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Vinflunine

Vinflunine
Vinflunine structure
CAS No.
162652-95-1
Chemical Name:
Vinflunine
Synonyms
VINFLUNINE;Vinflunine Tartrate;Vinflunine 162652-95-1;20',20'-Difluoro-3',4'-dihydrovinorelbine;4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine;4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine
CBNumber:
CB2358406
Molecular Formula:
C45H54F2N4O8
Formula Weight:
816.93
MOL File:
162652-95-1.mol

Vinflunine Properties

Density 
1.39±0.1 g/cm3(Predicted)
pka
11.36±0.60(Predicted)
CAS DataBase Reference
162652-95-1(CAS DataBase Reference)
FDA UNII
5BF646324K
NCI Dictionary of Cancer Terms
vinflunine

Vinflunine Chemical Properties,Uses,Production

Description

Vinflunine (also referred to as PM391) is a semisynthetic analog of the natural vinca alkaloids vinblastine and vincristine that was approved by the European Medicines Agency (EMEA) in 2009 for the treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regimen. Vinflunine is synthesized from anhydrovinblastine in a superacid media (HF-SbF5) and in the presence of a chlorinated solvent like CHCl3 or CCl4.

Originator

Pierre Fabre (France)

Definition

ChEBI: An organic heteropentacyclic compound and an organic heterotetracyclic compound that is vinorelbine in which the tetrahydropyridine moiety of the heterotetracyclic part of the molecule has been redced to the corresponding piperidine, and in which the ethy group attached to this ring has been replaced by a 1,1-difluoroethyl group.

brand name

Javlor

Vinflunine Preparation Products And Raw materials

Raw materials

Preparation Products


Vinflunine Suppliers

Global( 79)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21837 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 10157 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
0086 13815430202
sale02@cqherb.com CHINA 362 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17852 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58

View Lastest Price from Vinflunine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-17 Vinflunine 162652-95-1
162652-95-1
US $30.00 / mg 20mg ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
2019-08-05 Vinflunine
162652-95-1
US $1.00 / KG 1KG 95%-99% 2000kg career henan chemical co
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