:
C8H18ClNO2
Formula Weight:
195.69
MOL File:
62-51-1.mol

METHACHOLINE CHLORIDE Properties

Melting point:
171-173 °C(lit.)
Density 
1.1028 (rough estimate)
refractive index 
1.5790 (estimate)
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL, clear, colorless
form 
powder
PH
3.0~7.0 (50g/l, 25℃)
Water Solubility 
almost transparency
Merck 
14,5940
BRN 
4162373
Stability:
Unstable - moisture sensitive. Incompatible with oxidizing agents.
CAS DataBase Reference
62-51-1
FDA UNII
0W5ETF9M2K
EPA Substance Registry System
1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride (62-51-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P264-P270-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501-P301+P312+P330-P305+P351+P338-P261
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  BR5250000
3-10-21
HS Code  29239000

METHACHOLINE CHLORIDE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2251 Acetyl-β-methylcholine chloride ≥98% (TLC), powder 62-51-1 25g $132 2021-03-22 Buy
Sigma-Aldrich A2251 Acetyl-β-methylcholine chloride ≥98% (TLC), powder 62-51-1 100g $437 2021-03-22 Buy
TCI Chemical M0073 Methacholine Chloride >98.0%(T) 62-51-1 25g $71 2021-03-22 Buy
TCI Chemical M0073 Methacholine Chloride >98.0%(T) 62-51-1 500g $684 2021-03-22 Buy
Cayman Chemical 23092 Acetyl-β-methylcholine (chloride) ≥95% 62-51-1 5g $29 2021-03-22 Buy

METHACHOLINE CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

colourless to white crystalline powder with a slight

Uses

antihypertensive, antianginal

General Description

Methacholine chloride occurs as colorless or white crystalsor as a white crystalline powder. It is odorless or has aslight odor and is very deliquescent. It is freely soluble inwater, alcohol, or chloroform, and its aqueous solution isneutral to litmus and bitter. It is hydrolyzed rapidly in alkalinesolutions. Solutions are relatively stable to heat and willkeep for at least 2 or 3 weeks when refrigerated to delaygrowth of molds.

Clinical Use

Methacholine, acetyl β-methylcholine, is marketed as the racemic mixture. It is a selective muscarinic agonist with very little activity at nicotinic receptors. Although methacholine chloride is marketed as the racemic mixture, the S-(+)-enantiomer is 240-fold more potent than the R-(–)-isomer at muscarinic receptors. In addition, AChE hydrolyzes S-(+)–methacholine at approximately 54% the rate of acetylcholine, whereas the R-(–)–enantiomer is a weak inhibitor. Methacholine chloride is used via inhalation for the diagnosis of asthma. The resulting bronchospasm may be relieved with bronchodilators. Methacholine chloride is available as a powder that is reconstituted for inhalation.

Purification Methods

It forms white hygroscopic needles from Et2O and is soluble in H2O, EtOH and CHCl3. It decomposes readily in alkaline solutions and slowly in H2O. It should be handled and stored in a dry atmosphere. The bromide is less hygroscopic, and the picrate has m 129.5-131o (from EtOH). [racemate: Annis & Ely Biochem J 53 34 1953, IR of iodide: Hansen Acta Chem Scand 13 155 1959, Beilstein 4 IV 1670.]

METHACHOLINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products


METHACHOLINE CHLORIDE Suppliers

Global( 123)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9664 58
Zhengzhou Alfa Chemical Co.,Ltd
+8613343822234 +86-0371-55052911
sales5@alfachem.cn;sales9@alfachem.cn;sale1@alfachem.cn China 11995 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58
Dayang Chem (Hangzhou) Co.,Ltd.
17705817739 +86-571-88938639
+86-571-88938652,+86-571- 88492614 info@dycnchem.com CHINA 52932 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58
Chemwill Asia Co.,Ltd. 86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23975 58
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 400-660-8290 21-61259100-
86-21-61259102 sh@meryer.com China 40264 62

View Lastest Price from METHACHOLINE CHLORIDE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-28 METHACHOLINE CHLORIDE USP/EP/BP
62-51-1
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited

METHACHOLINE CHLORIDE Spectrum


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