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4-Hexanolide

CAS No.
695-06-7
Chemical Name:
4-Hexanolide
Synonyms
2(3H)-Furanone, 5-ethyldihydro-;γ-Hexalactone;GAMMA-HEXALACTONE;5-Ethyldihydro-2(3H)-furanone;GAMMA-CAPROLACTONE;5-Ethyldihydrofuran-2(3H)-one;hexan-4-olide;Dihydro-5-ethyl-2(3H)-furanone;FEMA 2556;g-Hexanolactone
CBNumber:
CB2387024
Molecular Formula:
C6H10O2
Molecular Weight:
114.14
MDL Number:
MFCD00005401
MOL File:
695-06-7.mol
MSDS File:
SDS
Last updated:2024-08-21 22:41:43

4-Hexanolide Properties

Melting point -18°C
Boiling point 219 °C(lit.)
Density 1.023 g/mL at 25 °C(lit.)
vapor pressure 2.4hPa at 20℃
FEMA 2556 | GAMMA-HEXALACTONE
refractive index n20/D 1.439(lit.)
Flash point 209 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
Specific Gravity 1.023
color Colorless to Almost colorless
Odor at 10.00 % in dipropylene glycol. herbal coconut sweet coumarin tobacco
Odor Type tonka
Water Solubility 77g/L at 20℃
JECFA Number 223
BRN 107260
LogP 0.3 at 20℃
CAS DataBase Reference 695-06-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) GAMMA-HEXALACTONE
EWG's Food Scores 1
FDA UNII .GAMMA.-HEXALACTONE (J16NAT1G41)
1,1'-ADIPOYLBISAZIRIDINE (80LAI0N8O4)
NIST Chemistry Reference 2(3H)-Furanone, 5-ethyldihydro-(695-06-7)
EPA Substance Registry System 2(3H)-Furanone, 5-ethyldihydro- (695-06-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-36
Safety Statements  26-36
WGK Germany  2
RTECS  LU4220000
Hazard Note  Irritant
TSCA  Yes
HS Code  29322090
NFPA 704
1
0 0

4-Hexanolide price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W255611 γ-Hexalactone natural,97%,FG 695-06-7 100g $702 2024-03-01 Buy
Sigma-Aldrich W255611 γ-Hexalactone natural,97%,FG 695-06-7 500g $2490 2024-03-01 Buy
Sigma-Aldrich W255602 γ-Hexalactone ≥98%,FCC,FG 695-06-7 1kg $200 2024-03-01 Buy
Sigma-Aldrich W255602 γ-Hexalactone ≥98%,FCC,FG 695-06-7 10Kg $1520 2024-03-01 Buy
Sigma-Aldrich 68554 γ-Hexalactone analytical standard 695-06-7 1ml $101 2024-03-01 Buy
Product number Packaging Price Buy
W255611 100g $702 Buy
W255611 500g $2490 Buy
W255602 1kg $200 Buy
W255602 10Kg $1520 Buy
68554 1ml $101 Buy

4-Hexanolide Chemical Properties,Uses,Production

Aroma

Warm, powerfully herbaceous, sweet "Tobacco-like", coumannic type odor. Sweet, powerful, warm-herbaceous, Coumarin-Caramel taste.

Description

gamma-Hexalactone has a warm, powerful, herbaceous, sweet odor and a sweet, coumarin-caramel taste. May be prepared by reduction of sorbic acid using Zn, Sn, or SnCl2 and concentrated HCL in acetic acid solution at 85°C; from ethylene oxide and sodio-malonic ester; also from propyl alcohol and methylacrylate in the presence of di-tert-butyl peroxide.

Chemical Properties

γ-Hexalactone has a sweet, herbaceous, warm, powerful, odor, with a sweet, coumarin-caramel taste. This compound is also described to have odor as sweet, creamy, lactonic, tobacco and coumarin-like with green coconut nuances.

Chemical Properties

4-Hexanolide is colorless liquid. Very slightly soluble in water, soluble in alcohol, Propylene glycol and oils.

Occurrence

Reported found in apple juice, apricot, orange juice, guava, raisin, papaya, peach, pineapple, berries, asparagus, peas, potato, tomato, breads, cheeses, butter, milk, chicken fat, cooked beef, cooked pork, beer, cognac, grape wines, cocoa, tea, filberts, pecans, passion fruit, Japanese plum, beans, mushroom, starfruit, mango, dried fig, prickly pear, licorice, soursop, Cape gooseberry, nectarines, quince, pawpaw and other sources.

Uses

γ-Hexalactone may be used as an analytical standard for the determination of the analyte in wine, fruits, biological samples, meat products, and e-cigarette refill solutions by various chromatography techniques.

Uses

4-Hexanolide was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator.

Uses

γ-Caprolactone was used as curing agent for diglycidyl ether of bisphenol A with ytterbium triflate as an initiator.

Definition

4-Hexanolide is a gamma-lactone that is oxolan-2-one substituted by an ethyl group at position 5.

