ChemicalBook >> CAS DataBase List >>1-Methylindole-2-carboxylic acid

1-Methylindole-2-carboxylic acid

CAS No.
16136-58-6
Chemical Name:
1-Methylindole-2-carboxylic acid
Synonyms
1-Me-ICA;NSC 68357;AKOS JY2082906;RARECHEM AL BE 0864;2-Carboxy-1-methyl-1H-indole;1-methyl-2-indolecarboxylicacid;1-METHYLINDOLE-2-CARBOXYLIC ACID;N-METHYL-2-INDOLECARBOXYLIC ACID;1-Methyl-2-indolecarboxylic acid;N-Methylindole-2-carboxylic acid
CBNumber:
CB2398286
Molecular Formula:
C10H9NO2
Molecular Weight:
175.18
MDL Number:
MFCD00005801
MOL File:
16136-58-6.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:37

1-Methylindole-2-carboxylic acid Properties

Melting point 212-213 °C (dec.) (lit.)
Boiling point 389.0±15.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Crystalline Powder
pka 4.19±0.30(Predicted)
color Beige
CAS DataBase Reference 16136-58-6(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference 1-Methylindole-2-carboxylic acid(16136-58-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
RTECS  NL6012400
HazardClass  IRRITANT
HS Code  29339980
NFPA 704
0
2 0

1-Methylindole-2-carboxylic acid price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 134155 1-Methylindole-2-carboxylic acid 98% 16136-58-6 1g $82.5 2023-06-20 Buy
Sigma-Aldrich 134155 1-Methylindole-2-carboxylic acid 98% 16136-58-6 5g $250 2023-06-20 Buy
TCI Chemical M1519 1-Methylindole-2-carboxylic Acid >98.0%(GC)(T) 16136-58-6 1g $49 2024-03-01 Buy
TCI Chemical M1519 1-Methylindole-2-carboxylic Acid >98.0%(GC)(T) 16136-58-6 5g $141 2024-03-01 Buy
TRC M313615 1-Methylindole-2-carboxylic acid 16136-58-6 1g $75 2021-12-16 Buy
Product number Packaging Price Buy
134155 1g $82.5 Buy
134155 5g $250 Buy
M1519 1g $49 Buy
M1519 5g $141 Buy
M313615 1g $75 Buy

1-Methylindole-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

Beige crystalline powder

Uses

  • Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
  • Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
  • Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
  • Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
  • Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
  • Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors

Uses

• ;Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1• ;Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2• ;Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3• ;Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4• ;Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications ag

General Description

1-Methylindole-2-carboxylic acid reacts with thionyl chloride to yield sulfinyl chlorides.

1-Methylindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 186)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58

View Lastest Price from 1-Methylindole-2-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Methylindole-2-carboxylic acid pictures 2020-01-03 1-Methylindole-2-carboxylic acid
16136-58-6
US $6.60 / KG 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co
RARECHEM AL BE 0864 N-METHYL-2-INDOLECARBOXYLIC ACID 1H-Indole-2-carboxylic acid, 1-methyl- 1-methyl-1h-indole-2-carboxylicaci 1-Methyl-2-indolecarboxylic acid 1-methyl-2-indolecarboxylicacid Indole-2-carboxylic acid, 1-methyl- AKOS JY2082906 1-METHYLINDOLE-2-CARBOXYLIC ACID 1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 1-Me-ICA 1-Methylindole-2-CarboxylicAcid97% 1-Methylindole-2-carboxylic acid, 1-Methyl-1H-indole-2-carboxylic acid, 99% 1-Methylindole-2-carboxylic acid ,98% N-Methylindole-2-carboxylic acid NSC 68357 2-Carboxy-1-methyl-1H-indole 1-Methylindole-2-carboxylicAcid> 16136-58-6 Building Blocks Heterocyclic Building Blocks Indoles Building Blocks C10 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Indoles Indoles and derivatives Organic acids