DIAMINE OXIDASE
- CAS No.
- 9001-53-0
- Chemical Name:
- DIAMINE OXIDASE
- Synonyms
- EC 1.4.3.6;Histaminase;DIAMINE OXIDASE;Oxidase, diamine;EC NUMBER: 1.4.3.6;DIAMINE OXIDASE USP/EP/BP;Native Porcine Diamine Oxidase;amine oxidase, copper-containing;Diamine oxidase from Pea Sprouts;ENZYME COMMISSION NUMBER: 1.4.3.6
- CBNumber:
- CB2440996
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130946
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| solubility | 100 mM sodium phosphate buffer, pH 7.2: soluble10mg/mL |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
DIAMINE OXIDASE price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7876 | Diamine Oxidase from porcine kidney ≥0.05 unit/mg solid | 9001-53-0 | 1g | $289 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7876 | Diamine Oxidase from porcine kidney ≥0.05 unit/mg solid | 9001-53-0 | 5g | $877 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7876 | Diamine Oxidase from porcine kidney ≥0.05 unit/mg solid | 9001-53-0 | 250mg | $90.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7876 | Diamine Oxidase from porcine kidney ≥0.05 unit/mg solid | 9001-53-0 | 10g | $1540 | 2024-03-01 | Buy |
| Usbiological | 365935 | Diamine Oxidase | 9001-53-0 | 96Tests | $824 | 2021-12-16 | Buy |
DIAMINE OXIDASE Chemical Properties,Uses,Production
Uses
Diamine Oxidase from porcine kidney has been used in the construction of histamine biosensor.
Definition
An enzyme occurring in the animal digestive system; it converts histidine to histamine.
Biological Functions
Diamine oxidase attacks both diamines and histamine in much the same way that MAO attacks monoamines, forming aldehydes. This enzyme is inhibited by carbonyl-blocking reagents and produces hydrogen peroxide, supporting the role of pyridoxal phosphate and the flavin prosthetic groups in the catalytic action of the enzyme. Diamine oxidase is recovered in the supernatant after centrifugation and removal of particulate matter. It is present in kidneys, intestines, liver, lung, and nervous tissue. It limits the biological effects of histamine and the polymethylene amines putrescine and cadaverine. It also attacks monoamines, but at a higher substrate concentration.Plasma amine oxidases are in blood plasma of mammals and include spermine oxidase, which deaminates spermine and other polyamines.
General Description
Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.
Biochem/physiol Actions
Diamine Oxidase catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide. The enzyme is classified as a copper amine oxidase and it is a key enzyme in nitrogen metabolism. Diamine oxidase is inhibited by diethyldithiocarbamate, phenylhydrazine, semicarbazide, cyanide, isonicotinic acid hydrazide.
DIAMINE OXIDASE Preparation Products And Raw materials
Raw materials
Preparation Products
DIAMINE OXIDASE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2596 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 | sales@sunlidabio.com | China | 3750 | 55 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15878 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Raw material medicin reagent co.,Ltd | 025-57798860 | sales@njromanme.com | China | 4534 | 58 |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815688 13927872512 | 3007421951@qq.com | China | 10084 | 58 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
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