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ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate structure

CAS No.: 330785-99-4

Chemical Name:: ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate

Synonyms: RSYY（Lifitegrast)-7;Avanafil Impurity V;2-hydroxy-4-(3-chloro-4-methoxybenzylamino)-5-ethoxycarbonylpyrimidine;ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate;Ethyl 6-((3-chloro-4-methoxybenzyl)amino)-2-oxo-1,2-dihydropyrimidine-5-carboxylate;5-Pyrimidinecarboxylic acid, 6-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1,2-dihydro-2-oxo-, ethyl ester

CBNumber:: CB23975334

Molecular Formula:: C15H16ClN3O4

Molecular Weight:: 337.76

MDL Number:: MFCD31922574

MOL File:: 330785-99-4.mol

Last updated:2023-07-01 08:28:08

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ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate Properties

Density	1.37±0.1 g/cm3(Predicted)
pka	7.73±0.10(Predicted)

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate Chemical Properties,Uses,Production

Uses

Ethyl 4-((3-Chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate is an Avanafil related substance. Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate synthesis

Synthesis of ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate from 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylsulfinylpyriMidine

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	4996	50
Taizhou Tongxin Bio-Tech Co., Ltd	0523-18601685-898 18652728585	sales@allyrise.com	China	2740	60
ChemStrong Scientific Co.,Ltd	0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shenzhen SUNGENING Bio-Medical Co., Ltd.	0755-28967200 13631290199	wxf@sungening.com	China	9506	60
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-69900633 18340090523	changyuan20@163.com	China	1715	58
Cato Research Chemicals Inc.	020-81215950 4000-868-328	customer@uwalab.com	United States	10413	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-400-8210725 4008210725	malulu@leyan.com	China	55023	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	0755-0755-0755-83725350 13380397412	3001280422@qq.com	China	9934	58

Supplier	Advantage
Career Henan Chemica Co	58
China National Standard Pharmaceutical Corporation Limited	58
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
Taizhou Tongxin Bio-Tech Co., Ltd	60
ChemStrong Scientific Co.,Ltd	56
Shenzhen SUNGENING Bio-Medical Co., Ltd.	60
Jinan Ruisi Pharmaceutical Technology Co., LTD	58
Cato Research Chemicals Inc.	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	58

ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-hydroxypyrimidine-5-carboxylate 2-hydroxy-4-(3-chloro-4-methoxybenzylamino)-5-ethoxycarbonylpyrimidine Avanafil Impurity V RSYY（Lifitegrast)-7 Ethyl 6-((3-chloro-4-methoxybenzyl)amino)-2-oxo-1,2-dihydropyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 6-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1,2-dihydro-2-oxo-, ethyl ester 330785-99-4