DENDROTOXIN-K

DENDROTOXIN-K structure

CAS No.

Chemical Name:: DENDROTOXIN-K

Synonyms: DENDROTOXIN-K

CBNumber:: CB2411934

Molecular Formula:

Molecular Weight:: 0

MDL Number:: MFCD01866187

MOL File:: Mol file

Last updated:2023-04-23 13:52:06

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DENDROTOXIN-K Properties

storage temp.	−20°C
form	lyophilized powder

SAFETY

Risk and Safety Statements

RIDADR	UN 3462 6.1/PG 3
WGK Germany	3

DENDROTOXIN-K price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D4813	Dendrotoxin-K ≥98% (HPLC), lyophilized powder		1VIAL	$384	2023-06-20	Buy

Product number	Packaging	Price	Buy
D4813	1VIAL	$384	Buy

DENDROTOXIN-K Chemical Properties,Uses,Production

Uses

Dendrotoxin-K is suitable for use as a potassium voltage-gated channel subfamily A member 1 (Kv1.1) channel blocker in axon and human embryonic kidney (HEK293) cells. It has also been used as a selective blocker of Kv channels in mice.

Biochem/physiol Actions

Dendrotoxin-K (DTXk) is isolated from mamba snake Dendroaspis polylepis and interacts with the β-turn region in the N-terminal sequence of the potassium channel. It inhibits tumor progression in gefitinib-resistant non-small cell lung cancer cells. DTXk induces neuronal damage in the hippocampus via N-methyl-d-aspartate (NMDA) and non-NMDA receptors.

DENDROTOXIN-K Preparation Products And Raw materials

Raw materials

Preparation Products

DENDROTOXIN-K Suppliers

Global( 10)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

Supplier	Advantage
Sigma-Aldrich	80

(DENDROTOXIN-K)Related Search:

DENDROTOXIN

DENDROTOXIN-K Voltage-gated Ion Channels Ion Channels Potassium Channel Modulators Monovalent Ion Channels BioChemical Cell Signaling and Neuroscience Cell Biology Monovalent Ion Channels Potassium Channel Modulators Voltage-gated Ion Channels