Application

4-Hexanolide finds some use in perfume compositions as a modifier for Coumarin, in Lavender and Fougere perfumes, and in many other types where Oakmoss is used as a sweetener for mossy notes. This material is more widely used in flavors, where its power and creamy sweetness is utilized for imitation Butter, Honey, Vanilla, Caramel and in fruit complexes and Tobacco flavorings.
The concentration used may vary from 0,1 ppm to 20 ppm in most of the common finished products, except in ice cream where it may be as high as 60 to 90 ppm. It performs very well with Vanillin as a synergist for the Vanilla and Cream-like flavor, an effect previously supplied by Coumarin.

Preparation

By reduction of sorbic acid using Zn, Sn or SnCl2 and concentrated HCl in acetic acid solution at 85°C; from ethylene oxide and sodio-malonic ester; also from propyl alcohol and methylacrylate in the presence of di-tert-butyl peroxide

Aroma threshold values

Detection: 1.6 ppm

Taste threshold values

Taste characteristics at 75 ppm: sweet, creamy, vanilla-like with green lactonic powdery nuances

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 2111, 1987 DOI: 10.1016/S0040-4039(00)96056-8

General Description

γ-Hexalactone is a volatile flavoring compound largely present in food and beverage products, fruits, vegetables, etc.

Biochem/physiol Actions

Taste at 5-10ppm

4-Hexanolide Preparation Products And Raw materials

Global( 294)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Xiangduo Industry Co., Ltd.
+86-15981848961 +86-15981848961 sales@xiangduochem.com China 497 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5873 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5866 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 2990 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20293 58
Shandong Juchuang Chemical Co., LTD
+undefined15030412209 admin@juchuangchem.com China 387 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
JINING XINHE CHEMICAL CO., LTD
+8615318402391 sales@xinhepharma.com China 808 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29888 58

View Lastest Price from 4-Hexanolide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hexanolide pictures 2024-08-21 4-Hexanolide
695-06-7
US $100.00-50.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
γ -Hexalactone pictures 2024-08-15 γ -Hexalactone
695-06-7
US $1.00 / kg 1kg 99% 20tons Hebei Yanxi Chemical Co., Ltd.
4-Hexanolide pictures 2024-07-18 4-Hexanolide
695-06-7
US $0.00-0.00 / kg 1kg 99% 10ton JINING XINHE CHEMICAL CO., LTD
  • 4-Hexanolide pictures
  • 4-Hexanolide
    695-06-7
  • US $100.00-50.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co,.LTD
  • 4-Hexanolide pictures
  • 4-Hexanolide
    695-06-7
  • US $0.00-0.00 / kg
  • 99%
  • JINING XINHE CHEMICAL CO., LTD
4-HYDROXYHEXANOIC ACID G-LACTONE 4-hexanolide 4-Ethyl-4-hydroxybutanoic acid lactone GAMMA-HEXANOLACTONE gamma-Ethylbutyrolactone gamma-Ethyl-n-butyrolactone hexa-4-olide Hexanoic acid, 4-hydroxy-, gamma-lactone Hexanoic acid, 4-hydroxy-, lactone Tonkalide Toukalide GAMMA-HEXALACTONE 98+% FCC Gamma-Caprolac gamma-Hexanolactone,98% 4-hexanolide,γ-ethyl-γ-butyrolactone;γ-caproalctone,γ-hexalactone γ-hexanolactone 5-ethyloxolan-2-one GAMMA-CAPROLAC1000KGE gamma-Hexalactone~gamma-Hexanolactone r-Hexyl Lactone GAMMA-HEXANOICLACTONE HEXALACTON GAMMA Hexan-4-olid γ-Caprolactone, γ-Ethyl-γ-butyrolactone 5-Ethyl-4,5-dihydrofuran-2(3H)-one ^y-Hexanolactone, 98% GAMMA-HEXYL LACTONE GAMMA-ETHYL-GAMMA-BUTYROLACTONE 4-Ethyl-4-butanolide 4-ethylbutanolide (gamma-hexalactone) 4-Hydroxyhexanoic acid lactone 4-hydroxyhexanoicacidlactone G-CAPROLACTONE FOR SYNTHESIS 100 ML γ-Hexanolactone gamma-Caprolactone 98% gamma-Caprolactone Vetec(TM) reagent grade, 98% G-CAPROLACTONE G-HEXALACTONE HEXALACTONE, GAMMA- HEXANOLACTONE, GAMMA- Hexanolide-1,4 Ethyl butyrolactone 5-ethyldihydro-2(3h)-furanon 5-ethyl-dihydro-furan-2-one 5-Ethyltetrahydro-2-furanone γ-Hexanolactone High quality Gamma Hexalactone CAS 695-06-7 γ-Hexalactone,Tonkalide 4-Hexanolide USP/EP/BP γ-Hexanolactone> GAMMA-HEXALACTONE Dihydro-5-ethyl-2(3H)-furanone g-Hexanolactone 2(3H)-Furanone, 5-ethyldihydro- hexan-4-olide GAMMA-CAPROLACTONE FEMA 2556 5-Ethyldihydro-2(3H)-furanone