Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Structure
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate structure
CAS No.
1421312-36-8
Chemical Name:
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Synonyms
ROXA-022;RSYY(Roxadustat)-20;Roxadustat Impurity 9;Roxadustat Impurities4;Roxadustat Methyl Ester;Roxadustat Methy Ester Impurity;methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate;methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate;N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine methyl ester;Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, methyl ester
CBNumber:
CB23358234
Molecular Formula:
C20H18N2O5
Molecular Weight:
366.37
MDL Number:
MFCD34184479
MOL File:
1421312-36-8.mol
Request For Quotation

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Chemical Properties,Uses,Production

Uses

Roxadustat Methyl Ester is used in the preparation of Roxadustat.Roxadustat (H948180) is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.It is used for treatment of anemia in patient with chronic kidney disease.

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate synthesis

1421312-35-7
5680-79-5
1421312-36-8
Synthesis of methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate from methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate and Glycine methyl ester hydrochloride

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Preparation Products And Raw materials

Raw materials

ROXA-016 methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate 5-Phenoxy-1,3-isobenzofurandione 4-Nitrophthalonitrile 4-PHENOXYPHTHALONITRILE
methyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester 4-phenoxy-1,2-benzenedicarboxylic acid FG-4592 interMediate Methanol
Glycine methyl ester hydrochloride

1of3

Preparation Products

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Suppliers

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
Shanghai Innopharm Industrial Co., Ltd. 		+86-21-59960785 +86-17701845089 sales@hoyaopharm.com China 261 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8613627253706 sale@hdimpurity.com China 1504 58
Shanghai Famo Biotech Co Ltd 		+86-36680037 +86-18550473860 mayan@famobiotech.com;sales@famobiotech.com China 503 58
NEW SANITARY INTERNATIONAL LIMITED 15502117565 02117565@163.com China 395 58
Jiangsu Vcare PharmaTech Co., Ltd. 025-58741518; 18013018875 sales@vcarepharmatech.com China 308 61
Shanghai Famo Bio-chemical Technology Company Ltd. +862136680027 15800370750 sales@famobiotech.com China 504 56
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Supplier Advantage
career henan chemical co 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shanghai Innopharm Industrial Co., Ltd. 		58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		58
Shanghai Famo Biotech Co Ltd 		58
NEW SANITARY INTERNATIONAL LIMITED 58
Jiangsu Vcare PharmaTech Co., Ltd. 61
Shanghai Famo Bio-chemical Technology Company Ltd. 56
ChemStrong Scientific Co.,Ltd 56
Shanghai Kewel Chemical Co., Ltd. 50

View Lastest Price from methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate pictures 2019-09-05 methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
1421312-36-8
 US $5.50 / KG 2KG 96%-99% 100kg Career Henan Chemical Co

1421312-36-8(methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate)Related Search:

6-BROMO-3 H-ISOBENZOFURAN-1-ONE methyl 7-bromo-4-hydroxyisoquinoline-3-carboxylate methyl2-(chloromethyl)-4-phenoxybenzoate methyl 4-hydroxy-6-phenoxyisoquinoline-3-carboxylate 4-Aminophthalimide
Roxadustat 5-Aminophthalide 1(3H)-Isobenzofuranone, 5-phenoxy- INDEX NAME NOT YET ASSIGNED FG-4592 interMediate

1of2

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate ROXA-022 Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, methyl ester Roxadustat Impurity 9 Roxadustat Methyl Ester methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate Roxadustat Impurities4 Roxadustat Impurity 2Q: What is Roxadustat Impurity 2 Q: What is the CAS Number of Roxadustat Impurity 2 RSYY(Roxadustat)-20 N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine methyl ester Roxadustat Methy Ester Impurity 1421312-36-8