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ChemicalBook >> CAS DataBase List >>(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Structure
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE structure
CAS No.
22677-21-0
Chemical Name:
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
Synonyms
RHPD;In1122 Impurity 78;Oxiracetam Impurity P;(R)-4-hydoroxyoyrolidone;4-hydroxy-R-2-pyrrolidine;(R)-4-HYDROXY-2-PYRROLIDONE;(r)-β-hydroxy-γ-butyrolactam;（R)+4-hydroxy-2-prrolidinone;(R)-4-hydroxy-2-pyrrolidione;(4R)-4-hydroxy-2-pyrrolidone
CBNumber:
CB2438434
Molecular Formula:
C4H7NO2
Molecular Weight:
101.1
MDL Number:
MFCD00273364
MOL File:
22677-21-0.mol
MSDS File:
SDS
Last updated:2025-07-04 16:04:00
Product description Number Pack Size Price
(R)-(+)-4-Hydroxy-2-pyrrolidinone 97% 479160 1g $114
(R)-(+)-4-Hydroxy-2-pyrrolidinone 97% 479160 5g $417
(R)-(+)-4-Hydroxy-2-pyrrolidinone H953070 1g $1110
(R)-4-Hydroxypyrrolidin-2-one >98.0% CS-W013709 100g $1492
(R)-4-Hydroxypyrrolidin-2-one >98.0% CS-W013709 25g $521
More product size
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(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Properties

Melting point 156-160 °C
Boiling point 363.6±35.0 °C(Predicted)
Density 1.292±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
pka 13.62±0.20(Predicted)
form Powder
color White to pale yellow
optical activity [α]23/D +43°, c = 1 in ethanol
Water Solubility Slightly soluble in water.
BRN 1524193
InChI InChI=1S/C4H7NO2/c6-3-1-4(7)5-2-3/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1
InChIKey IOGISYQVOGVIEU-GSVOUGTGSA-N
SMILES N1C[C@H](O)CC1=O
CAS DataBase Reference 22677-21-0(CAS DataBase Reference)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-38-37-36
Safety Statements  26
WGK Germany  3
HS Code  29339900
NFPA 704
1
2 0

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 479160 (R)-(+)-4-Hydroxy-2-pyrrolidinone 97% 22677-21-0 1g $114 2025-07-31 Buy
Sigma-Aldrich 479160 (R)-(+)-4-Hydroxy-2-pyrrolidinone 97% 22677-21-0 5g $417 2023-06-20 Buy
TRC H953070 (R)-(+)-4-Hydroxy-2-pyrrolidinone 22677-21-0 1g $1110 2021-12-16 Buy
ChemScene CS-W013709 (R)-4-Hydroxypyrrolidin-2-one >98.0% 22677-21-0 100g $1492 2021-12-16 Buy
ChemScene CS-W013709 (R)-4-Hydroxypyrrolidin-2-one >98.0% 22677-21-0 25g $521 2021-12-16 Buy
Product number Packaging Price Buy
479160 1g $114 Buy
479160 5g $417 Buy
H953070 1g $1110 Buy
CS-W013709 100g $1492 Buy
CS-W013709 25g $521 Buy

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

The (R)-enantiomer intermediate in the preparation of Oxiracetam

Uses

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE synthesis

208103-39-3
22677-21-0
Synthesis of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE from Butanoic acid, 4-amino-3-hydroxy-, ethyl ester, (3R)-

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Butanoic acid, 4-amino-3-hydroxy-, ethyl ester, (3R)- 2-Pyrrolidinone, 1-[(1S)-1-phenylethyl]-4-(phenylmethoxy)-, (4R)-

Preparation Products

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Suppliers

Global( 186)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16515 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29850 58
Klong Industrial Co., Ltd 		0086-519-68231162 info@klongchem.com CHINA 131 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Klong Industrial Co., Ltd 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from (R)-(+)-4-HYDROXY-2-PYRROLIDINONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-(+)-4-Hydroxy-2-pyrrolidinone pictures 2025-10-13 (R)-(+)-4-Hydroxy-2-pyrrolidinone
22677-21-0
 US $3.00-9.00 / KG 0.1KG 99% g-kg-tons, free sample is available ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
(R)-(+)-4-HYDROXY-2-PYRROLIDINONE pictures 2019-07-06 (R)-(+)-4-HYDROXY-2-PYRROLIDINONE
22677-21-0
 US $1.00 / kg 1kg 95%-99% as request Career Henan Chemical Co

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Spectrum

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE(22677-21-0)1HNMR

22677-21-0((R)-(+)-4-HYDROXY-2-PYRROLIDINONE)Related Search:

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE (3R,4R)-1-Benzyl-3,4-dihydroxypyrrolidine-2,5-dione (S)-(+)-4-HYDROXY-2-PYRROLIDINONE,(S)-4-HYDROXY-2-PYRROLIDINONE,(S)-(-)-4-HYDROXY-2-PYRROLIDINONE 4-Hydroxy-2-pyrrolidinone (S)-(-)-3-hydroxy-2-pyrrolidinone
(S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE 3-HYDROXY-2-PYRROLIDINONE (S)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE ALPHA-PYRIDOIN (R)-(+)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE,(R)-1-BENZYL-4-HYDROXY-2-PYRROLIDINONE
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3-(3-METHOXY-PROPYL)-4-OXO-10-OXA-3-AZA-TRICYCLO[5.2.1.0(1,5)]DEC-8-ENE-6-CARBOXYLIC ACID (S)-4-HYDROXY-2-PYRROLIDINONE-1-N-ACETIC ACID R(+)-3-AMINO-1-HYDROXY-2-PYRROLIDINONE

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(R)-(+)-4-HYDROXY-2-PYRROLIDINONE (R)-4-HYDROXY-2-PYRROLIDINONE (R)-4-HYDROXY-2-PYRROLIDONE (R)-BETA-HYDROXY-GAMMA-BUTYROLACTAM RHPD 2-PYRROLIDINONE, 4-HYDROXY-, (R) 4-hydroxy-R-2-pyrrolidine (r)-(+)-β-hydroxy-γ-butyrolactam (r)-β-hydroxy-γ-butyrolactam 2-Pyrrolidinone, 4-hydroxy-, (4R)- (R)-4-hydoroxyoyrolidone （R)+4-hydroxy-2-prrolidinone (R)-4-Hydroxy-pyrrolidin-2-one (4R)-4-Hydroxypyrrolidine-2-one (R)-4β-Hydroxypyrrolidine-2-one [4R,(-)]-4-Hydroxypyrrolidin-2-one (R)-4-hydroxy-2-pyrrolidione (4R)-4-hydroxy-2-pyrrolidone (4R)-4-Hydroxy-2-pyrrolidinone In1122 Impurity 78 Oxiracetam Impurity P (R)-(+)-4-Hydroxy-2-pyrrolidinone, 97%, (R)-(+)-4-Hydroxy-2-pyrrolidinone (R)-4-hydroxypyrrolidin-2-one, 98%min 22677-21-0 Chiral Building Blocks Asymmetric Synthesis Heterocyclic Building Blocks Pyrrolidines Pyrrole&Pyrrolidine&Pyrroline Amines Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Drug Intermediates