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Rebeprazole sodium

Anti-ulcer drug Uses
Rebeprazole sodium
Rebeprazole sodium
CAS No.
117976-90-6
Chemical Name:
Rebeprazole sodium
Synonyms
Parie;PARIET;Pariprazole;RABEPRAZOL SODIUM;RABEPRAZOLE SODIUM;rebeprazole sodium;SODIUM RABEPRAZOLE;Rabeprazole SoduiM;Dexrabeprazole SodiuM;Rabeprazole SodiuM USP
CBNumber:
CB2420819
Molecular Formula:
C18H20N3NaO3S
Formula Weight:
381.42
MOL File:
117976-90-6.mol

Rebeprazole sodium Properties

Melting point:
140-141°C dec.
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
H2O: soluble10mg/mL (clear solution)
form 
powder
color 
white to beige
Merck 
14,8089
InChIKey
KRCQSTCYZUOBHN-UHFFFAOYSA-N

SAFETY

WGK Germany  3

Rebeprazole sodium price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1525 Rabeprazole Sodium Pharmaceutical Secondary Standard; Certified Reference Material 117976-90-6 1g $97.3 2018-11-20 Buy
Sigma-Aldrich 1598019 Rabeprazole sodium United States Pharmacopeia (USP) Reference Standard 117976-90-6 200mg $583.1 2018-11-20 Buy
TCI Chemical R0115 Rabeprazole Sodium Salt >98.0%(HPLC) 117976-90-6 100mg $120 2018-11-22 Buy
TCI Chemical R0115 Rabeprazole Sodium Salt >98.0%(HPLC) 117976-90-6 1g $500 2018-11-22 Buy
Cayman Chemical 14939 Rabeprazole (sodium salt) ≥98% 117976-90-6 5mg $25 2018-11-13 Buy

Rebeprazole sodium Chemical Properties,Uses,Production

Anti-ulcer drug

Rabeprazole sodium is a anti-ulcer disease drug belonging to proton pump inhibitor and is the sodium salt form of Rabeprazole. The Japanese company Eisai had successfully developed it for the first time with the trade name being “Bolite”. The function of the proton pump inhibitors is reducing the gastric acid secretion so that the lesion site can be stable in order to achieving the effect of curing gastric and duodenal ulcers and stomach-esophageal reflux disease. Clinically it is majorly used for the treatment of acid-related diseases such as stomach and duodenal ulcers, peptic ulcer, gastroesophageal reflux disease and zollinger-ellison syndrome. Rabeprazole is a kind of benzimidazole-substituted compounds. It inhibits the secretion of gastric acid through forming bond with the cytoplasmic proton pump in the gastric cavity wall. This product can specifically inhibit the effect of the adenosine triphosphatase that is the key enzyme during the production of stomach acid. It has inhibitory effect on both basal gastric acid and the gastric acid secretion caused by the stimulation.
Rabeprazole is white-yellowish-white powder with no odor and a molecular weight being 381.43. This product is highly soluble in water or methanol, also soluble in ethanol or ethyl acetate but almost insoluble in ether or ethane. This product does not exhibit optical activity, has hygroscopic effect. Its melting point is 225 ℃ and its partition coefficient at water/octane system of pH 7.0 is about 214. This product is light yellow film-coated tablets (enteric-coated tablets).
Adverse reactions and precautions: gastric cancer should be excluded after use of the drug. Adverse reactions include allergic reactions, palpitations, constipation, diarrhea, headache, edema, leukopenia, AST, ALT, total bilirubin and proteinuria. The combination of Rabeprazole sodium and digoxin can cause increased digoxin concentration. It can’t be taken simultaneously with antacids. Patients of history of drug allergy, cirrhosis, the elderly, pregnant and lactating women, children should take with caution.
The above information is edited by the chemicalbook of Dai Xiongfeng.

Uses

It belongs to national second-class drug that can be used for the treatment of gastric ulcer. It can be used for the treatment of peptic ulcer, gastroesophageal reflux disease, zollinger-ellison syndrome and other diseases.

Chemical Properties

White Crystalline Solid

Uses

anthelminthic, antiseptic, expectorant

Uses

antibacterial and antifungal agent effective against gram-positive and gram-negative bacteria, yeast and fungi

Uses

A partially reversible gastric proton pump inhibitor

brand name

Aciphex (Eisai Medical Research) .

Rebeprazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products


Rebeprazole sodium Suppliers

Global( 229)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 663 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
QUALITY CONTROL CHEMICALS INC.
13606120588
orders@qcchemical.com CHINA 8430 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 305 58
Jinan Jianfeng Chemical Co., Ltd
15562555968
info@pharmachemm.com CHINA 617 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19990 58

View Lastest Price from Rebeprazole sodium manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-03-12 Rebeprazole sodium 117976-90-6
117976-90-6
US $30.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.
2018-12-15 Rebeprazole sodium
117976-90-6
US $1.00 / kg 1kg 99% Customized career henan chemical co

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