t-Boc-N-Amido-PEG4-propargyl

CAS No.
1219810-90-8
Chemical Name:
t-Boc-N-Amido-PEG4-propargyl
Synonyms
Propargyl-PEG4-NHBoc;Boc-N-Amido-PEG4-Alkyne;Propargyl-PEG5-Boc Amine;t-Boc-N-Amido-PEG4-propargyl;tert-butyl (3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate;tert-butylN-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate;5,8,11,14-Tetraoxa-2-azaheptadec-16-ynoic acid, 1,1-dimethylethyl ester;tert-butyl N-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl]carbamate;Propargyl-PEG4-NHBoc/5,8,11,14-Tetraoxa-2-azaheptadec-16-ynoic acid, 1,1-dimethylethyl ester
CBNumber:
CB23364017
Molecular Formula:
C16H29NO6
Molecular Weight:
331.4
MDL Number:
MFCD30182022
MOL File:
1219810-90-8.mol
Last updated:2025-07-16 16:28:12
Product description Number Pack Size Price
t-Boc-N-Amido-PEG4-propargyl 98% BP-23288 500mg $680
Propargyl-PEG4-NHBoc 97% B-1345 1g $458.3
tert-butyl3,6,9,12-tetraoxapentadec-14-yn-1-ylcarbamate 95%-98% 10-3127 1g $600

t-Boc-N-Amido-PEG4-propargyl Properties

Boiling point 426.0±40.0 °C(Predicted)
Density 1.054±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
solubility Soluble in DMSO, DCM, DMF
form Liquid
pka 12.23±0.46(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

t-Boc-N-Amido-PEG4-propargyl price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23288 t-Boc-N-Amido-PEG4-propargyl 98% 1219810-90-8 500mg $680 2021-12-16 Buy
Acrotein B-1345 Propargyl-PEG4-NHBoc 97% 1219810-90-8 1g $458.3 2021-12-16 Buy
Abosyn 10-3127 tert-butyl3,6,9,12-tetraoxapentadec-14-yn-1-ylcarbamate 95%-98% 1219810-90-8 1g $600 2021-12-16 Buy
Product number Packaging Price Buy
BP-23288 500mg $680 Buy
B-1345 1g $458.3 Buy
10-3127 1g $600 Buy

t-Boc-N-Amido-PEG4-propargyl Chemical Properties,Uses,Production

Description

t-Boc-N-Amido-PEG4-propargyl is a propargyl linker with one side protected by Boc group. The propargyl group can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The Boc protected amine can be deprotected under mild acidic conditions.

Uses

Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-N-Amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG4-propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

t-Boc-N-Amido-PEG4-propargyl Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39035 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 1924344760@confluore.cn China 2997 58
Compound Net Biotechnology Inc.
+8615303909093 sales@compound-net.com China 2914 58
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
Changzhou Hopschain Chemical Co.,Ltd. 0519-85528066 13775048983 sales@hopschem.com China 31553 55
Jinan elephant international trading co., LTD 13006575422@163.com China 6355 58
Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28785 58

View Lastest Price from t-Boc-N-Amido-PEG4-propargyl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-N-Amido-PEG4-propargyl pictures 2025-07-16 Boc-N-Amido-PEG4-propargyl
1219810-90-8
US $159.00-42.00 / mg 10g TargetMol Chemicals Inc.
Propargyl-PEG4-NHBoc pictures 2025-06-07 Propargyl-PEG4-NHBoc
1219810-90-8
US $0.00 / g 5g >98.00% 5g Xian confluore Biological Technology Co., Ltd.

t-Boc-N-Amido-PEG4-propargyl Spectrum

t-Boc-N-Amido-PEG4-propargyl Boc-N-Amido-PEG4-Alkyne Propargyl-PEG4-NHBoc tert-butyl (3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate tert-butylN-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamate Propargyl-PEG5-Boc Amine Propargyl-PEG4-NHBoc/5,8,11,14-Tetraoxa-2-azaheptadec-16-ynoic acid, 1,1-dimethylethyl ester 5,8,11,14-Tetraoxa-2-azaheptadec-16-ynoic acid, 1,1-dimethylethyl ester tert-butyl N-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl]carbamate 1219810-90-8 SiChem