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3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE structure

CAS No.: 9040-59-9

Chemical Name:: 3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE

Synonyms: PDE 3B;EC 3.1.4.17;PHOSPHODIESTERASE;Phosphodiesterase 3B;(4-Nitrobenzyl)arsonic acid;Phosphodiesterasefrombovinebrain;Phosphodiesterase 3B, Recombinant;3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE;PHOSPHODIESTERASE 3':5'-CYCLIC NUCLEOTIDE;Phosphodiesterase, cyclic 3',5'-nucleotide

CBNumber:: CB2437361

Molecular Formula:

Molecular Weight:: 0

MDL Number:: MFCD00131864

MOL File:: Mol file

Last updated:2023-04-23 13:52:06

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3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Properties

storage temp.	-20°C
form	lyophilized powder
EWG's Food Scores	1

SAFETY

Risk and Safety Statements

WGK Germany	3

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P9529	Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain 15-30?units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)), lyophilized powder	9040-59-9	1unit	$471	2022-05-15	Buy
American Custom Chemicals Corporation	ENZ0000358	3',5'-CYCLIC-NUCLEOTIDE-5'-NUCLEOTIDOHYDROLASE 95.00%	9040-59-9	5MG	$500.81	2021-12-16	Buy

Product number	Packaging	Price	Buy
P9529	1unit	$471	Buy
ENZ0000358	5MG	$500.81	Buy

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Chemical Properties,Uses,Production

Uses

Phosphodiesterase, 3′,5′-cyclic-nucleotide-specific from bovine brain has been used to assay the protein activator, calmodulin and in in vitro adenylate cyclase assay.

Uses

For use in calmodulin (P 0270) assay. Activity is reduced to <50% without calmodulin present.

General Description

Phosphodiesterase (PDE1) exists in two isoforms -PDE1A2 and PDE1B1. The enzyme has a role in the complex interaction between cyclic nucleotides and Ca²⁺ second-messenger systems.

Biochem/physiol Actions

Hydrolyzes the 3′,5′-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5′-monophosphate.

Clinical Use

Phosphodiesterase-3 (PDE3) is an enzyme responsible for degradation of cAMP to AMP in platelets and blood vessels. Selective cAMP PDE3 inhibitors, such as dipyridamole and cilostazol , inhibit the degradation of cAMP, thereby increasing cellular concentration of cAMP and leading to inhibition of platelet aggregation and vasodilation.

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Preparation Products And Raw materials

Raw materials

Preparation Products

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE Suppliers

Global( 21)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Guangzhou Tomums Life Science Co., Ltd.	020-31155029 18902330969	sales@tomums.cn	China	4698	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	17691182729 18161915376	1046@dideu.com	China	10010	58
Shanghai Huzhen Industrial Co., LTD	021-60345367 13916550749	sales@shzbio.com	China	9965	58
Shanghai Yingxin laboratory equipment Co., Ltd	021-021-59178156 15300768757	359382369@qq.com	China	10367	58
Shanghai Guchen Biotechnology Co., LTD	021-34675735 19147740836	1986399151@qq.com	China	9849	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Creative Enzymes	58
Aladdin Scientific	58
Sigma-Aldrich	80
Guangzhou Tomums Life Science Co., Ltd.	58
Energy Chemical	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	58
Shanghai Huzhen Industrial Co., LTD	58
Shanghai Yingxin laboratory equipment Co., Ltd	58
Shanghai Guchen Biotechnology Co., LTD	58

9040-59-9(3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE)Related Search:

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3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE phosphodiesterase 3':5'-cyclic*nucleotide crude C Phosphodiesterase, cyclic 3',5'-nucleotide PHOSPHODIESTERASE 3':5'-CYCLIC*NUCLEOTID E FROM BOVI PHOSPHODIESTERASE 3':5'-CYCLIC*NUCLEOTID E CRUDE COM Phosphodiesterasefrombovinebrain 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase from bovine brain phosphodiesterase, 3',5'-cyclic-nucleotide-specific from bovine brain CYCLIC 3'',5''-NUCLEOTIDE PHOSPHODIESTERASE (FROM BEEF HEART) phosphodiesterase, 3',5'-cyclic-nucleotide-specific PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from porcine brain Phosphodiesterase, 3μ,5μ-Cyclic Nucleotide, Activator-deficient from porcine brain PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from bovine brain PDE, 3μ,5μ-Cyclic-nucleotide 5μ-nucleotidohydrolase from bovine heart Phosphodiesterase 3μ,5μ-Cyclic Nucleotide Activator-deficient from bovine heart PHOSPHODIESTERASE PHOSPHODIESTERASE 3':5'-CYCLIC NUCLEOTIDE EC 3.1.4.17 PDE 3B Phosphodiesterase 3B Phosphodiesterase 3B, Recombinant Native Bovine Phosphodiesterase 3,5-Cyclic Nucleotide Activator-deficient Native Bovine Phosphodiesterase, 3,5-cyclic-nucleotide-specific Native Porcine Phosphodiesterase, 3,5-Cyclic Nucleotide, Activator-deficient Phosphodiesterase 3A from Human, Recombinant Phosphodiesterase, 3',5'-cyclic-nucleotide-specific from bovine brain 15-30 units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)), lyophilized powder (4-Nitrobenzyl)arsonic acid 9040-59-9 BioChemical Cell Signaling and Neuroscience Cell Biology Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides Enzymes