5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide
- CAS No.
- 1189426-07-0
- Chemical Name:
- 5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide
- Synonyms
- [2H11]-Glipizide;5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide;Glipizide d11Q: What is Glipizide d11 Q: What is the CAS Number of Glipizide d11 Q: What is the storage condition of Glipizide d11 Q: What are the applications of Glipizide d11
- CBNumber:
- CB23595596
- Molecular Formula:
- C21H16D11N5O4S
- Molecular Weight:
- 456.602959558
- MDL Number:
- MFCD08705009
- MOL File:
- 1189426-07-0.mol
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 30074 | Glipizide-d11 | 1189426-07-0 | 500μg | $153 | 2024-03-01 | Buy |
Cayman Chemical | 30074 | Glipizide-d11 | 1189426-07-0 | 1mg | $290 | 2024-03-01 | Buy |
TRC | G410227 | Glipizide-d11 | 1189426-07-0 | 1mg | $145 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006543 | GLIPIZIDE-D11 95.00% | 1189426-07-0 | 1MG | $721.88 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006543 | GLIPIZIDE-D11 95.00% | 1189426-07-0 | 10MG | $1732.5 | 2021-12-16 | Buy |
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide Chemical Properties,Uses,Production
Description
Glipizide-d11 is intended for use as an internal standard for the quantification of glipizide by GC- or LC-MS. Glipizide is a hypoglycemic agent. It inhibits ATP-sensitive potassium (KATP) channels in primary mouse pancreatic β cells (IC50 = 6.4 nM). Glipizide induces insulin release from isolated rat pancreatic tissue with an EC50 value of 40 nM. Dietary administration of glipizide (5 mg/kg per day for 10 days) increases the number of insulin receptors on isolated and purified mouse liver plasma membranes. It reduces plasma glucose and triglyceride, but not total cholesterol, levels and increases plasma insulin levels in a rat model of diabetes induced by a high-fat diet and streptozotocin (STZ; ) when administered orally at a dose of 5 mg/kg. Formulations containing glipizide have been used in the treatment of type 2 diabetes.
Uses
Labelled Glipizide (G410225). A sulfonylurea hypoglycemic agent. Used as an antidiabetic.
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | 3004208264@qq.com | China | 3022 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
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TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31130 | 58 |
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HX Pharmaceutical technology co., LTD | 15671363360 | 494267389@qq.com | China | 2908 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12582 | 58 |