ChemicalBook >> CAS DataBase List >>Troxerutin

Troxerutin

CAS No.
7085-55-4
Chemical Name:
Troxerutin
Synonyms
Troxerutine;Venoruton;Troxerutin CRS;RUVEN;Z-6000;Qucrutin;Rufen P-4;VASTRIBIL;POSORUTIN;Troxrutin
CBNumber:
CB2317568
Molecular Formula:
C33H42O19
Molecular Weight:
742.68
MDL Number:
MFCD00893813
MOL File:
7085-55-4.mol
MSDS File:
SDS
Last updated:2024-03-07 16:58:36

Troxerutin Properties

Melting point 181°C
Boiling point 1058.4±65.0 °C(Predicted)
Density 1.65±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Freely soluble in water, slightly soluble in ethanol (96 per cent) and practically insoluble in methylene chloride.
pka 5.92±0.40(Predicted)
color Light Yellow to Yellow
Merck 14,9789
BRN 4778232
InChIKey KMPBUGGPUQOWMJ-NXPSPVSKSA-N
CAS DataBase Reference 7085-55-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 7Y4N11PXO8
ATC code C05CA04,C05CA54

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Safety Statements  22-24/25
WGK Germany  3
RTECS  LK8331500
HS Code  2938100000

Troxerutin price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000497 Troxerutin European Pharmacopoeia (EP) Reference Standard 7085-55-4 y0000497 $220 2024-03-01 Buy
Sigma-Aldrich PHR2815 Troxerutin certified reference material, pharmaceutical secondary standard 7085-55-4 50MG $365 2024-03-01 Buy
TCI Chemical T3541 Troxerutin >90.0%(HPLC) 7085-55-4 5g $52 2024-03-01 Buy
TCI Chemical T3541 Troxerutin >90.0%(HPLC) 7085-55-4 25g $154 2024-03-01 Buy
Cayman Chemical 27220 Troxerutin 7085-55-4 10g $55 2024-03-01 Buy
Product number Packaging Price Buy
Y0000497 y0000497 $220 Buy
PHR2815 50MG $365 Buy
T3541 5g $52 Buy
T3541 25g $154 Buy
27220 10g $55 Buy

Troxerutin Chemical Properties,Uses,Production

Chemical Properties

Yellow Powder

Originator

Venoruton,Novartis Co

Uses

vasoprotectant

Uses

Used in the treatment of venous disorders

Uses

Troxerutin, a derivative of the naturally occurring bioflavonoid rutin, is thought to inhibit red cell and platelet aggregation, improve erythrocyte deformability, and improve plasma viscosity retinal microcirculation. A double-blind randomized clinical trial compared troxerutin with placebo in 27 patients with CRVO. The limitations of the study included a small number of patients and short follow-up time.

Manufacturing Process

In a nitrogen atmosphere 120 g of caustic soda (3 moles) in solution are added to 610 g of rutin (1 mol) suspended in 2 litres of water, the mixture being vigorously agitated by a mechanical stirrer, 241.5 g of ethylene chlorohydrin being then introduced at 55°C for 10 min. When all the chlorohydrin has been thus added the temperature is progressively raised to 75°C and maintained at this level for 2 hours. After cooling, in a nitrogen atmosphere, the pH value adjusted to 5 by the addition of dilute hydrochloric acid. The solution is kept in an ice box for 24 hours and then filtered to remove any impurities. At reduced pressure the solution is evaporated until dry, the residue taken up in 3 litres of boning methanol which dissolves the tri-(β-hydroxyethyl)rutin formed and leaves the sparingly soluble sodium chloride behind. The tri-(β-hydroxyethyl)rutin is recovered from its methanolic solution either by evaporation and refrigeration, or by evaporation precipitation with absolute ethanol. In either case tri-(β-hydroxyethyl)rutin obtained is in the form of small very hygroscopic crystals which contain alcohol of crystallization.These crystals are quickly shaken washed in a little cold absolute ethanol and then dried in vacuum at 100°C. 680 g of anhydrous tri-(β-hydroxyethyl)rutin are thus obtained in the form of a yellow powder which melts at 156°C.GB Patent No. 833,174; April 21, 1960; Assigned to Zyma S.A., a Swiss Corporation, of Route Etraz, Nyon Canton of Vaud, Switzerland

