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PHENAMIL

PHENAMIL structure

CAS No.: 2038-35-9

Chemical Name:: PHENAMIL

Synonyms: PHENAMIL;phenylamil;phenamil methanesulfonate salt;Phenamil methanesulfonate (free base);3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide;3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-;3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide

CBNumber:: CB2384179

Molecular Formula:: C12H12ClN7O

Molecular Weight:: 305.72

MDL Number:: MFCD00210211

MOL File:: 2038-35-9.mol

Last updated:2023-07-12 17:02:16

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PHENAMIL Properties

Melting point	>181°C (dec.)
Density	1.65±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >15 mg/mL
form	solid
pka	8.10±0.46(Predicted)
color	yellow

SAFETY

Risk and Safety Statements

WGK Germany	3

PHENAMIL price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	3379	Phenamil ≥99%(HPLC)	2038-35-9	50	$353	2021-12-16	Buy
Usbiological	145690	Phenamil	2038-35-9	10mg	$325	2021-12-16	Buy
American Custom Chemicals Corporation	API0008629	PHENAMIL 95.00%	2038-35-9	5MG	$254.1	2021-12-16	Buy
American Custom Chemicals Corporation	API0008629	PHENAMIL 95.00%	2038-35-9	25MG	$863.48	2021-12-16	Buy

Product number	Packaging	Price	Buy
3379	50	$353	Buy
145690	10mg	$325	Buy
API0008629	5MG	$254.1	Buy
API0008629	25MG	$863.48	Buy

PHENAMIL Chemical Properties,Uses,Production

Uses

Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte

Definition

ChEBI: Phenylamil is a member of pyrazines and a member of guanidines.

Enzyme inhibitor

This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility.

PHENAMIL Preparation Products And Raw materials

Raw materials

Preparation Products

PHENAMIL Suppliers

Global( 28)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Jinan Yaoyan Pharmaceutical Co., Ltd.		jnyaoyan@163.com	China	3069	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai EFE Biological Technology Co., Ltd.	58
Jinan Yaoyan Pharmaceutical Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	58
Changzhou Furuisi Biotechnology Co., Ltd	58

2038-35-9(PHENAMIL)Related Search:

phenamil receptor PHENAMIL METHANESULFONATE 5-AMINOPYRAZINE-2-CARBOXAMIDE PHENAMIL 6-CHLORO-2-PYRAZINECARBOXAMIDE

2-pyrazinoylguanidine 2-amino-3-chloro-5-methyl-pyrazine 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE 2,6-Pyrazinediamine(9CI) 3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE

PHENAMIL METHANESULFONATE 5-(N,N-HEXAMETHYLENE)-AMILORIDE 2-Amino-5-chloropyrazine (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE 3-AMINO-N-METHYLPYRAZINE-2-CARBOXAMIDE

2-Chloro-6-methylpyrazine

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PHENAMIL 3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE 3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt phenamil methanesulfonate salt phenylamil 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide 3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide 3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide 3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide Phenamil methanesulfonate (free base) 2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]- 2038-35-9 C12H12ClN7OCH3SO3H C12H12ClN7O Irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride. Cell Biology Cell Signaling and Neuroscience BioChemical Amiloride and Derivatives Monovalent Ion Channels Ion Channels Sodium Channel Modulators Voltage-gated Ion Channels