C8 CERAMIDE
- CAS No.
- 74713-59-0
- Chemical Name:
- C8 CERAMIDE
- Synonyms
- C8 CERAMIDE;CERAMIDE C8;08:0 CERAMIDE;N-Octanoyl-D-erythr;N-OCTANOYLSPHINGOSINE;C8-D-ERYTHRO-CERAMIDE;C8 CERAMINE, D-ERYTHRO;N-Octanoyl-D-erythro-sp;C8 Ceramide (d18:1/8:0);N-OCTANOYL-D-SPHINGOSINE
- CBNumber:
- CB2432038
- Molecular Formula:
- C26H51NO3
- Molecular Weight:
- 425.69
- MDL Number:
- MFCD00236496
- MOL File:
- 74713-59-0.mol
| Melting point | 68-70°C |
|---|---|
| Boiling point | 541.37°C (rough estimate) |
| Density | 0.9974 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | −20°C |
| solubility | DMSO or ethanol: soluble |
| form | waxy solid |
| color | White |
| Stability | Temperature Sensitive |
| CAS DataBase Reference | 74713-59-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29225000 |
C8 CERAMIDE price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J67190 | C8 Ceramide, 98% | 74713-59-0 | 5mg | $89.7 | 2021-12-16 | Buy |
| Alfa Aesar | J67190 | C8 Ceramide, 98% | 74713-59-0 | 25mg | $333 | 2021-12-16 | Buy |
| Cayman Chemical | 62540 | C-8 Ceramide ≥98% | 74713-59-0 | 1mg | $20 | 2024-03-01 | Buy |
| Cayman Chemical | 62540 | C-8 Ceramide ≥98% | 74713-59-0 | 5mg | $69 | 2024-03-01 | Buy |
| Cayman Chemical | 62540 | C-8 Ceramide ≥98% | 74713-59-0 | 10mg | $127 | 2024-03-01 | Buy |
C8 CERAMIDE Chemical Properties,Uses,Production
Description
C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4
Chemical Properties
Off White Powder
Uses
A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis
Uses
C-8 Ceramide is a ceramide analog.
Definition
ChEBI: N-octanoylsphingosine is an N-acylsphingosine in which the ceramide N-acyl group is specified as octanoyl. It is functionally related to an octanoic acid.
References
1) Mathias?et al. (1991) Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha; Proc. Natl. Acad. Sci. USA,?88?109 2) Jarvis?et al. (1993)?Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway; Proc. Natl. Acad. Sci. USA?91?73 3) Upham?et al. (2003),?Differential roles of 2,6 and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis; Cancer Lett.,?191?27 4) Nakajima?et al. (2002),?Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro; J. Neurochem.,?80?697
C8 CERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| Shanghai Renshi Pharmatech Co., LTD | 021-26018649 17721318029 | info@renshipharma.com | China | 109 | 55 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |
View Lastest Price from C8 CERAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-23 | C8 CERAMIDE
74713-59-0
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
-
- C8 CERAMIDE
74713-59-0
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
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