EPA
- CAS No.
- 25378-27-2
- Chemical Name:
- EPA
- Synonyms
- EPA;CLGI;ICOSAPENT;C20:5 OMEGA-3;TIMNODONIC ACID;Icosapent ethyl;C20:5N-3FATTYACID;EICOSAPENTAENOATE;EICOSAPENTANOICACID;eicosapentenoicacid
- CBNumber:
- CB2426442
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MDL Number:
- MFCD00065716
- MOL File:
- 25378-27-2.mol
| Melting point | −54-−53 °C(lit.) |
|---|---|
| Density | 0.943 g/mL at 25 °C(lit.) |
| refractive index |
n |
| storage temp. | −20°C |
| form | liquid |
| EWG's Food Scores | 1 |
| FDA UNII | AAN7QOV9EA |
| NCI Drug Dictionary | eicosapentaenoic acid |
SAFETY
Risk and Safety Statements
| Hazard Codes | C |
|---|---|
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3265 8/PG 3 |
| WGK Germany | 3 |
| F | 8-10-23 |
| Toxicity | human,TDLo,oral,560mg/kg (560mg/kg),BLOOD: OTHER CHANGES,Lancet. Vol. 2, Pg. 197, 1981. |
EPA price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2501702 | Anti-TIMP1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 25378-27-2 | 100μg | $545 | 2023-01-07 | Buy |
| Cayman Chemical | 90110 | Eicosapentaenoic Acid ≥98% | 25378-27-2 | 50mg | $29 | 2021-12-16 | Buy |
| Cayman Chemical | 90110 | Eicosapentaenoic Acid ≥98% | 25378-27-2 | 100mg | $55 | 2021-12-16 | Buy |
| Cayman Chemical | 90110 | Eicosapentaenoic Acid ≥98% | 25378-27-2 | 250mg | $109 | 2021-12-16 | Buy |
| Cayman Chemical | 90110 | Eicosapentaenoic Acid ≥98% | 25378-27-2 | 500mg | $203 | 2021-12-16 | Buy |
EPA Chemical Properties,Uses,Production
Description
Eicosa pentaenoic acid ( EPA or also icosapentaenoic acid ) is an omega-3 fatty acid. In physiological literature, it is given the name 20:5(n-3). It also has the trivial name timnodonic acid. In chemical structure, EPA is a carboxylic acid with a 20-carbon chain and five cis double bonds; the first double bond is located at the third carbon from the omega end.
EPA is a polyunsaturated fatty acid (PUFA) that acts as a precursor for prostaglandin-3 (which inhibits platelet aggregation), thromboxane-3, and leukotriene-5 groups (all eicosanoids).
Occurrence
It is obtained in the human diet by eating oily fish or fish oil — e.g., cod liver, herring, mackerel, salmon, menhaden and sardine, and various types of edible seaweed. It is also found in human breast milk.
However, fish do not naturally produce EPA, but obtain it from the algae they consume. It is available to humans from some non - animal sources (e.g., commercially, from microalgae). Microalgae are being developed as a commercial source. EPA is not usually found in higher plants, but it has been reported in trace amounts in purslane.
The human body converts alpha-linolenic acid (ALA) to EPA. ALA is itself an essential fatty acid, an appropriate supply of which must be ensured. The efficiency of the conversion of ALA to EPA, however, is much lower than the absorption of EPA from food containing it. Because EPA is also a precursor to docosahexaenoic acid (DHA), ensuring a sufficient level of EPA on a diet containing neither EPA nor DHA is harder both because of the extra metabolic work required to synthesize EPA and because of the use of EPA to metabolize DHA. Medical conditions like diabetes or certain allergies may significantly limit the human body's capacity for metabolization of EPA from ALA.
Uses
eicosapentaenoic acid is also known as ePA. With emollient and skin-conditioning properties, this omega-3 fatty acid helps repair and maintain the skin barrier functions. It is said to improve the structure and function of the skin cell membrane. In addition, it may also have anti-irritant and anti-inflammatory properties.
brand name
Decabid (Lilly).
EPA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Xi'an ZB Biotech Co.,Ltd | +8618591943808 | sales01@xazbbio.com | China | 816 | 58 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18501085097 | sales3.gd@hwrkchemical.com | China | 7583 | 55 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14067 | 55 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2773 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1976 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd. | 13720616393；029-84385017-8003 13720616393 | sales@pioneerbiotech.com | China | 1065 | 56 |
| Wu han Spring Pharmaceutical Technology Co.,Ltd | 027-87689766 13797071802 | sales@sprchem.com | China | 56 | 55 |
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