Therapeutic Function

Topical venotonic

target

VEGFR | Wnt/β-catenin | NF-kB | SOD | PI3K | Akt

Troxerutin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 406)Suppliers
Supplier Tel Email Country ProdList Advantage
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
+86-029-86185165 +8618629664246 guoyuan@eastchinapharm.com China 1600 58
Chengdu ChenLv Herb Co.,Ltd
+undefined13608205856 maryextract@126.com China 127 58
Wuhan Boyuan Import & Export Co., LTD
+86-15175982296 15175982296; Mike@whby-chem.com China 983 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5960 58
Shaanxi Haibo Biotechnology Co., Ltd
+86-02963020060 +86-18629295024 hibo06@xaltbio.com China 1000 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14770 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479 sales@fine-chemtech.com CHINA 885 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55

View Lastest Price from Troxerutin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Troxerutin pictures 2024-03-16 Troxerutin
7085-55-4
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
 Troxerutin  pictures 2024-03-07 Troxerutin
7085-55-4
US $100.00-50.00 / kg 1kg 99% 20000tons Liaoning Pharmaceutical Innovation Co., Ltd
Troxerutin pictures 2024-03-01 Troxerutin
7085-55-4
US $10.00 / kg 1kg DAB1999,EP9 10000 Changsha Staherb Natural Ingredients Co., Ltd.
  • Troxerutin pictures
  • Troxerutin
    7085-55-4
  • US $0.00 / KG
  • 98%+
  • WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
  •  Troxerutin  pictures
  • Troxerutin
    7085-55-4
  • US $100.00-50.00 / kg
  • 99%
  • Liaoning Pharmaceutical Innovation Co., Ltd
  • Troxerutin pictures
  • Troxerutin
    7085-55-4
  • US $10.00 / kg
  • DAB1999,EP9
  • Changsha Staherb Natural Ingredients Co., Ltd.
3μ,4μ,7-Tris[O-(2-hydroxyethyl)]rutin, Troxerutin Troxerutin,Trihydroxyethylrutin 3',4',7-Tris(hydroxyethyl)rutin 3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside Factor-P-zyma 2-[3,4-BIS(2-HYDROXYETHOXY)PHENYL]-3-[[6-O-(6-O-DEOXY-A-L-MANNOPYRANOSYL)-BETA-D-GLUCOPYRANOSYL]OXY]-5-HYDROXY-7-(2-HYDROXYETHOXY)-4H-1-BENZOPYRAN-4-ONE Trihydroxylrutin Trihydroxyethylrutoside Trioxyethylrutin 2-[3,4-Bis(2-hydroxethoxy)phenyl]-3-[[6-O-(6-O-deoxy-a-L-mannopyranosyl)-B-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one, Posorutin, Ruven, Vastribil, 4H-1-Benzopyran-4-one, 2-3,4-bis(2-hydroxyethoxy)phenyl-3-6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyloxy-5-hydroxy-7-(2-hydroxyethoxy)- VITAMIN P4 (TROXERUTIN) 7,3’,4’-tris[O-(2-hydroxyethyl)]rutin Tris(hydroxyethyl)rutin Tris(hydroxyethyl)rutoside Rufen P-4 Venoruton P-4 Z-6000 TROXERUTIN(P) 2-[3,4-Bis(2-hydroxethoxy)phenyl]-3-[[6-O-(6-O-deoxy-α-L-Mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one Trihydroxyethylrutin, 3',4',7-Tris[O-(2-hydroxyethyl)]rutin 4H-1-Benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)- Hydroxyetbylrutin TROXERUTIN TRIHYDROXYETHYLRUTIN VASTRIBIL RUVEN POSORUTIN 3',4',7-TRIS-O-(2-HYDROXYETHYL)RUTIN 2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxymethyl]-2-oxanyl]oxy]-1-benzopyran-4-o Tris-O-(2-hydroxyethyl)rutin Trihydroxyethylrutin, CP Troxerutin (85%) 2-(3,4-Bis(2-hydroxyethoxy)phenyl)-5-hydroxy-7-(2-hydroxyethoxy)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one Troxerutin USP/EP/BP Natural Sophora Japonica Extract 98% CAS?7085-55-4?Troxerutin Natural Herbal Extract Troxerutin (CAS 7085-55-4) Qucrutin TroxerutinQ: What is Troxerutin Q: What is the CAS Number of Troxerutin Q: What is the storage condition of Troxerutin Q: What are the applications of Troxerutin Venoruton Troxerutine Troxerutin CRS QuKe rutin Trihydroxyethylrutin Troxerutin-P OT15980 OT-15980 Troxrutin 7085-55-4 C33H42O19 Natural Dyes BioChemical Biochemicals and Reagents Intermediates & Fine Chemicals Pharmaceuticals Natural Plant Extract Miscellaneous Natural Products Inhibitors Plant extracts Herb extract POSORUTIN