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4-Aminobenzotrifluoride

4-Aminobenzotrifluoride structure

CAS No.: 455-14-1

Chemical Name:: 4-Aminobenzotrifluoride

Synonyms: 4-(TRIFLUOROMETHYL)ANILINE;aminobenzotrifluoride;-trifluoromethylaniline;4-(Trifluoromethyl)benzenamine;TIMTEC-BB SBB003956;TRIFLUOROMETHYLANILINE;4-aminobenzotrifluride;4-AMINOBENZOTRIFLUORIDE;P-AMINOBENZOTRIFLUORIDE;4-aminotrifluorotoluene

CBNumber:: CB2395593

Molecular Formula:: C7H6F3N

Molecular Weight:: 161.12

MDL Number:: MFCD00064396

MOL File:: 455-14-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:21

Product description	Number	Pack Size	Price
4-(Trifluoromethyl)aniline 99%	224936	1g	$84.3
Leflunomide impurity A European Pharmacopoeia (EP) Reference Standard	Y0000487	30 mg	$244
Leflunomide Related Compound A United States Pharmacopeia (USP) Reference Standard	1357045	100mg	$1390
4-Aminobenzotrifluoride >98.0%(GC)(T)	A0662	25mL	$41
4-Aminobenzotrifluoride >98.0%(GC)(T)	A0662	100mL	$142
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4-Aminobenzotrifluoride Properties

Melting point	3-8 °C
Boiling point	83 °C12 mm Hg(lit.)
Density	1.283 g/mL at 25 °C(lit.)
refractive index	n20/D 1.483(lit.)
Flash point	188 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Liquid
pka	2.45(at 25℃)
color	Clear colorless to yellow
Specific Gravity	1.283
Water Solubility	<0.1 g/100 mL
Sensitive	Air Sensitive
BRN	1564853
InChI	1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2
InChIKey	ODGIMMLDVSWADK-UHFFFAOYSA-N
SMILES	Nc1ccc(cc1)C(F)(F)F
LogP	1.95 at 20℃
CAS DataBase Reference	455-14-1(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	RQJ623MB8G
NIST Chemistry Reference	Benzenamine, 4-(trifluoromethyl)-(455-14-1)
EPA Substance Registry System	4-(Trifluoromethyl)aniline (455-14-1)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS06,GHS09

Signal word

Danger

Hazard statements

H301-H318-H410

Precautionary statements

P264-P270-P273-P280-P301+P310-P305+P351+P338

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

T,N,Xi,Xn

Risk Statements

25-36-50/53-36/37/38-33-20/21/22

Safety Statements

26-45-60-61-36/37/39-36

RIDADR

UN 2810 6.1/PG 3

WGK Germany

RTECS

XU9260000

Hazard Note

Toxic/Irritant

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

III

HS Code

29214300

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
2		0

4-Aminobenzotrifluoride price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	224936	4-(Trifluoromethyl)aniline 99%	455-14-1	1g	$84.3	2026-04-30	Buy
Sigma-Aldrich	Y0000487	Leflunomide impurity A European Pharmacopoeia (EP) Reference Standard	455-14-1	30 mg	$244	2026-04-30	Buy
Sigma-Aldrich	1357045	Leflunomide Related Compound A United States Pharmacopeia (USP) Reference Standard	455-14-1	100mg	$1390	2026-04-30	Buy
TCI Chemical	A0662	4-Aminobenzotrifluoride >98.0%(GC)(T)	455-14-1	25mL	$41	2026-04-30	Buy
TCI Chemical	A0662	4-Aminobenzotrifluoride >98.0%(GC)(T)	455-14-1	100mL	$142	2026-04-30	Buy

Product number	Packaging	Price	Buy
224936	1g	$84.3	Buy
Y0000487	30 mg	$244	Buy
1357045	100mg	$1390	Buy
A0662	25mL	$41	Buy
A0662	100mL	$142	Buy

4-Aminobenzotrifluoride Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow liquid

Uses

4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.

Uses

4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.

Definition

ChEBI: A substituted aniline that is a benzene ring substituted with an amino group at position 1 and a trifluoromethyl group at position 4.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 2873, 1989 DOI: 10.1021/jo00273a020

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

4-Aminobenzotrifluoride Preparation Products And Raw materials

Raw materials

nitrotoluene SODIUM HYPOBROMITE 4-Chlorobenzaldehyde Sodium bromide Phenyl isocyanate

Stannous chloride 4-Nitrotoluene Benzotrichloride PHOSGENE FORMANILIDE

Hydrogen fluoride p-Toluidine 4-Chlorobenzotrifluoride 1-TrifluoroMethyl-1,2-benziodoxol-3(1H)-one 2-Aminobenzotrifluoride

