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TAPS

CAS No.
29915-38-6
Chemical Name:
TAPS
Synonyms
TAP;3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID;TAPS;TAPS,99%;TAPS,min;TAPS BIOXTRA;TAPS, ULTROL;Taps, puriss;TAPS ULTRAPURE;TAPS SIGMAULTRA
CBNumber:
CB2433242
Molecular Formula:
C7H17NO6S
Molecular Weight:
243.28
MDL Number:
MFCD00007538
MOL File:
29915-38-6.mol
MSDS File:
SDS
Last updated:2024-03-20 09:36:42

TAPS Properties

Melting point 230-235 °C (dec.)
Density 1.4290 (rough estimate)
refractive index 1.6370 (estimate)
Flash point 110 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: 1 M at 20 °C, clear, colorless
pka 8.55; pKa (37°): 8.1; pKa2 (25°): 8.28
form Solid
color White
Odor Odorless
PH Range 7.7 - 9.1
Water Solubility Soluble
Merck 13,9148
BRN 2452420
Stability Stable. Incompatible with strong oxidizing agents
InChIKey YNLCVAQJIKOXER-UHFFFAOYSA-N
CAS DataBase Reference 29915-38-6(CAS DataBase Reference)
FDA UNII Y5DC3IN066
EPA Substance Registry System 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- (29915-38-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
TSCA  Yes
HazardClass  IRRITANT
HS Code  29221980
NFPA 704
0
0 0

TAPS price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T5130 TAPS ≥99.5% (titration) 29915-38-6 1kg $632 2024-03-01 Buy
Sigma-Aldrich 394675 TAPS, ULTROL 29915-38-6 1kg $638 2024-03-01 Buy
TCI Chemical T0974 N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component for biological research] >98.0%(T) 29915-38-6 25g $31 2024-03-01 Buy
Alfa Aesar A17754 TAPS, 99% 29915-38-6 25g $40.65 2024-03-01 Buy
Alfa Aesar A17754 TAPS, 99% 29915-38-6 100g $97.65 2024-03-01 Buy
Product number Packaging Price Buy
T5130 1kg $632 Buy
394675 1kg $638 Buy
T0974 25g $31 Buy
A17754 25g $40.65 Buy
A17754 100g $97.65 Buy

TAPS Chemical Properties,Uses,Production

Description

TAPS is a zwitterionic buffering agent used in biochemistry and molecular biology. It is part of the Tris family of buffers and is useful for a pH range of 7.7 – 9.1. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers[1]. The solubilities of TAPS in aqueous solution decrease with increasing concentration of the salts (salting-out effect)[2]. TAPS is the preferred culture media buffer used for dinoflagellate experiments, allowing for minimal pH change and maximal growth. It is also often used in capillary electrophoresis to analyze DNA and in planar chromatography to separate dyes. TAPS may form a complex with some common metals so stability constants and concentrations should be taken into account when choosing this buffer. TAPS is capable of inhibiting connexin channels in animal cells.

Chemical Properties

White/clear crystalline powder

Uses

A zwitterionic Good's Buffer

Definition

ChEBI: N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid is an organosulfonic acid.

Application

TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.TAPS

References

[1] Gupta B, et al. Stability Constants for the Equilibrium Models of Iron(III) with Several Biological Buffers in Aqueous Solutions. Journal of Solution Chemistry, 2013; 42: 2296–2309.
[2] Taha M, et al. New Insights into Buffer-Ionic Salt Interactions: Solubilities, Transfer Gibbs Energies, and Transfer Molar Volumes of TAPS and TAPSO from Water to Aqueous Electrolyte Solutions. Journal of Solution Chemistry, 2010; 39: 1665–1680.

