Equol
- CAS No.
- 531-95-3
- Chemical Name:
- Equol
- Synonyms
- Equol;(S)-EQUOL;R,S-EQUOL;S,R-equol;(3S)-Equol;(-)-(S)-EQUOL;Equol USP/EP/BP;EQUOL, (+/-)-(SH);(S)-Equol,99%e.e.;4',7-ISOFLAVANDIOL
- CBNumber:
- CB2317528
- Molecular Formula:
- C15H14O3
- Molecular Weight:
- 242.27
- MDL Number:
- MFCD00200962
- MOL File:
- 531-95-3.mol
- MSDS File:
- SDS
| Melting point | 189-190°C |
|---|---|
| alpha | D -21.5° |
| Boiling point | 312.25°C (rough estimate) |
| Density | 1.1914 (rough estimate) |
| refractive index | 1.5557 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Soluble), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.94±0.40(Predicted) |
| color | White to Pale Yellow |
| CAS DataBase Reference | 531-95-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 2T6D2HPX7Q |
| NCI Drug Dictionary | S-equol |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| F | 3-10 |
Equol price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10010173 | (S)-Equol ≥98% | 531-95-3 | 1mg | $21 | 2024-03-01 | Buy |
| Cayman Chemical | 10010173 | (S)-Equol ≥98% | 531-95-3 | 5mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 10010173 | (S)-Equol ≥98% | 531-95-3 | 10mg | $157 | 2024-03-01 | Buy |
| Cayman Chemical | 10010173 | (S)-Equol ≥98% | 531-95-3 | 25mg | $341 | 2024-03-01 | Buy |
| Tocris | 6158 | (S)-Equol ≥98%(HPLC) | 531-95-3 | 10 | $122 | 2021-12-16 | Buy |
Equol Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Uses
A human urinary metabolite of Daidzein. It is also a natural estrogenic metabolite from soy isoflavones
Uses
serine protease
Uses
Receptor; binding activity
Uses
(S)-Equol and R-Equol are metabolites of the soy isoflavones Daidzein (D103500) and Genistein. Both have significant biological actions.
Definition
ChEBI: Equol is a member of hydroxyisoflavans.
Biological Activity
equol is an isoflavan produced by intestinal bacteria in response to soy isoflavone intake in human. it shows a wide range of activities including antioxidant activity, anti-inflammation activity and anticancer activity. it is reported that equol specifically binds to 5α-dht and has a modest affinity for recombinant estrogen receptor erβ, which may be responsible for most of equol’s biological properties. [1]
in vitro
in vitro studies were conducted to measure both the binding affinity of equol for 5alpha-dihydrotestosterone (5alpha-dht) and the effects of equol treatment in human prostate cancer (lncap) cells. it was found that equol bound to 5alpha-dht with maximum and half maxim concentrations of 100 nm and 4.8 nm, respectively. in addition, equol significantly offset the increases in psa levels from lncap cells. [1]
in vivo
an in vivo study was performed to investigate effects of equol on rat prostate weight and circulating levels of sex steroid hormones. 1.0 mg/kg of equol was injected to long-evans rats fed with a low isoflavone diet for 25 days. findings from this study suggested that equol significantly decreased rat prostate weights and down-regulated serum levels of 5alpha-dht. however, this agent did not alter levels of lh, testosterone and estradiol. [1]
References
[1]lund td, blake c, bu l, hamaker an, lephart ed. iequol an isoflavonoid: potential for improved prostate health, in vitro and in vivo evidence. reprod biol endocrin. 2011; 9(4): doi: 10.1186/1477-7827-9-4.
[2]setchell dr and clerici c. equol: pharmacokinetics and biological actions. j nutr. 2010 jul; 140(7): 1363s–8s.
Equol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Kaitian Chemical Co., LTD | +undefined13337835376 | kt_chem@126.com | China | 40 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
View Lastest Price from Equol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | Equol; Soybean extract
531-95-3
|
US $0.00 / KG | 1KG | >99% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2023-09-19 | Equol
531-95-3
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2023-04-11 | Equol
531-95-3
|
US $0.00-0.00 / kg | 1kg | 99% | 2 tons | Nanjing Kaitian Chemical Co., LTD |
-
- Equol; Soybean extract
531-95-3
- US $0.00 / KG
- >99% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Equol
531-95-3
- US $0.00-0.00 / kg
- 0.99
- Hebei Yibangte Import and Export Co. , Ltd.
-
- Equol
531-95-3
- US $0.00-0.00 / kg
- 99%
- Nanjing Kaitian Chemical Co., LTD