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Ascomycin

Ascomycin
Ascomycin structure
CAS No.
104987-12-4
Chemical Name:
Ascomycin
Synonyms
AAG;CBR02;FK-520;FR 520;C058028;CS-1818;L 683590;FR-900520;Ascomycin;IMMUNOMYCIN
CBNumber:
CB2406330
Molecular Formula:
C43 H69 N O12
Formula Weight:
792.01
MOL File:
104987-12-4.mol

Ascomycin Properties

Melting point:
153-157°C
Boiling point:
868℃
Density 
1.19±0.1 g/cm3(Predicted)
Flash point:
>110°(230°F)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
9.97±0.70(Predicted)
Water Solubility 
Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water
InChIKey
ZDQSOHOQTUFQEM-AMASXYNMSA-N
CAS DataBase Reference
104987-12-4
FDA UNII
AUF4U5NSJK
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H332-H319-H302-H312-H332
Precautionary statements  P210-P305+P351+P338-P261-P280h-P301+P312a-P304+P340-P321-P501a
Hazard Codes  Xn,F
Risk Statements  20/21/22-36-11
Safety Statements  36/37-16
RIDADR  UN 1648 3 / PGII
WGK Germany  3
RTECS  KD4185000
10
HS Code  29419090

Ascomycin price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A-094 Ascomycin solution 1.0mg/mL in acetonitrile, ampule of 1mL, certified reference material 104987-12-4 094-1ml $220 2020-08-18 Buy
Sigma-Aldrich A-094 Ascomycin solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 104987-12-4 1 mL $227 2021-03-22 Buy
Sigma-Aldrich A3835 Ascomycin from Streptomyces hygroscopicus var. ascomyceticus 104987-12-4 1mg $229 2021-03-22 Buy
Alfa Aesar J66751 Ascomycin, 95% 104987-12-4 100mg $467 2020-06-24 Buy
Alfa Aesar J66751 Ascomycin, 95% 104987-12-4 25mg $152 2020-06-24 Buy

Ascomycin Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases

Uses

Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1988. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant.

Uses

Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations.

Definition

ChEBI: A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties.

Ascomycin Preparation Products And Raw materials

Raw materials

Preparation Products


Ascomycin Suppliers

Global( 162)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
NANJING SUNSHINE BIOTECH CO.,LTD
+86-25-86189929
+86-25-86189616 brian@sunshine-bio.com CHINA 128 58
Fuxin Pharmaceutical
021-50872116
contact@fuxinpharm.com CHINA 9519 58
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26734 60
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14344 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19753 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29865 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
ENBRIDGE PHARMTECH CO., LTD.
13812269233
0510-83591909 sales@enbridgepharm.com CHINA 216 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
86-021-61999440
contact@trustwe.com CHINA 9885 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58

View Lastest Price from Ascomycin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-13 Ascomycin
104987-12-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10 Ascomycin
104987-12-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2019-12-26 Ascomycin
104987-12-4
US $6.60 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

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