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U-73343

U-73343 Structure
U-73343 structure
CAS No.
142878-12-4
Chemical Name:
U-73343
Synonyms
U-73343;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-;U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
CBNumber:
CB2377935
Molecular Formula:
C29H42N2O3
Molecular Weight:
466.66
MDL Number:
MFCD00211221
MOL File:
142878-12-4.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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U-73343 Properties

Boiling point 641.5±55.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
storage temp. +15C to +30C
solubility ethanol: 0.93 mg/mL
pka 10.68±0.40(Predicted)
form powder
color white
Stability Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
FDA UNII S2C4J8704C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

U-73343 price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich U6881 U-73343 142878-12-4 1mg $167 2024-03-01 Buy
Sigma-Aldrich 662041 U-73343 142878-12-4 5mg $172 2024-03-01 Buy
Cayman Chemical 17339 U-73343 ≥95% 142878-12-4 1mg $32 2024-03-01 Buy
Cayman Chemical 17339 U-73343 ≥95% 142878-12-4 5mg $93 2024-03-01 Buy
Sigma-Aldrich U6881 U-73343 142878-12-4 5mg $309 2024-03-01 Buy
Product number Packaging Price Buy
U6881 1mg $167 Buy
662041 5mg $172 Buy
17339 1mg $32 Buy
17339 5mg $93 Buy
U6881 5mg $309 Buy

U-73343 Chemical Properties,Uses,Production

Description

U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3?Cell permeable.

Uses

U-73343 is an inactive structural analog of U-73122.

General Description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at RT

References

1) Bleasdale?et al. (1990),?Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils; J. Pharmacol. Exp. Ther.,?255?756 2) Morley?et al. (1992),?A new, nongenomic estrogen action: the rapid release of intracellular calcium; Endocrinology,131?1305 3) Muto?et al. (1997),?The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell; J. Pharmacol. Exp. Ther.,?282?1379

U-73343 Preparation Products And Raw materials

Raw materials

Preparation Products

U-73343 Suppliers

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 905 64
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
InvivoChem 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Sigma-Aldrich 80
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58

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U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE 1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE U-73343 1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione 3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene U73343, U-73343, U 73343 U-73343 - CAS 142878-12-4 - Calbiochem 2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]- U-73343,Inhibitor,U73343,Phospholipase,inhibit 142878-12-4 APIS