1120-71-4
77-86-1
29915-38-6
Synthesis of TAPS from 1,3-Propane sultone and Tris(hydroxymethyl)aminomethane

TAPS Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 389)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Xindesheng Material Technology Co., Ltd.
+8618971041571 vickyzhao@whdschem.com China 174 58
Suzhou Genemill Biotechnology Co.,Ltd
+86-0512-65917170; +8615862502491 aimeegao@genemill.com China 39 58
Suzhou BEC Biological Technology Co., Ltd.
+undefined13771885869 all@bek.com.cn China 62 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15933 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60

View Lastest Price from TAPS manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-[Tris(hydroxymethyl)methylamino]-1-propanesulfonic acid pictures 2024-04-28 3-[Tris(hydroxymethyl)methylamino]-1-propanesulfonic acid
29915-38-6
US $5.00 / KG 1KG 99% 200mt/year Jinan Finer Chemical Co., Ltd
TAPS pictures 2024-04-12 TAPS
29915-38-6
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
TAPS pictures 2024-02-20 TAPS
29915-38-6
US $0.00 / kg 1kg 0.995 200tons Suzhou Genemill Biotechnology Co.,Ltd
  • TAPS pictures
  • TAPS
    29915-38-6
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • TAPS pictures
  • TAPS
    29915-38-6
  • US $0.00 / kg
  • 0.995
  • Suzhou Genemill Biotechnology Co.,Ltd
3-[[TRIS(HYDROXYMETHYL)METHYL]AMINO]PROPANESULFONIC ACID 3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]-PROPANESULPHONIC ACID 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid [2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]AMINO)-1-PROPANESULFONIC ACID TAPS N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANESULFONIC ACID N-TRIS(HYDROXYMETHYL)METHYL-3-AMINOPROPANE-SULPHONIC ACID TAPS, for biochemistry, 99+% TAPS,BIOLOGICALBUFFER TRIS-PROPANESULFONICACID N-[Tris(hydroxymethyl)methyl]-3-amino propanesulfonic acid (TAPS) 3-[TRIS(HYDROXYMETHYL)METHYLAMINO]-1-PROPANESULFONIC ACID TAPS TAPS ULTRAPURE N-[tris(hydroxymethyl)methyl]-3-amionpropanesulfonicacid N-TRIS(HYDROXYMETHYL) METHYL-3-AMINOPROPANE SULPHONIC ACID extrapure N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid 3-(tris(Hydroxymethyl)methylamino)propane-1-sulfonic acid 3-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid Taps, 99+%, for biochemistry TAPS, for biochemistry 3-[2-Hydroxy-1,1-bis(hydroxymethyl)ethylamino]propane-1-sulfonic acid N-(3-Sulfopropyl)tris(hydroxymethyl)methaneamine 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic acid >99% N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component for biological research] TAPS,99% N-Tris(Hydroxymethy)methyl-3-aminopropanesulfonic acid 3-[Tris(hydroxymethyl)methylamino]-1-propan N-(tris(hydroxymethy N-Tris (hydroxyMethy) Methyl-3-aMinopropanesulfonic acid(TAPS) Tris(hydroxymethyl)methyl-3-aminopropane sulfonic acid 1-Propanesulfonic acid, 3-2-hydroxy-1,1-bis(hydroxymethyl)ethylamino- 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonicaci tris(hydroxymethyl)methylaminopropansulfonic tris(hydroxymethyl)methylaminopropansulfonicacid tris-Hydroxymethyl methylamino-3-propane sulfonic acid TAPS FREE ACID, BIOTECHNOLOGY PERFORMANC E CERTIFIED N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINO-PR OPANESULFONIC ACI TAPS SIGMAULTRA TAPS, MINIMUM 99.5% (TITRATION) TAPS FREE ACID CRYSTALLINE Taps3-[Tris(Hydroxymethyl)Methylamino]-1-PropanesulfonicAcid Taps(N-Tris[Hydroxymethyl]Methyl-3-AminoPropanesulfonicAcid) 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic acid (TAPS) TAPS (N-Tris[hydroxyMethyl]Methyl-3-aMinopropanesulfonic acid),Free Acid 3-[N-Tris-(hydroxyMethyl)MethylaMino]propanesulphonic (TAPS) 3-(tris(hydroxymethyl)methylamino)propane-1-sulphonic acid Vesicle-docking protein N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid TAPS Vetec(TM) reagent grade, 99.5% N-[Tris(hydroxymethyl)metyl]-3-aminopropanesulfonic acid 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic N-[Tris(hydroxymethyl)methyl]-3-aminopranesulfonic acid TAPS BIOXTRA TAPS, BIOPERFORMANCE CERTIFIED, CELL TAPS, ULTROL TAPS, ULTROL Grade - CAS 29915-38-6 - Calbiochem Tris(hydroxymethyl)methylaminopropanesulfonic acid 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]ammonio]-1-propanesulfonate