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SPHINGOSYLPHOSPHORYLCHOLINE

SPHINGOSYLPHOSPHORYLCHOLINE structure

CAS No.: 1670-26-4

Chemical Name:: SPHINGOSYLPHOSPHORYLCHOLINE

Synonyms: SPC;MGC119002;D-ERYTHRO-SPC;Lyso SM (d18:1);LYSO-SPHINGOMYELIN;urocortin 3 (stresscopin);Lyso-Sphingomyelin (d18:1);SPHINGOSYLPHOSPHORYLCHOLINE;spingosyl-phosphorylcholine;Sphingenyl-1-phosphorylcholine

CBNumber:: CB2356664

Molecular Formula:: C23H49N2O5P

Molecular Weight:: 464.62

MDL Number:: MFCD02259287

MOL File:: 1670-26-4.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:13

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SPHINGOSYLPHOSPHORYLCHOLINE Properties

Melting point	90-102°C
storage temp.	-20°C
solubility	chloroform/methanol (2:1): complete10 mg/ml, clear to slightly hazy, colorless to light yellow
form	powder
color	light yellow
BRN	7342520

SAFETY

Risk and Safety Statements

WGK Germany	3
F	1-8-10

SPHINGOSYLPHOSPHORYLCHOLINE price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	10007947	Lyso-Sphingomyelin (d18:1) ≥98%	1670-26-4	1mg	$90	2024-03-01	Buy
Cayman Chemical	10007947	Lyso-Sphingomyelin (d18:1) ≥98%	1670-26-4	5mg	$401	2024-03-01	Buy
Sigma-Aldrich	S4257	Sphingosylphosphoryl-choline ≥98%, powder	1670-26-4	10mg	$332	2024-03-01	Buy
Sigma-Aldrich	S4257	Sphingosylphosphoryl-choline ≥98%, powder	1670-26-4	25mg	$473.4	2024-03-01	Buy
Sigma-Aldrich	567735	Sphingosylphosphoryl-choline	1670-26-4	10mg	$535	2024-03-01	Buy

Product number	Packaging	Price	Buy
10007947	1mg	$90	Buy
10007947	5mg	$401	Buy
S4257	10mg	$332	Buy
S4257	25mg	$473.4	Buy
567735	10mg	$535	Buy

SPHINGOSYLPHOSPHORYLCHOLINE Chemical Properties,Uses,Production

Chemical Properties

Yellowish Waxy Solid

Uses

Lyso SM (d18:1) has been used:

to study its effect on the skeletal muscle ryanodine receptor (RyR1), in the presence and absence of calmodulin through single channel recordings in planar lipid bilayers
as an inhibitor of Ca²⁺sensor calmodulin (CaM)
as a standard in circular dichroism (CD) spectroscopy to determine lipid selectivity of the lipid-peptide interactions

Uses

Neurotrophic effects of Sphingosylphosphorylcholine were studied in cerebellar granule neurons of mice and PC-12 cells.

Uses

Involved in cell regulation, and transmembrane signaling. A putative lipid second messenger, connected via Protein Kinase C to the phosphatidylinositol-derived second messengers for signal transduction.

Definition

ChEBI: Sphingosine-1-phosphocholine is a phosphosphingolipid consisting of sphingosine having a phosphocholine moiety attached to its primary hydroxyl group. It is a phosphosphingolipid, a member of phosphocholines and an ammonium betaine. It is functionally related to a sphingosine. It is a conjugate base of a sphingosylphosphocholine acid and a sphingosine-1-phosphocholine(1+).

General Description

Lyso SM (d18:1), also known as sphingosylphosphorylcholine (SPC), is a bioactive lipid molecule. This lysophospholipid is present in normal blood plasma, ascites and various tissues.

Biochem/physiol Actions

Sphingosylphosphorylcholine (SPC) is a bioactive lipid that mediates intracellular and extracellular signaling. It mobilizes Ca2+ from intracellular stores via an IP3-independent pathway. It stimulates the production of CCL2 that may contribute to development of atherosclerosis. SPC is a ligand for endothelial differentiation gene receptor 3 (EDG3).

SPHINGOSYLPHOSPHORYLCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

SPHINGOSYLPHOSPHORYLCHOLINE Suppliers

Global( 69)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chemson Industrial (Shanghai) Co., Ltd.	86-21-65208861- 8007	sales1@chemson.com.cn	CHINA	117	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50

Supplier	Advantage
Chemson Industrial (Shanghai) Co., Ltd.	58
career henan chemical co	58
AFINE CHEMICALS LIMITED	58
Alfa Chemistry	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chemsky（shanghai）International Co.,Ltd.	50

View Lastest Price from SPHINGOSYLPHOSPHORYLCHOLINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	SPHINGOSYLPHOSPHORYLCHOLINE 1670-26-4	US $1.00 / KG	1KG	98%-99.9%	200kg	Career Henan Chemical Co

SPHINGOSYLPHOSPHORYLCHOLINE
1670-26-4
US $1.00 / KG
98%-99.9%
Career Henan Chemical Co

1670-26-4(SPHINGOSYLPHOSPHORYLCHOLINE)Related Search:

SPHINGOSYLPHOSPHORYLCHOLINE N-OCTADECANOYLSPHING-OSYLPHOSPHORYLCHOLINE 6-((N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-HEXANOYL)SPHINGOSYL PHOSPHOCHOLINE SPHINGOMYELIN (BOVINE), [CHOLINE METHYL-14C] N-ACETYL-SPHINGOSYLPHOSPHORYLCHOLINE

N-DODECANOYL-NBD-SPHINGOSYLPHOSPHORYLCHOLINE,N-C12-NBD-SPHINGOSYLPHOSPHORYLCHOLINE Sphingosylphosphorylcholine?(lyso-sphingomyelin),Sphingosylphosphorylcholine?(lyso-sphingomyelin) SPHINGOMYELIN AZIDOPHOSPHORYLSPHINGOSYLCHOLINE 3-O-TERT-BUTYLDIMETHYLSILYL-D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE

LYSOSPHINGOMYELIN, [CHOLINE METHYL-3H] N-Palmitoyl-1-13C-Sphingosylphosphorylcholine N-HEPTADECANOYL-SPHINGOSYLPHOSPHORYLCHOLINE SPHINGOSYLPHOSPHORYLCHOLINE CHLORIDE N-BOC-[N-3-O-ISOPROPYLIDENE]-D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE

N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine N-(12-((1-pyrenesulfonyl)amido)dodecanoyl)sphingosylphosphorylcholine L-THREO-SPHINGOSYLPHOSPHORYLCHOLINE

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LYSO-SPHINGOMYELIN D-ERYTHRO-SPC D-ERYTHRO-SPHINGOSYLPHOSPHORYLCHOLINE SPHINGOSYLPHOSPHORYLCHOLINE SPHINGOSYLPHOSPHORYLCHOLINE, D-ERYTHRO 2-[[[(2-amino-3-hydroxy-4-octadecenyl)oxy]hydroxy-phosphinyl]oxy]-n,n,n-trimethylethanaminium inner salt (2S,3R,4E)-2-Amino-4-octadecene-3-hydroxy-1-phosphocholine D-erythro-Sphingosine phosphocholine Lyso SM (d18:1) Anti-UCN3 antibody produced in goat MGC119002 urocortin 3 (stresscopin) SPHINGOSYLPHOSPHORYLCHOLINE;LYSO SM (D18:1) D-erythro-Sphingosylphosphorylcholine (Synthetic) 2-[[[[(2S,3R,4E)-2-AMino-3-hydroxy-4-octadecen-1-yl]oxy]hydroxyphosphinyl]oxy]-N,N,N-triMethyl-ethanaMiniuM Sphingenyl-1-phosphorylcholine spingosyl-phosphorylcholine Lysosphingomyelin, 2-[[[(2-Amino-3-hydroxy-4-octadecenyl)oxy]hydroxy-phosphinyl]oxy]-N,N,N-trimethylethanaminium inner salt SPC Sphingosylphosphoryl-choline - CAS 1670-26-4 - Calbiochem Lyso-Sphingomyelin (d18:1) D-erythro Lysosphingomyelin (d18:1) 1670-26-4 C23H49N2O5P Lipids Phosphosphingolipids Sphingolipids Ceramide phosphocholines (sphingomyelins) BioChemical Biochemicals and Reagents Activators Fatty Acid Derivatives & Lipids Glycerols Inhibitors Protein Kinase Inhibitors and Activators Chemical Activators