6-Ethyl-o-toluidine

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Preparation Products

2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE Leflunomide 4-TRIFLUOROMETHYL-N-METHYLANILINE 97 ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 4-Amino-3,5-dichlorobenzotrifluoride

ETHYL 4-CHLORO-6-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE 2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE 1,4-Bis(trifluoromethyl)-benzene TRANS-4-(TRIFLUOROMETHYL)CYCLOHEXANAMINE

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4-Aminobenzotrifluoride Suppliers

Global( 647)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13843	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Hefei TNJ Chemical Industry Co.,Ltd.	55

View Lastest Price from 4-Aminobenzotrifluoride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	4-Aminobenzotrifluoride 455-14-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2026-01-04	4-Aminobenzotrifluoride 455-14-1	US $0.00-0.00 / kg	0.10000000149011612kg	99.0%min	2000kg	Hangzhou ICH Biofarm Co., Ltd
2025-12-01	4-Aminobenzotrifluoride 455-14-1	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

4-Aminobenzotrifluoride
455-14-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Aminobenzotrifluoride
455-14-1
US $0.00-0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

4-Aminobenzotrifluoride
455-14-1
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

4-Aminobenzotrifluoride Spectrum

4-Aminobenzotrifluoride(455-14-1)MS 4-Aminobenzotrifluoride(455-14-1)¹HNMR 4-Aminobenzotrifluoride(455-14-1)IR1 4-Aminobenzotrifluoride(455-14-1)IR2 4-Aminobenzotrifluoride(455-14-1)Raman

455-14-1(4-Aminobenzotrifluoride)Related Search:

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TIMTEC-BB SBB003956 P-(TRIFLUOROMETHYL)ANILINE P-AMINOBENZOTRIFLUORIDE 1-AMINO-4-(TRIFLUOROMETHYL)BENZENE 4-AMINOBENZOTRIFLUORIDE 4-AMINO-A,A,A-TRIFLUOROTOLUENE A,A,A-TRIFLUORO-P-TOLUIDINE ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUIDINE 4-(trifluoromethyl)-benzenamin 4-Amino-alpha,alpha,alpha-benzotrifluoride 4-Aminobenzotrifluororide 4-aminotrifluorotoluene alpha,alpha,alpha-trifluoro-p-toluidin Aniline, p-(trifluoromethyl)- p-Amino-alpha,alpha,alpha-trifluorotoluene p-Toluidine, alpha,alpha,alpha-trifluoro- 4-(Trifluoromethyl)aniline,α,α,α-Trifluoro-p-toluidine, 4-Aminobenzotrifluoride 4-(Trifluoromethyl)aniline, 97+% 4-Aminobenzotrifluoride ,99% p-Amino-α,α,α-trifluorotoluene 4/p-Trifluoromethylphenol Leflunomide Related Compound A (100 mg) (4-(trifluoromethyl)aniline) 4-AMinobenzotrifluoride, 99% 10ML LeflunoMide EP IMpurity A 4-(TrifluoroMethyl)aniline 99% The aMino trifluoro toluene 4-(trifluoromethyl)aniline [KSM] 4-(Trifluoromethyl)aniline (Leflunomide Related Compound A) 4-Aminobenzotrifluoride for synthesis LeflunoMide Related CoMpound A 4-TRIFLUOROMETHYLANILINE 98+% 4-(Trifluoromethyl)phenylamine 4-AMINOBENZOTRIFLUORIDE 98.5% 4-AMINOBENZOTRIFLUORIDE 99.0% trifluoromehylphenylanilide 4-Aminobenzotrifluoride;4-(Trifluoromethyl)aniline TRIFLUOROMETHYLANILINE Benzenamine, 4-(trifluoromethyl)- 4-AMINOBENZOTRIFLOURIDE 4-Aminobenzotrifluoride 97% 4-Aminobenzotrifluoride97% 4/p-Aminobenzotrifluoride 4-(Trifluoromethyl)aniline, alpha,alpha,alpha-Trifluoro-p-toluidine 4-Aminobenzotrifluoride, 98+% α,α,α-Trifluoro-p-toluidine, 4-Aminobenzotrifluoride Leflunomide Impurit I:4-Aminobenzotrifluoride Leflunomide Impurity 1(Leflunomide EP Impurity A) Leflunomide impurity A CRS Leflunomide impurityⅠ[4-(trifluoromethyl)aniline] 4-Aminobenzotrifluoride> 4-aminobenzotrifluride Leflunomide EP Impurity A/ Leflunomide Related Compound A 4-(Trifluoromethyl)aniline Hydroiodide Leflunomide impurities1340 Leflunomide Related Compound A (4-(trifluoromethyl)aniline) (1357045) Leflunomide impurityⅠ [4-(trifluoromethyl)aniline 4-(TRIFLUOROMETHYL)ANILINE 4-(Trifluoromethyl)benzenamine